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Parkinson's disease (PD) is a neurodegenerative disorder, manifesting with motor and non-motor symptoms. Depressive symptoms are prevalent in PD, affecting up to 45% of patients. They are often underdiagnosed due to overlapping motor…

Parkinson's disease (PD) is a neurodegenerative disease affecting about 1% of people over the age of 60, causing motor impairments that impede hand coordination activities such as writing and drawing. Many approaches have tried to support…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Mhd Adnan Albani , Riad Sonbol

Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…

Machine Learning · Computer Science 2025-04-25 Lorenzo Simone , Mauro Giuseppe Camporeale , Vito Marco Rubino , Vincenzo Gervasi , Giovanni Dimauro

A large scale computational model of the basal ganglia (BG) network is proposed to describes movement disorder including deep brain stimulation (DBS). The model of this complex network considers four areas of the basal ganglia network: the…

Neurons and Cognition · Quantitative Biology 2021-03-15 Konstantinos Spiliotis , Jens Starke , Denise Franz , Angelika Richter , Rüdiger Köhling

Accurate early diagnosis and monitoring of neurodegenerative conditions is essential for effective disease management and delivery of medication and treatment. This research develops automatic methods for detecting brain imaging preclinical…

Neural and Evolutionary Computing · Computer Science 2019-10-15 Amir Dehsarvi , Stephen L. Smith

In this work, we use a deep learning framework for simultaneous classification and regression of Parkinson disease diagnosis based on MR-Images and personal information (i.e. age, gender). We intend to facilitate and increase the confidence…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Soheil Esmaeilzadeh , Yao Yang , Ehsan Adeli

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

Neurons and Cognition · Quantitative Biology 2018-11-16 Patrick Schwab , Walter Karlen

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

Machine Learning · Computer Science 2019-04-26 Jann Goschenhofer , Franz MJ Pfister , Kamer Ali Yuksel , Bernd Bischl , Urban Fietzek , Janek Thomas

Parkinson's Disease(PD) is one of the major nervous system disorders that affect people over 60. PD can cause cognitive impairments. In this work, we explore various approaches to identify Parkinson's using Magnetic Resonance (MR) T1 images…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Tahjid Ashfaque Mostafa , Irene Cheng

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

Machine Learning · Computer Science 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang

Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from…

Machine Learning · Computer Science 2020-10-14 Jie Mei , Christian Desrosiers , Johannes Frasnelli

Parkinson's disease is a widespread neurodegenerative condition necessitating early diagnosis for effective intervention. This paper introduces an innovative method for diagnosing Parkinson's disease through the analysis of human EEG…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Maryam Allahbakhshi , Aylar Sadri , Seyed Omid Shahdi

Our brain is a complex information processing network in which the nervous system receives information from the environment to quickly react to incoming events or learns from experience to sharp our memory. In the nervous system, the brain…

Neurons and Cognition · Quantitative Biology 2022-06-20 Thi Kim Thoa Thieu , Roderick Melnik

People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring the progression of the disease through a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-05-25 Mohammadreza Iman , Amy Giuntini , Hamid Reza Arabnia , Khaled Rasheed

Detecting Parkinson's Disease in its early stages using EEG data presents a significant challenge. This paper introduces a novel approach, representing EEG data as a 15-variate series of bandpower and peak frequency values/coefficients. The…

Neurons and Cognition · Quantitative Biology 2023-12-11 Amarpal Sahota , Amber Roguski , Matthew W. Jones , Michal Rolinski , Alan Whone , Raul Santos-Rodriguez , Zahraa S. Abdallah

Parkinson's Disease (PD) is the second most common neurodegenerative disease in humans. PD is characterized by the gradual loss of dopaminergic neurons in the Substantia Nigra (SN). Counting the number of dopaminergic neurons in the SN is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Fatemeh Haghighi , Soumitra Ghosh , Hai Ngu , Sarah Chu , Han Lin , Mohsen Hejrati , Baris Bingol , Somaye Hashemifar

Parkinson's disease (PD) is a chronic neurodegenerative disease. It shows multiple motor symptoms such as tremor, bradykinesia, postural instability, freezing of gait (FoG). PD is currently diagnosed clinically through physical exam by…

Machine Learning · Computer Science 2026-04-21 Meheru Zannat

Parkinson's Disease (PD) medication management presents unique challenges due to heterogeneous disease progression and treatment response. Neurologists must balance symptom control with optimal dopaminergic dosing based on functional…

Machine Learning · Computer Science 2025-08-15 Ricardo Diaz-Rincon , Muxuan Liang , Adolfo Ramirez-Zamora , Benjamin Shickel

We present an artificial intelligence system to remotely assess the motor performance of individuals with Parkinson's disease (PD). Participants performed a motor task (i.e., tapping fingers) in front of a webcam, and data from 250 global…