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Deterministic computer simulations are often used as a replacement for complex physical experiments. Although less expensive than physical experimentation, computer codes can still be time-consuming to run. An effective strategy for…

Methodology · Statistics 2010-03-04 Mark Franey , Pritam Ranjan , Hugh Chipman

Excitatory point processes (i.e., event flows) occurring over dynamic graphs (i.e., evolving topologies) provide a fine-grained model to capture how discrete events may spread over time and space. How to effectively steer the event flows by…

Machine Learning · Computer Science 2024-04-16 Zitao Song , Wendi Ren , Shuang Li

Despite the extensive use of the agent technology in the Supply Chain Management field, its integration with Advanced Planning and Scheduling (APS) tools still represents a promising field with several open research questions. Specifically,…

Multiagent Systems · Computer Science 2011-07-19 Luis Antonio de Santa-Eulalia , Sophie D'Amours , Jean-Marc Frayret

Agent-based models (ABMs) simulate complex systems by capturing the bottom-up interactions of individual agents comprising the system. Many complex systems of interest, such as epidemics or financial markets, involve thousands or even…

Interprofessional education has long relied on case studies and the use of standardized patients to support teamwork, communication, and related collaborative competencies among healthcare professionals. However, traditional approaches are…

Emerging Technologies · Computer Science 2026-02-13 Ruijie Wang , Jie Lu , Bo Pei , Evonne Jones , Jamey Brinson , Timothy Brown

The COVID-19 pandemic highlighted the limitations of existing epidemic simulation tools. These tools provide information that guides non-pharmaceutical interventions (NPIs), yet many struggle to capture complex dynamics while remaining…

Multiagent Systems · Computer Science 2026-02-13 Zhijian Gao , Shuxin Li , Bo An

Computational disease modeling plays a crucial role in understanding and controlling the transmission of infectious diseases. While agent-based models (ABMs) provide detailed insights into individual dynamics, accurately replicating human…

In a number of cases, the Quantile Gaussian Process (QGP) has proven effective in emulating stochastic, univariate computer model output (Plumlee and Tuo, 2014). In this paper, we develop an approach that uses this emulation approach within…

National responses to the Covid-19 pandemic varied markedly across countries, from business-as-usual to complete shutdowns. Policies aimed at disrupting the viral transmission cycle and preventing the healthcare system from being…

Populations and Evolution · Quantitative Biology 2021-10-27 Arash Saeidpour , Pejman Rohani

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

Machine Learning · Computer Science 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

Acute infection, if not rapidly and accurately detected, can lead to sepsis, organ failure and even death. Current detection of acute infection as well as assessment of a patient's severity of illness are imperfect. Characterization of a…

Machine Learning · Computer Science 2020-10-14 Michael B. Mayhew , Elizabeth Tran , Kirindi Choi , Uros Midic , Roland Luethy , Nandita Damaraju , Ljubomir Buturovic

This paper describes an agent-based model of epidemics dynamics. This model is willingly simplified, as its goal is not to predict the evolution of the epidemics, but to explain the underlying mechanisms in an interactive way. This model…

Multiagent Systems · Computer Science 2024-04-16 Carole Adam , Helene Arduin

In this paper, we study the dynamics of epidemic processes taking place in adaptive networks of arbitrary topology. We focus our study on the adaptive susceptible-infected-susceptible (ASIS) model, where healthy individuals are allowed to…

Social and Information Networks · Computer Science 2016-06-29 Masaki Ogura , Victor M. Preciado

Prompt injection attacks pose a significant challenge to the safe deployment of Large Language Models (LLMs) in real-world applications. While prompt-based detection offers a lightweight and interpretable defense strategy, its effectiveness…

Cryptography and Security · Computer Science 2025-10-10 Ting-Chun Liu , Ching-Yu Hsu , Kuan-Yi Lee , Chi-An Fu , Hung-yi Lee

With recent and rapid advancements in artificial intelligence (AI), understanding the foundation of purposeful behaviour in autonomous agents is crucial for developing safe and efficient systems. While artificial neural networks have…

Artificial Intelligence · Computer Science 2025-08-12 Aswin Paul , Moein Khajehnejad , Forough Habibollahi , Brett J. Kagan , Adeel Razi

Anti-viral therapies are typically designed to target only the current strains of a virus, a myopic response. However, therapy-induced selective pressures drive the emergence of new viral strains, against which the original myopic therapies…

Machine learning systems deployed in medical devices require governance frameworks that ensure safety while enabling continuous improvement. Regulatory bodies including the FDA and European Union have introduced mechanisms such as the…

Machine Learning · Computer Science 2026-03-25 Fardin Afdideh , Mehdi Astaraki , Fernando Seoane , Farhad Abtahi

Agent-Based Models are very useful for simulation of physical or social processes, such as the spreading of a pandemic in a city. Such models proceed by specifying the behavior of individuals (agents) and their interactions, and…

Multiagent Systems · Computer Science 2023-01-31 Varun Madhavan , Adway Mitra , Partha Pratim Chakrabarti

Inpatient pathways demand complex clinical decision-making based on comprehensive patient information, posing critical challenges for clinicians. Despite advancements in large language models (LLMs) in medical applications, limited research…

Artificial Intelligence · Computer Science 2025-03-18 Zhen Chen , Zhihao Peng , Xusheng Liang , Cheng Wang , Peigan Liang , Linsheng Zeng , Minjie Ju , Yixuan Yuan

The widespread, and in many countries unprecedented, use of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic has highlighted the need for mathematical models which can estimate the impact of these measures while…