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Patients do not access physicians at random but rather via naturally emerging networks of patient flows between them. As retirements, mass quarantines and absence due to sickness during pandemics, or other shocks thin out these networks,…

The U.S. Food and Drug Administration has cautioned that prenatal exposure to anesthetic drugs during the third trimester may have neurotoxic effects; however, there is limited clinical evidence available to substantiate this…

Applications · Statistics 2025-04-03 Amy J. Pitts , Ling Guo , Caleb Ing , Caleb H. Miles

Motivated by fundamental issues in non-equilibrium statistical mechanics (NESM), we study the venerable susceptible-infected (SIS) model of disease spreading in an idealized, simple setting. Using Monte Carlo and analytic techniques, we…

Statistical Mechanics · Physics 2015-06-22 Maxim S. Shkarayev , R. K. P. Zia

The Covid-19 pandemic drastically emphasized the fragility of national and international supply networks (SNs),leading to significant supply shortages of essential goods for people, such as food and medical equipment. Severe disruptions…

Understanding the dynamics of the spread of diseases within populations is critical for effective public health interventions. We extend the classical SIR model by incorporating additional complexities such as the introduction of a cure and…

Populations and Evolution · Quantitative Biology 2025-10-30 Daniel Perkins , Davis Hunter , Drake Brown , Trevor Garrity , Wyatt Pochman

While prior studies have examined the influence of information diffusion on epidemic dynamics, the role of affective polarisation--driven by digital media usage--remains less understood. This study introduces a mathematical framework to…

Social and Information Networks · Computer Science 2025-03-26 Satoshi Komuro

The age of big data has fueled expectations for accelerating learning. The availability of large data sets enables researchers to achieve more powerful statistical analyses and enhances the reliability of conclusions, which can be based on…

Methodology · Statistics 2023-08-22 Ori Becher , Mira Marcus-Kalish , David M. Steinberg

Massive changes in many aspects related to social groups of different socioeconomic backgrounds were caused by the COVID-19 pandemic and as a result, the overall state of mental health was severely affected globally. This study examined how…

This paper investigates the robustness of futility analyses in clinical trials when interim analysis population deviates from the target population. We demonstrate how population shifts can distort early stopping decisions and propose…

Methodology · Statistics 2025-07-31 Rui Jin , Cai Wu , Peter Mesenbrink

In this comment, I revisit the question raised in Karadja and Prawitz (2019) concerning a causal relationship between mass emigration and long-run political outcomes. I discuss a number of potential problems with their instrumental variable…

General Economics · Economics 2022-01-14 Per Pettersson-Lidbom

In this paper, we study the psychological effect in a SIS epidemic model. The basic reproduction number is obtained. However, the disease free equilibrium is always asymptotically stable, which doesn't depends on the basic reproduction…

Populations and Evolution · Quantitative Biology 2020-01-22 Shaoli Wang , Xiyan Bai

In this work, the SIR epidemiological model is reformulated so to highlight the important {\em effective reproduction number}, as well as to account for the {\em generation time}, inverse of the {\em incidence rate}, and the {\em infectious…

Populations and Evolution · Quantitative Biology 2021-07-27 Ignazio Lazzizzera

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

Chronic diseases frequently co-occur in patterns that are unlikely to arise by chance, a phenomenon known as multimorbidity. This growing challenge for patients and healthcare systems is amplified by demographic aging and the rising burden…

Physics and Society · Physics 2025-10-14 Johanna Einsiedler , Katharina Ledebur , Peter Klimek , Laust Hvas Mortensen

We present a new analysis of relationships between disease incidence and the prevalence of an experimentally defined state of `recent infection'. This leads to a clean separation between biological parameters (properties of disease…

Populations and Evolution · Quantitative Biology 2008-06-09 Thomas A. McWalter , Alex Welte

In this work we consider a model of epidemic spreading coupled with an opinion dynamics in a fully-connected population. Regarding the opinion dynamics, the individuals may be in two distinct states, namely in favor or against a vaccination…

Physics and Society · Physics 2016-10-28 Marcelo A. Pires , Nuno Crokidakis

Large-scale hazards affect societies not only through direct physical impacts but also through emotions that spread across populations. Fueled by social amplification and networked communication, collective emotions often diverge markedly…

Physics and Society · Physics 2026-04-01 Xiaolei Chu , Guanren Zhou , Marco Broccardo , Didier Sornette , Khalid M. Mosalam , Ziqi Wang

During the COVID-19 pandemic, many countries have developed and deployed contact tracing technologies to curb the spread of the disease by locating and isolating people who have been in contact with coronavirus carriers. Subsequently,…

Human-Computer Interaction · Computer Science 2025-01-09 Eran Toch , Oshrat Ayalon

The COVID-19 pandemic presents challenges to both public health and the economy. Our objective is to examine how household expenditure, a significant component of private demand, reacts to changes in mobility. This investigation is crucial…

Methodology · Statistics 2025-10-07 Taekwon Hong , Wenbin Lu , Shu Yang , Pulak Ghosh

Many datasets describing contacts in a population suffer from incompleteness due to population sampling and underreporting of contacts. Data-driven simulations of spreading processes using such incomplete data lead to an underestimation of…

Physics and Society · Physics 2017-09-07 Julie Fournet , Alain Barrat
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