Related papers: Spin-based magnetic detection of optically trapped…
Different approaches have improved the sensitivity of either electron or nuclear magnetic resonance to the single spin level. For optical detection it has essentially become routine to observe a single electron spin or nuclear spin.…
Optically detected magnetic resonance (ODMR) provides ultrasensitive means to detect and image a small number of electron and nuclear spins, down to the single spin level with nanoscale resolution. Despite the significant recent progress in…
Optical tweezers, the three-dimensional confinement of a nanoparticle by a strongly focused beam of light, have been widely employed in investigating biomaterial nanomechanics, nanoscopic fluid properties, and ultrasensitive detections in…
We investigated whether we can detect enhanced magnetic nanoparticle uptake under application of a large magnetic force by tagging the particles with a fluorescent dye. Human liver cells were cultured in a micro-channel slide and exposed to…
We perform balanced homodyne detection of the electromagnetic field in a single-mode tapered optical nanofiber surrounded by rubidium atoms in a magneto-optical trap. Resonant fluorescence of atoms into the nanofiber mode manifests itself…
Investigating the cellular internalization pathways of single molecules or single nano-objects is important to understanding cell-matter interactions and to applications in drug delivery and discovery. Imaging and tracking the motion of…
Red blood cells possess unique biomechanical ability to squeeze through capillaries smaller than their size to enable gas and ion exchange. A key signature of their active biomechanics is the out-of-equilibrium fluctuation of the plasma…
Novel techniques are currently being developed and established for the accurate chemical analysis and detection of single cancer cells, single embryos and single seeds by Fourier Transform Near Infrared (FT-NIR) Microspectroscopy, Fourier…
Magnetic spin resonance is a key non-invasive sensing and imaging technique across the life-, material- and fundamental sciences with further medical and commercial applications. Recent advances using paramagnetic color centers enable…
Magnetic resonance with ensembles of electron spins is nowadays performed in frequency ranges up to 240 GHz and in corresponding magnetic fields of up to 10 T. However, experiments with single electron and nuclear spins so far only reach…
Trapped, laser-cooled ions produce intense fluorescence. Detecting this fluorescence enables efficient measurement of quantum state of qubits based on trapped atoms. It is desirable to collect a large fraction of the photons to make the…
Molecular magnets are a promising class of materials with exciting properties and applications. However, a profound understanding and application of such materials depends on the accurate detection of their electronic and magnetic…
Total internal reflection fluorescence (TIRF) microscopy and its variants are key technologies for visualizing the dynamics of single molecules or organelles in live cells. Yet, truely quantitative TIRF remains problematic. One unknown…
Over the last decade, single-molecule optical microscopy has become the gold-standard approach to decipher complex molecular processes in cellular environments. [1-3] Single-molecule fluorescence microscopy has several advantages such as…
Since their invention in the 1980s [1], optical tweezers have found a wide range of applications, from biophotonics and mechanobiology to microscopy and optomechanics [2, 3, 4, 5]. Simulations of the motion of microscopic particles held by…
Magnetically modulated optical nanoprobes (MagMOONs) were used to detect and distinguish probe fluorescence from autofluorescent backgrounds in turbid media. MagMOONs are micro/nano-sized particles with magnetically controlled orientation…
We present an experimental method to perform dual-channel lock-in magnetometry of time-dependent magnetic fields using a single spin associated with a nitrogen-vacancy (NV) color center in diamond. We incorporate multi-pulse quantum sensing…
We demonstrate single-shot imaging and narrow-line cooling of individual alkaline earth atoms in optical tweezers; specifically, strontium-88 atoms trapped in $515.2~\text{nm}$ light. We achieve high-fidelity single-atom-resolved imaging by…
Surface enhanced Raman scattering (SERS) is optically sensitive and chemically specific to detect single molecule spectroscopic signatures. Facilitating this capability in optically-trapped nanoparticles at low laser power remains a…
Piezoelectric microresonators are indispensable in wireless communications, and underpin radio frequency filtering in mobile phones. These devices are usually analyzed in the quasi-(electro)static regime with the magnetic field effectively…