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Accurate prediction of functional outcomes after acute ischemic stroke can inform clinical decision-making and resource allocation. Prior work on modified Rankin Scale (mRS) prediction has relied primarily on structured variables (e.g.,…

The work in this paper evaluates zero-shot and few-shot large language models (LLMs) for safety-critical clinical action extraction using the CLIP discharge-note dataset, with particular emphasis on transitions of care and post-discharge…

Artificial Intelligence · Computer Science 2026-05-08 Shivali Dalmia , Ananya Mantravadi , Prasanna Desikan

Clinical notes recorded during a patient's perioperative journey holds immense informational value. Advances in large language models (LLMs) offer opportunities for bridging this gap. Using 84,875 pre-operative notes and its associated…

Computation and Language · Computer Science 2025-04-03 Charles Alba , Bing Xue , Joanna Abraham , Thomas Kannampallil , Chenyang Lu

With the advent of LLMs, various tasks across the natural language processing domain have been transformed. However, their application in predictive tasks remains less researched. This study compares large language models, including…

Artificial Intelligence · Computer Science 2025-12-24 Chehak Malhotra , Mehak Gopal , Akshaya Devadiga , Pradeep Singh , Ridam Pal , Ritwik Kashyap , Tavpritesh Sethi

Objective: Function is increasingly recognized as an important indicator of whole-person health. This study evaluates the ability of publicly available large language models (LLMs) to accurately identify the presence of functioning…

Computation and Language · Computer Science 2023-12-19 Tuan Dung Le , Thanh Duong , Thanh Thieu

Objective: To develop and evaluate machine learning (ML) models for predicting length of stay (LOS) in elective spine surgery, with a focus on the benefits of temporal modeling and model interpretability. Materials and Methods: We compared…

Machine Learning · Computer Science 2025-07-17 Ha Na Cho , Sairam Sutari , Alexander Lopez , Hansen Bow , Kai Zheng

Recent advancements in large language models (LLMs) hold significant promise in improving physics education research that uses machine learning. In this study, we compare the application of various models to perform large-scale analysis of…

Physics Education · Physics 2025-02-25 Rebeckah K. Fussell , Megan Flynn , Anil Damle , Michael F. J. Fox , N. G. Holmes

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

Intelligent drug recommendation based on Electronic Health Records (EHRs) is critical for improving the quality and efficiency of clinical decision-making. By leveraging large-scale patient data, drug recommendation systems can assist…

Computation and Language · Computer Science 2025-12-08 Juntao Li , Haobin Yuan , Ling Luo , Yan Jiang , Fan Wang , Ping Zhang , Huiyi Lv , Jian Wang , Yuanyuan Sun , Hongfei Lin

Generating discharge summaries is a crucial yet time-consuming task in clinical practice, essential for conveying pertinent patient information and facilitating continuity of care. Recent advancements in large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-01 Yiming Li , Fang Li , Kirk Roberts , Licong Cui , Cui Tao , Hua Xu

Foresight 2 (FS2) is a large language model fine-tuned on hospital data for modelling patient timelines (GitHub 'removed for anon'). It can understand patients' clinical notes and predict SNOMED codes for a wide range of biomedical use…

Computation and Language · Computer Science 2024-12-17 Zeljko Kraljevic , Joshua Au Yeung , Daniel Bean , James Teo , Richard J. Dobson

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

We evaluated the viability of using a Large Language Model (LLM) to extract patient-specific specific toxicity and progression outcomes from unstructured radiology reports. We retrospectively extracted 160 follow-up CT and PET/CT electronic…

Medical Physics · Physics 2026-03-02 Justin Pijanowski , Yakout Mezgueldi , Alan Lee , Drew Moghanaki , Ricky R. Savjani , James Lamb

Large language models (LLMs) excel at clinical information extraction but their computational demands limit practical deployment. Knowledge distillation--the process of transferring knowledge from larger to smaller models--offers a…

Computation and Language · Computer Science 2025-01-03 Karthik S. Vedula , Annika Gupta , Akshay Swaminathan , Ivan Lopez , Suhana Bedi , Nigam H. Shah

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

In the U.S. inpatient payment system, the Diagnosis-Related Group (DRG) is pivotal, but its assignment process is inefficient. The study introduces DRG-LLaMA, an advanced large language model (LLM) fine-tuned on clinical notes to enhance…

Artificial Intelligence · Computer Science 2023-10-02 Hanyin Wang , Chufan Gao , Christopher Dantona , Bryan Hull , Jimeng Sun

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

Computation and Language · Computer Science 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

The application of large language models (LLMs) to healthcare information extraction has emerged as a promising approach. This study evaluates the classification performance of five open-source LLMs: GEMMA-3-27B-IT, LLAMA3-70B, LLAMA4-109B,…

Computation and Language · Computer Science 2025-05-09 Yuting Guo , Abeed Sarker

Proprietary Large Language Models (LLMs) such as GPT-4 and Gemini have demonstrated promising capabilities in clinical text summarization tasks. However, due to patient data privacy concerns and computational costs, many healthcare…

Large language models (LLMs) have shown considerable promise in clinical natural language processing, yet few domain-specific datasets exist to rigorously evaluate their performance on radiology tasks. In this work, we introduce an…

Computation and Language · Computer Science 2025-11-18 Namu Park , Giridhar Kaushik Ramachandran , Kevin Lybarger , Fei Xia , Ozlem Uzuner , Meliha Yetisgen , Martin Gunn
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