English
Related papers

Related papers: Optimal Experimental Design using Eigenvalue-Based…

200 papers

Questions of `how best to acquire data' are essential to modeling and prediction in the natural and social sciences, engineering applications, and beyond. Optimal experimental design (OED) formalizes these questions and creates…

Methodology · Statistics 2026-05-01 Xun Huan , Jayanth Jagalur , Youssef Marzouk

This paper introduces ROmodel, an open source Python package extending the modeling capabilities of the algebraic modeling language Pyomo to robust optimization problems. ROmodel helps practitioners transition from deterministic to robust…

Optimization and Control · Mathematics 2021-05-19 Johannes Wiebe , Ruth Misener

Mechanistic mathematical models of biological systems usually contain a number of unknown parameters whose values need to be estimated from available experimental data in order for the models to be validated and used to make quantitative…

Quantitative Methods · Quantitative Biology 2025-06-16 Yue Liu , Philip K. Maini , Ruth E. Baker

Engineering problems that are modeled using sophisticated mathematical methods or are characterized by expensive-to-conduct tests or experiments, are encumbered with limited budget or finite computational resources. Moreover, practical…

Machine Learning · Computer Science 2021-12-24 Yonatan Ashenafi , Piyush Pandita , Sayan Ghosh

Large Language Model (LLM)-based scientific agents have accelerated scientific discovery, yet they often suffer from significant inefficiencies due to adherence to fixed initial priors. Existing approaches predominantly operate within a…

Machine Learning · Computer Science 2026-02-09 Yingming Pu , Tao Lin , Hongyu Chen

We present a review of methods for optimal experimental design (OED) for Bayesian inverse problems governed by partial differential equations with infinite-dimensional parameters. The focus is on problems where one seeks to optimize the…

Optimization and Control · Mathematics 2021-02-01 Alen Alexanderian

The calibration of simulators for complex social systems aims to identify the optimal parameter that drives the output of the simulator best matching the target data observed from the system. As many social systems may change internally…

Neural and Evolutionary Computing · Computer Science 2026-01-28 Peng Yang , Zhenhua Yang , Boquan Jiang , Chenkai Wang , Ke Tang , Xin Yao

Biomanufacturing innovation relies on an efficient Design of Experiments (DoEs) to optimize processes and product quality. Traditional DoE methods, ignoring the underlying bioprocessing mechanisms, often suffer from a lack of…

Quantitative Methods · Quantitative Biology 2024-07-01 Fuqiang Cheng , Wei Xie , Hua Zheng

When the experimental objective is expressed by a set of estimable functions, and any eigenvalue-based optimality criterion is selected, we prove the equivalence of the recently introduced weighted optimality and the 'standard' optimality…

Statistics Theory · Mathematics 2016-10-21 Samuel Rosa

In line with the AI-native 6G vision, explainability and robustness are crucial for building trust and ensuring reliable performance in millimeter-wave (mmWave) systems. Efficient beam alignment is essential for initial access, but deep…

Machine Learning · Computer Science 2025-07-22 Nasir Khan , Asmaa Abdallah , Abdulkadir Celik , Ahmed M. Eltawil , Sinem Coleri

The objective of this Philosophiae Doctor (Ph.D) thesis is to propose an efficient approach for optimizing a multidisciplinary black-box model when the optimization problem is constrained and involves a large number of mixed integer design…

Optimization and Control · Mathematics 2025-07-24 Paul Saves

We develop a framework for goal-oriented optimal design of experiments (GOODE) for large-scale Bayesian linear inverse problems governed by PDEs. This framework differs from classical Bayesian optimal design of experiments (ODE) in the…

Computational Engineering, Finance, and Science · Computer Science 2018-08-15 Ahmed Attia , Alen Alexanderian , Arvind K. Saibaba

Despite the computational efficiency of MoE models, the excessive memory footprint and I/O overhead inherent in multi-expert architectures pose formidable challenges for real-time inference on resource-constrained edge platforms. While…

Machine Learning · Computer Science 2026-03-20 Yuegui Huang , Zhiyuan Fang , Weiqi Luo , Ruoyu Wu , Wuhui Chen , Zibin Zheng

Optimal experimental design provides a way of determining a-priori the best locations at which to place accelerometers in vibrations analysis experiments. However, in practice, sensors often fail during experimentation due high mechanical…

Computational Engineering, Finance, and Science · Computer Science 2026-04-17 Rebekah White , Chandler Smith , Drew Kouri , Jace Ritchie , Wilkins Aquino , Timothy Walsh

The development of Digital Twins (DTs) represents a transformative advance for simulating and optimizing complex systems in a controlled digital space. Despite their potential, the challenge of constructing DTs that accurately replicate and…

Systems and Control · Electrical Eng. & Systems 2024-06-21 Longfei Ma , Nan Cheng , Xiucheng Wang , Jiong Chen , Yinjun Gao , Dongxiao Zhang , Jun-Jie Zhang

Digital Twins (DTs) are becoming increasingly vital for future industrial applications, enhancing monitoring, control, and optimization of physical assets. This enhancement is made possible by integrating various Digital Models (DMs) within…

Real-life engineering optimization problems need Multiobjective Optimization (MOO) tools. These problems are highly nonlinear. As the process of Multiple Criteria Decision-Making (MCDM) is much expanded most MOO problems in different…

Software Engineering · Computer Science 2010-04-20 A. Mosavi

Analogy Based Effort Estimation (ABE) is one of the prominent methods for software effort estimation. The fundamental concept of ABE is closer to the mentality of expert estimation but with an automated procedure in which the final estimate…

Software Engineering · Computer Science 2017-01-09 Mohammad Azzeh , Ali Bou Nassif , Shadi Banitaan , Fadi Almasalha

Computational models are powerful tools for understanding human cognition and behavior. They let us express our theories clearly and precisely, and offer predictions that can be subtle and often counter-intuitive. However, this same…

Molecular optimization is a fundamental goal in the chemical sciences and is of central interest to drug and material design. In recent years, significant progress has been made in solving challenging problems across various aspects of…

Computational Engineering, Finance, and Science · Computer Science 2022-10-11 Wenhao Gao , Tianfan Fu , Jimeng Sun , Connor W. Coley