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This paper presents a scenario-based model predictive control (MPC) scheme designed to control an evolving pandemic via non-pharmaceutical intervention (NPIs). The proposed approach combines predictions of possible pandemic evolution to…

Systems and Control · Electrical Eng. & Systems 2025-06-24 Domagoj Herceg , Marco DellOro , Riccardo Bertollo , Fuminari Miura , Paul de Klaver , Valentina Breschi , Dinesh Krishnamoorthy , Mauro Salazar

This study investigates the spatial integration of agent-based models (ABMs) and compartmental models for infectious disease modeling, presenting a novel hybrid approach and examining its implications. ABMs offer detailed insights by…

Populations and Evolution · Quantitative Biology 2025-02-06 Inan Bostanci , Tim Conrad

The integration of external data services (e.g., Model Context Protocol, MCP) has made large language model-based agents increasingly powerful for complex task execution. However, this advancement introduces critical security…

Cryptography and Security · Computer Science 2026-02-25 Che Wang , Jiaming Zhang , Ziqi Zhang , Zijie Wang , Yinghui Wang , Jianbo Gao , Tao Wei , Zhong Chen , Wei Yang Bryan Lim

Infectious diseases and human behavior are intertwined. On one side, our movements and interactions are the engines of transmission. On the other, the unfolding of viruses might induce changes to our daily activities. While intuitive, our…

Physics and Society · Physics 2021-06-02 Nicola Perra

In many applications involving multi-agent system (MAS), it is imperative to test an experimental (Exp) autonomous agent in a high-fidelity simulator prior to its deployment to production, to avoid unexpected losses in the real-world. Such…

Machine Learning · Computer Science 2023-11-21 Song Wei , Andrea Coletta , Svitlana Vyetrenko , Tucker Balch

Nonpharmaceutical interventions (NPI) such as banning public events or instituting lockdowns have been widely applied around the world to control the current COVID-19 pandemic. Typically, this type of intervention is imposed when an…

Optimization and Control · Mathematics 2020-11-03 Carla Castillo-Laborde , Taco de Wolff , Pedro Gajardo , Rodrigo Lecaros , Gerard Olivar , Hector Ramirez C

Numerical simulation of continuous-time Markovian processes is an essential and widely applied tool in the investigation of epidemic spreading on complex networks. Due to the high heterogeneity of the connectivity structure through which…

Physics and Society · Physics 2017-07-26 Wesley Cota , Silvio C. Ferreira

Recent advancements in large language models (LLMs) have enabled a wide range of natural language processing (NLP) tasks to be performed through simple prompt-based interactions. Consequently, several approaches have been proposed to…

Computation and Language · Computer Science 2025-08-14 Artem Chernodub , Aman Saini , Yejin Huh , Vivek Kulkarni , Vipul Raheja

This study offers a new paradigm of individual-level modeling to address the grand challenge of incorporating human behavior in epidemic models. Using generative artificial intelligence in an agent-based epidemic model, each agent is…

Artificial Intelligence · Computer Science 2023-07-12 Ross Williams , Niyousha Hosseinichimeh , Aritra Majumdar , Navid Ghaffarzadegan

Crisis response requires information intensive efforts utilized for reducing uncertainty, calculating and comparing costs and benefits, and managing resources in a fashion beyond those regularly available to handle routine problems. This…

Multiagent Systems · Computer Science 2010-04-23 Khaled M. Khalil , M. Abdel-Aziz , Taymour T. Nazmy , Abdel-Badeeh M. Salem

Non-pharmaceutical interventions (NPIs) such as quarantine, self-isolation, social distancing, and virus-contact tracing can greatly reduce the spread of the virus during a pandemic. In the wave of the COVID-19 pandemic, many countries have…

Physics and Society · Physics 2020-12-16 Jingjing He , Xuefei Guan , Xiaochang Duan , Tian Shen , Jing Lin

HIV/AIDS spread depends upon complex patterns of interaction among various sub-sets emerging at population level. This added complexity makes it difficult to study and model AIDS and its dynamics. AIDS is therefore a natural candidate to be…

Multiagent Systems · Computer Science 2017-08-11 Amnah Siddiqa , Muaz A. Niazi

The integration of AI into modern critical infrastructure systems, such as healthcare, has introduced new vulnerabilities that can significantly impact workflow, efficiency, and safety. Additionally, the increased connectivity has made…

Cryptography and Security · Computer Science 2024-11-04 Haozhe Lei , Yunfei Ge , Quanyan Zhu

Behavioral health interventions, delivered through digital platforms, have the potential to significantly improve health outcomes, through education, motivation, reminders, and outreach. We study the problem of optimizing personalized…

Machine Learning · Computer Science 2024-07-19 Jackie Baek , Justin J. Boutilier , Vivek F. Farias , Jonas Oddur Jonasson , Erez Yoeli

Two simple agent based models are often employed in epidemic studies: the susceptible-infected (SI) and the susceptible-infected-susceptible (SIS). Both models describe the time evolution of infectious diseases in networks in which vertices…

Non-pharmaceutical interventions (NPIs) are effective measures to contain a pandemic. Yet, such control measures commonly have a negative effect on the economy. Here, we propose a macro-level approach to support resolving this…

Neural and Evolutionary Computing · Computer Science 2021-02-25 Rohit Salgotra , Thomas Seidelmann , Dominik Fischer , Sanaz Mostaghim , Amiram Moshaiov

Non-pharmaceutical interventions (NPIs), including mask-wearing, physical distancing, and hygiene measures, provide the primary means of reducing transmission in the early stages of an epidemic. Individuals adopt one of two…

Populations and Evolution · Quantitative Biology 2026-05-22 Yuan Liu , Michael Sieber , Bin Wu , Arne Traulsen

Predictive atomistic simulations have propelled materials discovery, yet routine setup and debugging still demand computer specialists. This know-how gap limits Integrated Computational Materials Engineering (ICME), where state-of-the-art…

Simulation-based optimization using agent-based models is typically carried out under the assumption that the gradient describing the sensitivity of the simulation output to the input cannot be evaluated directly. To still apply…

Machine Learning · Computer Science 2021-03-24 Philipp Andelfinger

Epidemiologists model the dynamics of epidemics in order to propose control strategies based on pharmaceutical and non-pharmaceutical interventions (contact limitation, lock down, vaccination, etc). Hand-designing such strategies is not…