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Capturing biological specimens at large scales with sub-micron resolution is crucial for biomedical research, but conventional cameras often can't handle the pixel requirements. While most microscopes use motorized stages to move samples…

Optics · Physics 2025-03-28 Charlie Kersuzan , Aymerick Bazin , Amaury Badon

We demonstrate a neutron tomography technique with sub-micrometer spatial resolution. Our method consists of measuring neutron diffraction spectra using a double crystal diffractometer as a function of sample rotation and then using a phase…

Instrumentation and Detectors · Physics 2020-11-13 B. Heacock , D. Sarenac , D. G. Cory , M. G. Huber , J. P. W. MacLean , H. Miao , H. Wen , D. A. Pushin

Super-resolution microscopy has revolutionized the imaging of complex physical and biological systems by surpassing the Abbe diffraction limit. Recent advancements, particularly in single-molecule localization microscopy (SMLM), have pushed…

Stimulated Emission Depletion (STED) microscopy has emerged as a powerful technique providing visualization of biological structures at the molecular level in living samples. In this technique, the diffraction limit is broken by selectively…

We propose to use intensity correlation microscopy in combination with structured illumination to image quantum emitters that exhibit antibunching with a spatial resolution reaching far beyond the Rayleigh limit. Combining intensity…

Intra-operative measurements of tissue shape and multi/ hyperspectral information have the potential to provide surgical guidance and decision making support. We report an optical probe based system to combine sparse hyperspectral…

Computer Vision and Pattern Recognition · Computer Science 2017-06-22 Jianyu Lin , Neil T. Clancy , Yang Hu , Ji Qi , Taran Tatla , Danail Stoyanov , Lena Maier-Hein , Daniel S. Elson

In medical imaging, unsupervised out-of-distribution (OOD) detection offers an attractive approach for identifying pathological cases with extremely low incidence rates. In contrast to supervised methods, OOD-based approaches function…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Lemar Abdi , Francisco Caetano , Amaan Valiuddin , Christiaan Viviers , Hamdi Joudeh , Fons van der Sommen

While single-image super-resolution (SISR) has attracted substantial interest in recent years, the proposed approaches are limited to learning image priors in order to add high frequency details. In contrast, multi-frame super-resolution…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Goutam Bhat , Martin Danelljan , Luc Van Gool , Radu Timofte

Structured illumination microscopy (SIM) uses a set of images captured with different illumination patterns to computationally reconstruct resolution beyond the diffraction limit. Here, we propose an alternative approach using a single…

Optics · Physics 2025-06-17 Ruiming Cao , Guanghan Meng , Laura Waller

Radio frequency (RF) signals have been proved to be flexible for human silhouette segmentation (HSS) under complex environments. Existing studies are mainly based on a one-shot approach, which lacks a coherent projection ability from the RF…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Penghui Wen , Kun Hu , Dong Yuan , Zhiyuan Ning , Changyang Li , Zhiyong Wang

Recently it was reported that deeply subwavelength features of free space superoscillatory electromagnetic fields can be observed experimentally and used in optical metrology with nanoscale resolution [Science 364, 771 (2019)]. Here we…

Optics · Physics 2019-10-08 T. Pu , V. Savinov , G. Yuan , N. Papasimakis , N. I. Zheludev

Using scanning tunneling microscopy-induced luminescence (STML), the optical properties of two-dimensional (2D) semiconductors may be investigated at the nanoscale. This is possible because the tunneling current under the tip is an…

Magnetic Resonance Spectroscopic Imaging (MRSI) is a non-invasive imaging technique for studying metabolism and has become a crucial tool for understanding neurological diseases, cancers and diabetes. High spatial resolution MRSI is needed…

Image super-resolution (SR) has attracted increasing attention due to its wide applications. However, current SR methods generally suffer from over-smoothing and artifacts, and most work only with fixed magnifications. This paper introduces…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Sicheng Gao , Xuhui Liu , Bohan Zeng , Sheng Xu , Yanjing Li , Xiaoyan Luo , Jianzhuang Liu , Xiantong Zhen , Baochang Zhang

Ultrasound Localization Microscopy (ULM) enables imaging of vascular structures in the micrometer range by accumulating contrast agent particle locations over time. Precise and efficient target localization accuracy remains an active…

Image and Video Processing · Electrical Eng. & Systems 2023-11-08 Christopher Hahne , Georges Chabouh , Olivier Couture , Raphael Sznitman

Fourier Ptychographic Microscopy (FPM) is a computational imaging method that is able to super-resolve features beyond the diffraction-limit set by the objective lens of a traditional microscope. This is accomplished by using synthetic…

Signal Processing · Electrical Eng. & Systems 2019-04-09 Michael Kellman , Emrah Bostan , Michael Chen , Laura Waller

Remote sensing images captured by different platforms exhibit significant disparities in spatial resolution. Large scale factor super-resolution (SR) algorithms are vital for maximizing the utilization of low-resolution (LR) satellite data…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Ce Wang , Wanjie Sun

Accurate dose distribution prediction is crucial in the radiotherapy planning. Although previous methods based on convolutional neural network have shown promising performance, they have the problem of over-smoothing, leading to prediction…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Xin Liao , Zhenghao Feng , Jianghong Xiao , Xingchen Peng , Yan Wang

Fluorescence molecular tomography (FMT) is a sensitive optical imaging technology widely used in biomedical research. However, the ill-posedness of the inverse problem poses a huge challenge to FMT reconstruction. Although end-to-end deep…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Peng Zhang , Qianqian Xue , Xingyu Liu , Guanglei Zhang , Wenjian Wang , Jiye Liang

Structured illumination microscopy (SIM) is one of the most versatile super-resolution techniques. Yet, its application to live imaging has been so far mainly limited to fluorescent and stationary specimens. Here, we present advancements in…

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