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Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

Computational Complexity · Computer Science 2025-02-11 Md Romizul Islam , Swakkhar Shatabda

Remote sensing pansharpening aims to reconstruct spatial-spectral properties during the fusion of panchromatic (PAN) images and low-resolution multi-spectral (LR-MS) images, finally generating the high-resolution multi-spectral (HR-MS)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Mengting Ma , Yizhen Jiang , Mengjiao Zhao , Jiaxin Li , Wei Zhang

High-dimensional single-cell data poses significant challenges in identifying underlying biological patterns due to the complexity and heterogeneity of cellular states. We propose a comprehensive gene-cell dependency visualization via…

Machine Learning · Computer Science 2024-07-25 Shang-Jung Wen , Jia-Ming Chang , Fang Yu

We introduce a novel ensemble approach for feature selection based on hierarchical stacking for non-stationarity and/or a limited number of samples with a large number of features. Our approach exploits the co-dependency between features…

Machine Learning · Computer Science 2024-10-08 Aysin Tumay , Mustafa E. Aydin , Ali T. Koc , Suleyman S. Kozat

Network embedding (NE) approaches have emerged as a predominant technique to represent complex networks and have benefited numerous tasks. However, most NE approaches rely on a homophily assumption to learn embeddings with the guidance of…

Social and Information Networks · Computer Science 2022-12-23 Zhiqiang Zhong , Guadalupe Gonzalez , Daniele Grattarola , Jun Pang

Single-cell RNA sequencing (scRNA-seq) technologies have enabled the profiling of gene expression for a collection of cells across time during a dynamic biological process. Given that each time point provides only a static snapshot,…

Applications · Statistics 2025-06-16 Binghao Yan , Hongzhe Li

Recently various types of topological Laplacians have been studied from the perspective of data analysis. The spectral theory of these Laplacians has significantly extended the scope of algebraic topology and data analysis. Inspired by the…

Algebraic Topology · Mathematics 2023-12-06 Xiaoqi Wei , Guo-Wei Wei

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data.…

Machine Learning · Computer Science 2024-11-28 Huifa Li , Jie Fu , Xinpeng Ling , Zhiyu Sun , Kuncan Wang , Zhili Chen

Heterogeneous information network (HIN) embedding has recently attracted much attention due to its effectiveness in dealing with the complex heterogeneous data. Meta path, which connects different object types with various semantic…

Social and Information Networks · Computer Science 2019-05-15 Sheng Zhou , Jiajun Bu , Xin Wang , Jiawei Chen , Can Wang

Single-cell transcriptomics enabled the study of cellular heterogeneity in response to perturbations at the resolution of individual cells. However, scaling high-throughput screens (HTSs) to measure cellular responses for many drugs remains…

Machine Learning · Computer Science 2023-01-03 Leon Hetzel , Simon Böhm , Niki Kilbertus , Stephan Günnemann , Mohammad Lotfollahi , Fabian Theis

Single-cell RNA sequencing (scRNA-seq) is a relatively new technology that has stimulated enormous interest in statistics, data science, and computational biology due to the high dimensionality, complexity, and large scale associated with…

Machine Learning · Statistics 2023-10-25 Yuta Hozumi , Guo-Wei Wei

A recently developed upscaling technique, the multicontinuum homogenization method, has gained significant attention for its effectiveness in modeling complex multiscale systems. This method defines multiple continua based on distinct…

Numerical Analysis · Mathematics 2025-12-24 Wei Xie , Viet Ha Hoang , Yin Yang , Yunqing Huang

Incorporating heterogeneous representations from different architectures has facilitated various vision tasks, e.g., some hybrid networks combine transformers and convolutions. However, complementarity between such heterogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Zhong-Yu Li , Bo-Wen Yin , Yongxiang Liu , Li Liu , Ming-Ming Cheng

Graphs with heterophily, where adjacent nodes carry different labels, are prevalent in real-world applications, from social networks to molecular interactions. However, existing spectral Graph Neural Network (GNN) approaches tailored for…

Machine Learning · Computer Science 2026-05-13 Md Sazzad Hossen , Avimanyu Sahoo

Spectral clustering is a key research topic in the field of machine learning and data mining. Most of the existing spectral clustering algorithms are built upon Gaussian Laplacian matrices, which are sensitive to parameters. We propose a…

Machine Learning · Computer Science 2015-10-07 Xiaojun Chang , Feiping Nie , Yi Yang , Heng Huang

The joint optimization of representation learning and clustering in the embedding space has experienced a breakthrough in recent years. In spite of the advance, clustering with representation learning has been limited to flat-level…

Machine Learning · Computer Science 2019-03-26 Su-Jin Shin , Kyungwoo Song , Il-Chul Moon

Inference in deep neural networks can be computationally expensive, and networks capable of anytime inference are important in mscenarios where the amount of compute or quantity of input data varies over time. In such networks the inference…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Adria Ruiz , Jakob Verbeek

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

In this paper, a hierarchical attention network to generate utterance-level embeddings (H-vectors) for speaker identification is proposed. Since different parts of an utterance may have different contributions to speaker identities, the use…

Computation and Language · Computer Science 2019-10-22 Yanpei Shi , Qiang Huang , Thomas Hain

Combinatorial and topological structures, such as graphs, simplicial complexes, and cell complexes, form the foundation of geometric and topological deep learning (GDL and TDL) architectures. These models aggregate signals over such…

Machine Learning · Computer Science 2026-05-28 Chuan-Shen Hu
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