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Quantum sensing with nitrogen-vacancy (NV) centers in diamond promises to revolutionize biological research and medical diagnostics. Thanks to their high sensitivity, NV sensors could, in principle, detect specific binding events with…

Optical properties of nanoparticles attract continuous attention owing to their high fundamental and applied importance across many disciplines. Recently emerged field of all-dielectric nanophotonics employs optically induced electric and…

Optics · Physics 2018-10-30 Roman E. Noskov , Ivan I. Shishkin , Hani Barhom , Pavel Ginzburg

Quantum biosensors offer a promising route to overcome the sensitivity and specificity limitations of conventional biosensing technologies. Their ability to detect biochemical signals at extremely low concentrations makes them strong…

Optics · Physics 2025-08-05 Yasaman Torabi , Shahram Shirani , James P. Reilly

Ultrasensitive optical detection of nanometer-scaled particles is highly desirable for applications in early-stage diagnosis of human diseases, environmental monitoring, and homeland security, but remains extremely difficult due to ultralow…

Imaging of the optical properties of individual nanosystems beyond fluorescence can provide a wealth of information. However, the minute signals for absorption and dispersion are challenging to observe, and only specialized techniques…

Optics · Physics 2015-09-10 Matthias Mader , Jakob Reichel , Theodor W. Hänsch , David Hunger

The possibility of using Nitrogen-vacancy centers in diamonds to measure nanoscale magnetic fields with unprecedented sensitivity is one of the most significant achievements of quantum sensing. Here we present an innovative experimental…

The height of dielectric metasurfaces is largely considered a constant in the fabrication process due to the top-down fabrication approach, resulting in a binary structure. Yet, for the recently introduced Mie voids metasurfaces,…

Optics · Physics 2026-03-31 Oren Goldberg , Noa Mazurski , Uriel Levy

We demonstrated a biosensing approach which, for the first time, combines the high-sensitivity of whispering gallery modes (WGM) with a metallic nanoparticle based assay. We provided a computational model based on generalized Mie theory to…

The characterization of individual nanoparticles in a liquid constitutes a critical challenge for environmental, material, and biological sciences. To detect nanoparticles, electronic approaches are especially desirable owing to their…

There is a growing need for biolabels that can be used in both optical and electron microscopies, are non-cytotoxic, and do not photobleach. Such biolabels could enable targeted nanoscale imaging of sub-cellular structures, and help to…

Biological Physics · Physics 2015-06-23 Mark A. Zurbuchen , Michael P. Lake , Sirus A. Kohan , Belinda Leung , Louis-S. Bouchard

All-dielectric resonant nanophotonics is a rapidly developing research field driven by its exceptional application potential for low-loss nanoscale metadevices. The tight confinement of the local electromagnetic fields and interferences in…

Optics · Physics 2018-10-26 Isabelle Staude , Thomas Pertsch , Yuri Kivshar

Dielectric nanoresonators have been shown to circumvent the heavy optical losses associated with plasmonic devices, however they suffer from less confined resonances. By constructing a hybrid system of both dielectric and metallic…

Benefitting from the excellent characteristics such as low cytotoxicity, functionalization versatility, and tunable fluorescence, nanodiamonds (NDs) have shown enormous application potentials in the biomedical field. Herein, we proposed,…

We report a method to measure the size of single dielectric nanoparticles with high accuracy and precision using quantitative differential interference contrast (DIC) microscopy. Dielectric nanoparticles are detected optically by the…

Nanophotonic concepts can improve many measurement techniques by enhancing and tailoring the light-matter interaction. However, the optical response of devices that implement such techniques can be intricate, depending on the sample under…

Nanoscale control of optical dispersion is essential for applications ranging from miniaturized spectrometers to color printing, all of which demand broadband spectral tunability. However, the Kramers-Kronig relations impose a fundamental…

The detection of quantal exocytic events from neurons and neuroendocrine cells is a challenging task in neuroscience. One of the most promising platforms for the development of a new generation of biosensors is diamond, due to its…

Instrumentation and Detectors · Physics 2016-08-30 F. Picollo , A. Battiato , E. Carbone , L. Croin , E. Enrico , J. Forneris , S. Gosso , P. Olivero , A. Pasquarelli , V. Carabelli

Label-free biosensors are important tools for clinical diagnostics and for studying biology at the single molecule level. The development of optical label-free sensors has allowed extreme sensitivity, but can expose the biological sample to…

Color centers in diamond provide a promising platform for quantum optics in the solid state, with coherent optical transitions and long-lived electron and nuclear spins. Building upon recent demonstrations of nanophotonic waveguides and…

Integrated nanophotonic biosensors offer a promising route toward future biomedical detection applications that may enable inexpensive, portable, and sensitive diagnosis of diseases with a small amount of biological samples for convenient…

Optics · Physics 2024-08-12 Ze-Lin Kong , Yang Liu , Jian-Hua Jiang