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Training models on spatio-temporal (ST) data poses an open problem due to the complicated and diverse nature of the data itself, and it is challenging to ensure the model's performance directly trained on the original ST data. While…

Machine Learning · Computer Science 2024-09-17 Du Yin , Jinliang Deng , Shuang Ao , Zechen Li , Hao Xue , Arian Prabowo , Renhe Jiang , Xuan Song , Flora Salim

Large vision foundation models have been widely adopted for retinal disease classification without systematic evidence justifying their parameter requirements. In the present work we address two critical questions: First, are large…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 David Isztl , Tahm Spitznagel , Gabor Mark Somfai , Rui Santos

Spatial reasoning and visual grounding are core capabilities for vision-language models (VLMs), yet most medical VLMs produce predictions without transparent reasoning or spatial evidence. Existing benchmarks also evaluate VLMs on isolated…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Lama Moukheiber , Caleb M. Yeung , Haotian Xue , Alec Helbling , Zelin Zhao , Yongxin Chen

Solving tough clinical questions that require both image and text understanding is still a major challenge in healthcare AI. In this work, we propose Q-FSRU, a new model that combines Frequency Spectrum Representation and Fusion (FSRU) with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Rakesh Thakur , Yusra Tariq , Rakesh Chandra Joshi

In this work we introduce a self-supervised pretraining framework for transformers on functional Magnetic Resonance Imaging (fMRI) data. First, we pretrain our architecture on two self-supervised tasks simultaneously to teach the model a…

Machine Learning · Computer Science 2023-05-17 Sean Paulsen , Michael Casey

Frontier artificial intelligence (AI) models, such as OpenAI's GPT-5 and Meta's DINOv3, have advanced rapidly through training on internet-scale public data, yet such systems lack access to private clinical data. Neuroimaging, in…

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

We present TFF, which is a Transformer framework for the analysis of functional Magnetic Resonance Imaging (fMRI) data. TFF employs a two-phase training approach. First, self-supervised training is applied to a collection of fMRI scans,…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Itzik Malkiel , Gony Rosenman , Lior Wolf , Talma Hendler

As the potential of foundation models in visual tasks has garnered significant attention, pretraining these models before downstream tasks has become a crucial step. The three key factors in pretraining foundation models are the pretraining…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Keumgang Cha , Junghoon Seo , Taekyung Lee

Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…

Writing radiology reports from medical images requires a high level of domain expertise. It is time-consuming even for trained radiologists and can be error-prone for inexperienced radiologists. It would be appealing to automate this task…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yuzhe Lu , Sungmin Hong , Yash Shah , Panpan Xu

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

Non-rigid registration is a necessary but challenging task in medical imaging studies. Recently, unsupervised registration models have shown good performance, but they often require a large-scale training dataset and long training times.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-22 Heejung Park , Gyeong Min Lee , Soopil Kim , Ga Hyung Ryu , Areum Jeong , Sang Hyun Park , Min Sagong

Foundation models have become a promising paradigm for advancing medical image analysis, particularly for segmentation tasks where downstream applications often emerge sequentially. Existing fine-tuning strategies, however, remain limited:…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Yiwen Ye , Yicheng Wu , Xiangde Luo , He Zhang , Ziyang Chen , Ting Dang , Yanning Zhang , Yong Xia

Recent advancements in large language models have significantly accelerated their adoption in healthcare applications, including AI-powered medical consultations, diagnostic report assistance, and medical search tools. However, medical…

State-of-the-art results in large language models (LLMs) often rely on scale, which becomes computationally expensive. This has sparked a research agenda to reduce these models' parameter counts and computational costs without significantly…

Computation and Language · Computer Science 2024-11-07 Xiuying Wei , Skander Moalla , Razvan Pascanu , Caglar Gulcehre

Foundation models open up new possibilities for the use of AI in healthcare. However, even when pre-trained on health data, they still need to be fine-tuned for specific downstream tasks. Furthermore, although foundation models reduce the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Adam Tupper , Christian Gagné

The widespread use of Magnetic Resonance Imaging (MRI) in combination with deep learning shows promise for many high-impact automated diagnostic and prognostic tools. However, training new models requires large amounts of labeled data, a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Haoyu Dong , Yuwen Chen , Hanxue Gu , Nicholas Konz , Yaqian Chen , Qihang Li , Maciej A. Mazurowski

Diffusion models have been increasingly used as strong generative priors for solving inverse problems such as super-resolution in medical imaging. However, these approaches typically utilize a diffusion prior trained at a single scale,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Darshan Thaker , Mahmoud Mostapha , Radu Miron , Shihan Qiu , Mariappan Nadar

Accurate morphometric assessment of cartilage-such as thickness/volume-via MRI is essential for monitoring knee osteoarthritis. Segmenting cartilage remains challenging and dependent on extensive expert-annotated datasets, which are heavily…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Danielle L. Ferreira , Bruno A. A. Nunes , Xuzhe Zhang , Laura Carretero Gomez , Maggie Fung , Ravi Soni
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