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Large language models (LLMs) are increasingly adopted in medical question-answering (QA) scenarios. However, LLMs can generate hallucinations and nonfactual information, undermining their trustworthiness in high-stakes medical tasks.…

Computation and Language · Computer Science 2025-05-09 Yusong Ke , Hongru Lin , Yuting Ruan , Junya Tang , Li Li

This research addresses the challenge of conducting interpretable causal inference between a binary treatment and its resulting outcome when not all confounders are known. Confounders are factors that have an influence on both the treatment…

Machine Learning · Computer Science 2023-10-24 Sohaib Kiani , Jared Barton , Jon Sushinsky , Lynda Heimbach , Bo Luo

Generative artificial intelligence (AI) is a promising direction for augmenting clinical diagnostic decision support and reducing diagnostic errors, a leading contributor to medical errors. To further the development of clinical AI systems,…

Computation and Language · Computer Science 2023-06-14 Brihat Sharma , Yanjun Gao , Timothy Miller , Matthew M. Churpek , Majid Afshar , Dmitriy Dligach

Large language models (LLMs) struggle in real-world clinical consultations. Single-turn consultation systems require patients to describe all symptoms at once, which often leads to unclear complaints and vague diagnoses. Traditional…

Computation and Language · Computer Science 2026-05-01 Yichun Feng , Jiawei Wang , Lu Zhou , Yikai Zheng , Zhen Lei , Yixue Li

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

Computation and Language · Computer Science 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

Aligning the decision-making process of machine learning algorithms with that of experienced radiologists is crucial for reliable diagnosis. While existing methods have attempted to align their diagnosis behaviors to those of radiologists…

Machine Learning · Computer Science 2025-02-10 Mingzhou Liu , Ching-Wen Lee , Xinwei Sun , Yu Qiao , Yizhou Wang

Diagnosing hepatic diseases accurately and interpretably is critical, yet it remains challenging in real-world clinical settings. Existing AI approaches for clinical diagnosis often lack transparency, structured reasoning, and…

Artificial Intelligence · Computer Science 2026-03-06 Zheng Li , Jiayi Xu , Zhikai Hu , Hechang Chen , Lele Cong , Yunyun Wang , Shuchao Pang

Evaluating the clinical correctness and reasoning fidelity of automatically generated medical imaging reports remains a critical yet unresolved challenge. Existing evaluation methods often fail to capture the structured diagnostic logic…

Artificial Intelligence · Computer Science 2026-01-26 Suzhong Fu , Jingqi Dong , Xuan Ding , Rui Sun , Yiming Yang , Shuguang Cui , Zhen Li

Argument Mining (AM) is a foundational technology for automated writing evaluation, yet traditional supervised approaches rely heavily on expensive, domain-specific fine-tuning. While Large Language Models (LLMs) offer a training-free…

Computation and Language · Computer Science 2026-03-31 Jakub Bąba , Jarosław A. Chudziak

Clinical diagnosis requires sequential evidence acquisition under uncertainty. However, most Large Language Model (LLM) based diagnostic systems assume fully observed patient information and therefore do not explicitly model how clinical…

Artificial Intelligence · Computer Science 2026-04-08 Xuyang Shen , Haoran Liu , Dongjin Song , Martin Renqiang Min

Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

Computers and Society · Computer Science 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla

This research tests the role of Large Language Models (LLMs) as formal second opinion tools in professional decision-making, particularly focusing on complex medical cases where even experienced physicians seek peer consultation. The work…

Cryptography and Security · Computer Science 2024-10-29 David Noever

Large Language Models (LLMs) suffer from hallucinations and factual inaccuracies, especially in complex reasoning and fact verification tasks. Multi-Agent Debate (MAD) systems aim to improve answer accuracy by enabling multiple LLM agents…

Computation and Language · Computer Science 2026-01-09 Seyeon Jeong , Yeonjun Choi , JongWook Kim , Beakcheol Jang

Large language models (LLMs) enable waveform-to-text ECG interpretation and interactive clinical questioning, yet most ECG-LLM systems still rely on weak signal-text alignment and retrieval without explicit physiological or causal…

Large Language Models (LLMs) have transformed natural language processing and hold growing promise for advancing science, healthcare, and decision-making. Yet their training paradigms remain dominated by affirmation-based inference, akin to…

Artificial Intelligence · Computer Science 2025-12-05 Peter B. Walker , Hannah Davidson , Aiden Foster , Matthew Lienert , Thomas Pardue , Dale Russell

Medical decision-making often involves integrating knowledge from multiple clinical specialties, typically achieved through multidisciplinary teams. Inspired by this collaborative process, recent work has leveraged large language models…

Artificial Intelligence · Computer Science 2025-09-19 Xiao Wu , Ting-Zhu Huang , Liang-Jian Deng , Yanyuan Qiao , Imran Razzak , Yutong Xie

Real-world clinical diagnosis is a complex process in which the doctor is required to obtain information from both interaction with the patient and conducting medical exams. Additionally, the doctor needs to adapt to different patient…

Computation and Language · Computer Science 2026-05-11 Yicheng Gao , Xiaolin Zhou , Yahan Li , Yue Zhao , Ruishan Liu

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Causal reasoning and logical reasoning are two important types of reasoning abilities for human intelligence. However, their relationship has not been extensively explored under machine intelligence context. In this paper, we explore how…

Information Retrieval · Computer Science 2023-07-06 Jianchao Ji , Zelong Li , Shuyuan Xu , Max Xiong , Juntao Tan , Yingqiang Ge , Hao Wang , Yongfeng Zhang

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao