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Physics-informed neural networks (PINNs) have recently received much attention due to their capabilities in solving both forward and inverse problems. For training a deep neural network associated with a PINN, one typically constructs a…

Machine Learning · Computer Science 2022-08-26 Pouyan Nasiri , Roozbeh Dargazany

Inferring biophysical parameters and hidden state variables from partial and noisy observations is a fundamental challenge in computational neuroscience. This problem is particularly difficult for fast - slow spiking and bursting models,…

Neural and Evolutionary Computing · Computer Science 2026-03-11 Changliang Wei , Yangyang Wang , Xueyu Zhu

Partial differential equations (PDEs) are central to scientific modeling. Modern workflows increasingly rely on learning-based components to support model reuse, inference, and integration across large computational processes. Despite the…

Machine Learning · Computer Science 2026-02-20 Yilong Dai , Shengyu Chen , Ziyi Wang , Xiaowei Jia , Yiqun Xie , Vipin Kumar , Runlong Yu

Physics-informed neural networks (PINNs) are effective in solving integer-order partial differential equations (PDEs) based on scattered and noisy data. PINNs employ standard feedforward neural networks (NNs) with the PDEs explicitly…

Computational Physics · Physics 2021-11-03 Guofei Pang , Lu Lu , George Em Karniadakis

Physics informed neural networks (PINNs) are nowadays used as efficient machine learning methods for solving differential equations. However, vanilla-PINNs fail to learn complex problems as ones involving stiff ordinary differential…

Computational Physics · Physics 2023-04-18 Hubert Baty

Physics-informed neural networks (PINNs) have emerged as a promising deep learning method, capable of solving forward and inverse problems governed by differential equations. Despite their recent advance, it is widely acknowledged that…

Machine Learning · Computer Science 2024-06-11 Franz M. Rohrhofer , Stefan Posch , Clemens Gößnitzer , Bernhard C. Geiger

Physics-Informed Neural Networks (PINNs) represent a groundbreaking paradigm in scientific computing, seamlessly integrating the robust framework of deep learning with fundamental physical laws. This paper meticulously applies the standard…

Numerical Analysis · Mathematics 2026-01-19 Ahmed Aberqi , Ahmed Miloudi

Physics-informed machine learning (PIML) is emerging as a potentially transformative paradigm for modeling complex biomedical systems by integrating parameterized physical laws with data-driven methods. Here, we review three main classes of…

Machine Learning · Computer Science 2025-10-08 Nazanin Ahmadi , Qianying Cao , Jay D. Humphrey , George Em Karniadakis

Physics-informed neural networks (PINNs) and their variants have been very popular in recent years as algorithms for the numerical simulation of both forward and inverse problems for partial differential equations. This article aims to…

Numerical Analysis · Mathematics 2024-11-20 Tim De Ryck , Siddhartha Mishra

In this study, we explore the application of Physics-Informed Neural Networks (PINNs) to the analysis of bifurcation phenomena in ecological migration models. By integrating the fundamental principles of diffusion-advection-reaction…

Chaotic Dynamics · Physics 2025-11-25 Lujie Yin , Xing Lv

Physics-informed neural networks (PINNs) [31] use automatic differentiation to solve partial differential equations (PDEs) by penalizing the PDE in the loss function at a random set of points in the domain of interest. Here, we develop a…

Neural and Evolutionary Computing · Computer Science 2019-12-03 E. Kharazmi , Z. Zhang , G. E. Karniadakis

This dissertation investigates physics-informed neural networks (PINNs) as candidate models for encoding governing equations, and assesses their performance on experimental data from two different systems. The first system is a simple…

Machine Learning · Computer Science 2024-01-09 Hamza Alsharif

Physics-informed neural networks (PINNs) have been proven as a promising way for solving various partial differential equations, especially high-dimensional ones and those with irregular boundaries. However, their capabilities in real…

Dynamical Systems · Mathematics 2026-03-27 Guojie Li , Wuyue Yang , Liu Hong

We study the problem of learning neural network models for Ordinary Differential Equations (ODEs) with parametric uncertainties. Such neural network models capture the solution to the ODE over a given set of parameters, initial conditions,…

Machine Learning · Computer Science 2025-07-31 Chandra Kanth Nagesh , Sriram Sankaranarayanan , Ramneet Kaur , Tuhin Sahai , Susmit Jha

Machine learning techniques have recently been of great interest for solving differential equations. Training these models is classically a data-fitting task, but knowledge of the expression of the differential equation can be used to…

Dynamical Systems · Mathematics 2024-07-26 James H. Adler , Samuel Hocking , Xiaozhe Hu , Shafiqul Islam

Physics-informed neural networks (PINNs) provide a powerful framework for learning governing equations of dynamical systems from data. Biologically-informed neural networks (BINNs) are a variant of PINNs that preserve the known differential…

Machine Learning · Computer Science 2026-04-21 William Lavery , Jodie A. Cochrane , Christian Olesen , Dagim S. Tadele , John T. Nardini , Sara Hamis

Partial differential equations (PDEs) serve as the cornerstone of mathematical physics. In recent years, Physics-Informed Neural Networks (PINNs) have significantly reduced the dependence on large datasets by embedding physical laws…

Machine Learning · Computer Science 2025-06-09 Wenxuan Huo , Qiang He , Gang Zhu , Weifeng Huang

Physics-informed neural networks (PINNs) have recently been used to solve various computational problems which are governed by partial differential equations (PDEs). In this paper, we propose a multi-output physics-informed neural network…

Computational Engineering, Finance, and Science · Computer Science 2022-12-07 Mingyuan Yang , John T. Foster

Physics-informed neural networks (PINNs) are a newly emerging research frontier in machine learning, which incorporate certain physical laws that govern a given data set, e.g., those described by partial differential equations (PDEs), into…

Neural and Evolutionary Computing · Computer Science 2023-07-11 Bo Wang , A. K. Qin , Sajjad Shafiei , Hussein Dia , Adriana-Simona Mihaita , Hanna Grzybowska

We present a unified theoretical framework for analyzing the stability and consistency of Physics-Informed Neural Networks (PINNs), grounded in operator coercivity, variational formulations, and non-asymptotic perturbation theory. PINNs…

Machine Learning · Computer Science 2025-09-04 Ronald Katende