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Generalization methods offer a powerful solution to one of the key drawbacks of randomized controlled trials (RCTs): their limited representativeness. By enabling the transport of treatment effect estimates to target populations subject to…

Methodology · Statistics 2025-05-20 Ahmed Boughdiri , Clément Berenfeld , Julie Josse , Erwan Scornet

Psychiatric and social epidemiology often involves assessing the effects of environmental exposure on outcomes that are difficult to measure directly. To address this problem, it is common to measure outcomes using a comprehensive battery…

During the COVID-19 pandemic, the behavioral response to reported case numbers changed drastically over time. While a few dozen cases were enough to trigger government-induced and voluntary contact reduction in early 2020, less than a year…

Physics and Society · Physics 2023-09-27 Bastian Heinlein , Manlio De Domenico

The COVID-19 pandemic has had and continues to have major impacts on planned and ongoing clinical trials. Its effects on trial data create multiple potential statistical issues. The scale of impact is unprecedented, but when viewed…

Testing symptomatic individuals for a disease can deliver treatment resources, if tests' results turn positive, which speeds up their treatment and might also decrease individuals' contacts to other ones. An imperfect test, however, might…

Populations and Evolution · Quantitative Biology 2015-06-25 Daniel A. M. Villela

Social contact studies, investigating social contact patterns in a population sample, have been an important contribution for epidemic models to better fit real life epidemics. A contact matrix $M$, having the \emph{mean} number of contacts…

Populations and Evolution · Quantitative Biology 2024-08-15 Tom Britton , Frank Ball

The number of new infections per day is a key quantity for effective epidemic management. It can be estimated relatively directly by testing of random population samples. Without such direct epidemiological measurement, other approaches are…

Applications · Statistics 2021-06-18 Simon N. Wood

In this study, we explore the dynamic interplay between the timing of vaccination campaigns and the trajectory of disease spread in a population. Through comprehensive data analysis and modeling, we have uncovered a counter-intuitive…

Physics and Society · Physics 2024-12-06 Piergiorgio Castioni , Sergio Gòmez , Clara Granell , Alex Arenas

The cataclysmic contagion based calamity -- Covid-19 has shown us a clear need for a comprehensive community based strategy that overcomes the sheer complexity of controlling it and the caveats of current methods. In this regard, as seen in…

Physics and Society · Physics 2021-09-17 Surya Dheeshjith , Inavamsi Enaganti , Bud Mishra

Near-real time estimations of the effective reproduction number are among the most important tools to track the progression of a pandemic and to inform policy makers and the general public. However, these estimations rely on reported case…

Physics and Society · Physics 2022-07-25 Eszter Bokányi , Zsolt Vizi , Júlia Koltai , Gergely Röst , Márton Karsai

In the first half of 2020, several countries have responded to the challenges posed by the Covid-19 pandemic by restricting their export of medical supplies. Such measures are meant to increase the domestic availability of critical goods,…

Physics and Society · Physics 2021-12-28 Marco Grassia , Giuseppe Mangioni , Stefano Schiavo , Silvio Traverso

This research investigates the coupled dynamics of behavior and infectious disease using a mathematical model. We integrate a two-state q-voter opinion process with SIS-type infection dynamics, where transmission rates are influenced by the…

Physics and Society · Physics 2025-12-13 Thomas Goetz , Tyll Krueger , Karol Niedzielewski , Jan Schneider , Barbara Pabjan

Population inhomogeneity, in the variation of the individual social contact networks and the individual infectious-recovery rates, renders the dynamics of infectious disease spreading uncertain. As a consequence the overlaying economical…

Physics and Society · Physics 2021-09-01 Jan B. Broekaert , Davide La Torre

Information diffusion and disease spreading in communication-contact layered network are typically asymmetrically coupled with each other, in which how an individual being aware of disease responds to the disease can significantly affect…

Physics and Society · Physics 2016-06-20 Quan-Hui Liu , Wei Wang , Ming Tang , Hai-Feng Zhang

Test-negative designs (TNDs), a form of case-cohort study, are widely used to evaluate infectious disease interventions, notably for influenza and, more recently, COVID-19 vaccines. TNDs rely on recruiting individuals who are tested for the…

Methodology · Statistics 2025-04-29 Mengxin Yu , Nicholas P. Jewell

An epidemic carries human and fiscal costs. In the case of imported pandemics, the first-best solution is to restrict national borders to identify and isolate infected individuals. However, when that opportunity is not fully seized and…

Populations and Evolution · Quantitative Biology 2022-03-31 Mayteé Cruz-Aponte , José Caraballo-Cueto

Background: Incidence of adverse outcome events rises as patients with advanced illness approach end-of-life. Exposures that tend to occur near end-of-life, e.g., use of wheelchair, oxygen therapy and palliative care, may therefore be found…

The COVID-19 pandemic has forced public health experts to develop contingent policies to stem the spread of infection, including measures such as partial/complete lockdowns. The effectiveness of these policies has varied with geography,…

Social and Information Networks · Computer Science 2020-10-29 Parth Asawa , Manas Gaur , Kaushik Roy , Amit Sheth

Dehumanisation involves the perception and or treatment of a social group's members as less than human. This phenomenon is rarely addressed with computational linguistic techniques. We adapt a recently proposed approach for English, making…

Computation and Language · Computer Science 2024-04-11 Jaya Caporusso , Damar Hoogland , Mojca Brglez , Boshko Koloski , Matthew Purver , Senja Pollak

Multi-state models provide an extension of the usual survival/event-history analysis setting. In the medical domain, multi-state models give the possibility of further investigating intermediate events such as relapse and remission. In this…

Methodology · Statistics 2021-06-24 D. Manevski , H. Putter , M. Pohar Perme , E. F. Bonneville , J. Schetelig , L. C. de Wreede