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Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

The modern deep learning field is a scale-centric one. Larger models have been shown to consistently perform better than smaller models of similar architecture. In many sub-domains of biomedical research, however, the model scaling is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Nicholas Kuang , Vanessa Scalon , Ji Yu

Medical vision-language models can automate the generation of radiology reports but struggle with accurate visual grounding and factual consistency. Existing models often misalign textual findings with visual evidence, leading to unreliable…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Pablo Messina , Andrés Villa , Juan León Alcázar , Karen Sánchez , Carlos Hinojosa , Denis Parra , Álvaro Soto , Bernard Ghanem

Foundation models, trained on vast amounts of data using self-supervised techniques, have emerged as a promising frontier for advancing artificial intelligence (AI) applications in medicine. This study evaluates three different…

We study the problem of training self-supervised foundation models for functional MRI. Our main contributions are: (1) we introduce a new model family (CortexMAE) trained using the masked autoencoder framework on 2.1K hours of open fMRI…

Foundation models (FMs) are large-scale deep learning models trained on massive datasets, often using self-supervised learning techniques. These models serve as a versatile base for a wide range of downstream tasks, including those in…

Machine Learning · Computer Science 2025-01-17 Wasif Khan , Seowung Leem , Kyle B. See , Joshua K. Wong , Shaoting Zhang , Ruogu Fang

Foundation models have revolutionized computer vision by achieving vastly superior performance across diverse tasks through large-scale pretraining on extensive datasets. However, their application in surgical computer vision has been…

3D structural Magnetic Resonance Imaging (MRI) brain scans are commonly acquired in clinical settings to monitor a wide range of neurological conditions, including neurodegenerative disorders and stroke. While deep learning models have…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Dequan Wang , Xiaosong Wang , Lilong Wang , Mengzhang Li , Qian Da , Xiaoqiang Liu , Xiangyu Gao , Jun Shen , Junjun He , Tian Shen , Qi Duan , Jie Zhao , Kang Li , Yu Qiao , Shaoting Zhang

While foundation models in radiology are expected to be applied to various clinical tasks, computational cost constraints remain a major challenge when training on 3D-CT volumetric data. In this study, we propose TotalFM, a radiological…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Kohei Yamamoto , Tomohiro Kikuchi

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Clinical deployment of automated brain MRI analysis faces a fundamental challenge: clinical data is heterogeneous and noisy, and high-quality labels are prohibitively costly to obtain. Self-supervised learning (SSL) can address this by…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Asbjørn Munk , Stefano Cerri , Vardan Nersesjan , Christian Hedeager Krag , Jakob Ambsdorf , Pablo Rocamora García , Julia Machnio , Peirong Liu , Suhyun Ahn , Nasrin Akbari , Yasmina Al Khalil , Kimberly Amador , Sina Amirrajab , Tal Arbel , Meritxell Bach Cuadra , Ujjwal Baid , Bhakti Baheti , Jaume Banus , Kamil Barbierik , Christoph Brune , Yansong Bu , Baptiste Callard , Yuhan Chen , Cornelius Crijnen , Corentin Dancette , Peter Drotar , Prasad Dutande , Nils D. Forkert , Saurabh Garg , Jakub Gazda , Matej Gazda , Benoît Gérin , Partha Ghosh , Weikang Gong , Pedro M. Gordaliza , Sam Hashemi , Tobias Heimann , Fucang Jia , Jiexin Jiang , Emily Kaczmarek , Chris Kang , Seung Kwan Kang , Mohammad Khazaei , Julien Khlaut , Petros Koutsouvelis , Jae Sung Lee , Yuchong Li , Mengye Lyu , Mingchen Ma , Anant Madabhushi , Klaus H. Maier-Hein , Pierre Manceron , Andrés Martínez Mora , Moona Mazher , Felix Meister , Nataliia Molchanova , Steven A. Niederer , Leonard Nürnberg , Jinah Park , Abdul Qayyum , Jonas Richiardi , Antoine Saporta , Branislav Setlak , Ning Shen , Justin Szeto , Constantin Ulrich , Puru Vaish , Vibujithan Vigneshwaran , Leroy Volmer , Zihao Wang , Siqi Wei , Anthony Winder , Jelmer M. Wolterink , Maxence Wynen , Chang Yang , Si Young Yie , Mostafa Mehdipour Ghazi , Akshay Pai , Espen Jimenez Solem , Sebastian Nørgaard Llambias , Mikael Boesen , Michael Eriksen Benros , Juan Eugenio Iglesias , Mads Nielsen

The automatic diagnosis of Parkinson's disease is in high clinical demand due to its prevalence and the importance of targeted treatment. Current clinical practice often relies on diagnostic biomarkers in QSM and NM-MRI images. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Ding Shaodong , Liu Ziyang , Zhou Yijun , Liu Tao

Recently, vision-language representation learning has made remarkable advancements in building up medical foundation models, holding immense potential for transforming the landscape of clinical research and medical care. The underlying…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Weijian Huang , Cheng Li , Hao Yang , Jiarun Liu , Yong Liang , Hairong Zheng , Shanshan Wang

The field of computer vision is undergoing a paradigm shift toward large-scale foundation model pre-training via self-supervised learning (SSL). Leveraging large volumes of unlabeled brain MRI data, such models can learn anatomical priors…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Petros Koutsouvelis , Matej Gazda , Leroy Volmer , Sina Amirrajab , Kamil Barbierik , Branislav Setlak , Jakub Gazda , Peter Drotar

Current challenges in developing foundational models for volumetric imaging data, such as magnetic resonance imaging (MRI), stem from the computational complexity of training state-of-the-art architectures in high dimensions and curating…

Image and Video Processing · Electrical Eng. & Systems 2025-07-14 Ulzee An , Moonseong Jeong , Simon A. Lee , Aditya Gorla , Yuzhe Yang , Sriram Sankararaman

Small Language Models (SLMs) have shown remarkable performance in general domain language understanding, reasoning and coding tasks, but their capabilities in the medical domain, particularly concerning radiology text, is less explored. In…

Computation and Language · Computer Science 2024-03-18 Mercy Ranjit , Gopinath Ganapathy , Shaury Srivastav , Tanuja Ganu , Srujana Oruganti

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

X-ray imaging is a ubiquitous in radiology, yet most existing AI foundation models are limited to chest anatomy and fail to generalize across broader clinical tasks. In this work, we introduce XR-0, the multi-anatomy X-ray foundation model…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Nishank Singla , Krisztian Koos , Farzin Haddadpour , Amin Honarmandi Shandiz , Lovish Chum , Xiaojian Xu , Qing Jin , Erhan Bas

Foundation models are widely employed in medical image analysis, due to their high adaptability and generalizability for downstream tasks. With the increasing number of foundation models being released, model selection has become an…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Fuping Wu , Bartlomiej W. Papiez