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Though modern microscopes have an autofocusing system to ensure optimal focus, out-of-focus images can still occur when cells within the medium are not all in the same focal plane, affecting the image quality for medical diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-31 Ioana Mazilu , Shunxin Wang , Sven Dummer , Raymond Veldhuis , Christoph Brune , Nicola Strisciuglio

High-numerical-aperture (NA) oblique plane microscopy enables noninvasive fluorescence imaging of subcellular dynamics without requiring radical sample modification. However, performance degrades at depth in multicellular specimens as…

We present the design, fabrication, and characterization of mode-selective photonic lanterns using double-clad fibers. Here, we exploited several custom-pulled double-clad fibers to achieve the symmetry break required to excite higher-order…

The contemporary superconductive electronics is widely using planar circuits with micrometer-scale elements for a variety of applications. With the rise of complexity of a circuit and increased number of its components, a simple impedance…

Applied Physics · Physics 2019-07-24 A. Karpov , A. P. Zhuravel , A. S. Averkin , V. I. Chichkov , A. V. Ustinov

For decades since the development of phase-contrast optical microscopy, an analogous approach has been sought for maximizing the image contrast of weakly-scattering objects in transmission electron microscopy (TEM). The recent development…

We demonstrate a method to double the collection efficiency in Laser Tweezers Raman Spectroscopy (LTRS) by collecting both the forward and back-scattered light in a single-shot multitrack measurement. Our method can collect signals at…

Optics · Physics 2021-06-09 Tobias Dahlberg , Magnus Andersson

Fourier Ptychographic Microscopy (FPM) is a computational imaging method that is able to super-resolve features beyond the diffraction-limit set by the objective lens of a traditional microscope. This is accomplished by using synthetic…

Signal Processing · Electrical Eng. & Systems 2019-04-09 Michael Kellman , Emrah Bostan , Michael Chen , Laura Waller

The combination of different imaging modalities into single imaging platforms has a strong potential in biomedical sciences since it permits the analysis of complementary properties of the target sample. Here, we report on an extremely…

Optics · Physics 2025-01-17 David Alonso , Javier Garcia , Vicente Mico

We report a time-resolved single photon counting (TCSPC) imaging system based on a line-scanning architecture. The system benefits from the high fill-factor, active area, and large dimension of an advanced CMOS single photon avalanche diode…

Aberrations and multiple scattering in biological tissues critically distort light beams into highly complex speckle patterns. In this regard, digital optical phase conjugation (DOPC) is a promising technique enabling in-depth focusing.…

In this work we deal with the problem of simultaneous multifrequency detection of extragalactic point sources in maps of the Cosmic Microwave Background. We apply a linear filtering technique that uses spatial information and the…

Cosmology and Nongalactic Astrophysics · Physics 2015-05-13 L. F. Lanz , D. Herranz , J. L. Sanz , J. González-Nuevo , M. López-Caniego

Spectroscopic photoemission microscopy is a well-established method to investigate the electronic structure of surfaces. In modern photoemission microscopes the electron optics allows imaging of the image plane, momentum plane, or…

A recently introduced two-channel confocal microscope with correlated detection promises up to 50% improvement in transverse spatial resolution [Simon, Sergienko, Optics Express {\bf 18}, 9765 (2010)] via the use of photon correlations.…

Quantum Physics · Physics 2015-05-18 D. S. Simon , A. V. Sergienko

Non-contact scanning probe microscopy (SPM) has developed into a powerful technique to image many different properties of samples. The conventional method involves monitoring the amplitude, phase or frequency of a cantilever oscillating at…

Mesoscale and Nanoscale Physics · Physics 2015-06-16 Manan Mehta , Venkat Chandrasekhar

Scanning fluorescence correlation spectroscopy (SFCS) with a scan path perpendicular to the membrane plane was introduced to measure diffusion and interactions of fluorescent components in free standing biomembranes. Using a confocal laser…

Biomolecules · Quantitative Biology 2018-06-04 Paul Müller , Petra Schwille , Thomas Weidemann

We designed and built a new astronomical photo-polarimeter that can measure linear polarization simultaneously in three spectral bands. It has a Calcite beamdisplacement prism as the analyzer. The ordinary and extra-ordinary emerging beams…

Instrumentation and Methods for Astrophysics · Physics 2015-05-19 G. Srinivasulu , A. V. Raveendran , S. Muneer , M. V. Mekkaden , N. Jayavel , M. R. Somashekar , K. Sagayanathan , S. Ramamoorthy , M. J. Rosario , K. Jayakumar

Optical computing is emerging as a promising platform for energy-efficient, high-throughput hardware in deep learning. A key challenge lies in the realization of optical matrix-vector multiplication, which often requires $O(N^2)$ phase…

Optics · Physics 2025-09-16 Yoshitaka Taguchi

Light with complex structures in polarization, phase and amplitude, has attracted a lot of attention in a broad range of applications and fundamental studies in classical and quantum optics. Along with the increased interest in structured…

Optics · Physics 2026-04-22 Oussama Korichi , Markus Hiekkamaki , Robert Fickler

Using photonic devices, we developed a new approach to traditional spectroscopy where the spectral cross-correlation with a template spectrum can be done entirely on-device. By creating photonic devices with a carefully designed, modulated…

In the paper we present a low cost optical device which splits the light in the focal plane into two separate optical paths and collimates it back into a single image plane, and where a selective information processing ca be carried out.…

Instrumentation and Methods for Astrophysics · Physics 2016-08-24 Adam Popowicz , Tomasz Blachowicz