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Purpose: Multi-expert deep learning training methods to automatically quantify ischemic brain tissue on Non-Contrast CT Materials and Methods: The data set consisted of 260 Non-Contrast CTs from 233 patients of acute ischemic stroke…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Sophie Ostmeier , Brian Axelrod , Benjamin Pulli , Benjamin F. J. Verhaaren , Abdelkader Mahammedi , Yongkai Liu , Christian Federau , Greg Zaharchuk , Jeremy J. Heit

The extent of intra-individual and inter-individual variability is an important factor in determining the statistical, and hence possibly clinical, significance of observed differences in the EEG. This study investigates the changes in…

Neurons and Cognition · Quantitative Biology 2018-01-08 Sacha Jennifer van Albada , Christopher J. Rennie , Peter A. Robinson

Accurate assessment of Parkinsonian tremor is vital for monitoring disease progression and evaluating treatment efficacy. We introduce a pixel-based deep learning model designed to analyse postural tremor in Parkinson's disease (PD) from…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Felipe Duque-Quiceno , Grzegorz Sarapata , Yuriy Dushin , Miles Allen , Jonathan O'Keeffe

Perceived outcomes from DBS for PD were sampled for 52 cases by surveying 46 DBS recipients and 45 carers. Post-DBS experience ranged from 10-129 months. There were significant variations in perceived outcomes over time. In some cases…

Neurons and Cognition · Quantitative Biology 2015-08-11 N. W. Page , C. Hall , S. D. Page

Multi-electrode arrays (MEA) are increasingly used to investigate spontaneous neuronal network activity. The recorded signals comprise several distinct components: Apart from artefacts without biological significance, one can distinguish…

Neurons and Cognition · Quantitative Biology 2017-04-03 Måns Henningson , Sebastian Illes

Automated segmentation and volumetry of brain magnetic resonance imaging (MRI) scans are essential for the diagnosis of Parkinson's disease (PD) and Parkinson's plus syndromes (P-plus). To enhance the diagnostic performance, we adopt deep…

Image and Video Processing · Electrical Eng. & Systems 2022-07-26 Joomee Song , Juyoung Hahm , Jisoo Lee , Chae Yeon Lim , Myung Jin Chung , Jinyoung Youn , Jin Whan Cho , Jong Hyeon Ahn , Kyung-Su Kim

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

Signal Processing · Electrical Eng. & Systems 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

Decoherence between qubits is a major bottleneck in quantum computations. Decoherence results from intrinsic quantum and thermal fluctuations as well as noise in the external fields that perform the measurement and preparation processes.…

Quantum Physics · Physics 2024-07-17 Ryan T. Grimm , Joel D. Eaves

In a recent paper, cond-mat/0405331 (Ref. 1), del Barco et al. reported experimental studies on a Ni4 molecular system. They used an experimental method (combining microwave spectroscopy with high sensitivity magnetic measurements) that we…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 W. Wernsdorfer

Magnetoencephalographic (MEG) recordings from a large normative cohort (n = 619) were processed to extract measures of regional neuroelectric activity. The overall objective of the effort was to use these measures to identify normative…

Neurons and Cognition · Quantitative Biology 2018-11-20 Don Krieger , Paul Shepard , David O. Okonkwo

Segmenting stroke lesions in MRI is challenging due to diverse acquisition protocols that limit model generalisability. In this work, we introduce two physics-constrained approaches to generate synthetic quantitative MRI (qMRI) images that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

The analysis of electrophysiological data is crucial for certain surgical procedures such as deep brain stimulation, which has been adopted for the treatment of a variety of neurological disorders. During the procedure, auditory analysis of…

Machine Learning · Computer Science 2025-03-24 Thibault Martin , Paul Sauleau , Claire Haegelen , Pierre Jannin , John S. H. Baxter

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

Methodology · Statistics 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Parkinson's disease (PD) is a highly heterogeneous disease, including which motor symptoms are dominating. Imaging biomarkers that support subtype stratification could also improve biological understanding and study design, and enable…

Recordings of electrical brain activity carry information about a person's cognitive health. For recording EEG signals, a very common setting is for a subject to be at rest with its eyes closed. Analysis of these recordings often involve a…

Neurons and Cognition · Quantitative Biology 2018-12-18 Sebastian Mathias Keller , Maxim Samarin , Antonia Meyer , Vitalii Kosak , Ute Gschwandtner , Peter Fuhr , Volker Roth

Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the…

Neurons and Cognition · Quantitative Biology 2013-02-11 Choongseok Park , Leonid Rubchinsky

Parkinsons disease, PD, is a chronic condition that affects motor skills and includes symptoms like tremors and rigidity. The current diagnostic procedure uses patient assessments to evaluate symptoms and sometimes a magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Sabrina Zhu

This thesis delves into the world of non-invasive electrophysiological brain signals like electroencephalography (EEG) and magnetoencephalography (MEG), focusing on modelling and decoding such data. The research aims to investigate what…

Signal Processing · Electrical Eng. & Systems 2025-10-30 Richard Csaky

A transversal study of the pitch variability of parkinsonian voices in read speech is presented. 30 patients suffering from Parkinson's disease (PD) and 32 healthy speakers were recorded while reading a text without voiceless phonemes. The…

Audio and Speech Processing · Electrical Eng. & Systems 2024-02-12 Pablo Rodriguez-Perez , Ruben Fraile , Miguel Garcia-Escrig , Nicolas Saenz-Lechon , Juana M. Gutierrez-Arriola , Victor Osma-Ruiz

Regular and stochastic behavior in the time series of Parkinsonian pathological tremor velocity is studied on the basis of the statistical theory of discrete non-Markov stochastic processes and flicker-noise spectroscopy. We have developed…