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Convolutional Neural Networks (CNN) have been regarded as a powerful class of models for visual recognition problems. Nevertheless, the convolutional filters in these networks are local operations while ignoring the large-range dependency.…
Advances in spatial transcriptomics (ST) technologies enable systematic molecular characterization of tumor microenvironment, tumor gradients and gene regulatory networks. Cancer progression is known to vary along pathological gradients,…
Although spatio-temporal graph neural networks have achieved great empirical success in handling multiple correlated time series, they may be impractical in some real-world scenarios due to a lack of sufficient high-quality training data.…
Medical image segmentation requires balancing local precision for boundary-critical clinical applications, global context for anatomical coherence, and computational efficiency for deployment on limited data and hardware a trilemma that…
Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…
The early diagnosis and screening of glaucoma are important for patients to receive treatment in time and maintain eyesight. Nowadays, deep learning (DL) based models have been successfully used for computer-aided diagnosis (CAD) of…
We present SDXL, a latent diffusion model for text-to-image synthesis. Compared to previous versions of Stable Diffusion, SDXL leverages a three times larger UNet backbone: The increase of model parameters is mainly due to more attention…
Text-to-image generation has witnessed significant progress with the advent of diffusion models. Despite the ability to generate photorealistic images, current text-to-image diffusion models still often struggle to accurately interpret and…
Generative models have demonstrated strong performance in conditional settings and can be viewed as a form of data compression, where the condition serves as a compact representation. However, their limited controllability and…
Advanced diffusion-based Text-to-Image (T2I) models, such as the Stable Diffusion Model, have made significant progress in generating diverse and high-quality images using text prompts alone. However, when non-famous users require…
Efficiently capturing the complex spatiotemporal representations from large-scale unlabeled traffic data remains to be a challenging task. In considering of the dilemma, this work employs the advanced contrastive learning and proposes a…
Spatio-Temporal predictive Learning is a self-supervised learning paradigm that enables models to identify spatial and temporal patterns by predicting future frames based on past frames. Traditional methods, which use recurrent neural…
Advances in spatially-resolved transcriptomics (SRT) technologies have propelled the development of new computational analysis methods to unlock biological insights. As the cost of generating these data decreases, these technologies provide…
Spatial transcriptomics provides a molecularly rich description of tissue organization, enabling unsupervised discovery of tissue niches -- spatially coherent regions of distinct cell-type composition and function that are relevant to both…
Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…
In layout-to-image (L2I) synthesis, controlled complex scenes are generated from coarse information like bounding boxes. Such a task is exciting to many downstream applications because the input layouts offer strong guidance to the…
With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…
The advancements in generative modeling, particularly the advent of diffusion models, have sparked a fundamental question: how can these models be effectively used for discriminative tasks? In this work, we find that generative models can…
Scanning tunnelling microscopy (STM) enables atomic-resolution imaging and atom manipulation, but its utility is often limited by tip degradation and slow serial data acquisition. Fabrication adds another layer of complexity since the tip…
Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…