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The field of neuromorphic computing has gained significant attention in recent years, aiming to bridge the gap between the efficiency of biological neural networks and the performance of artificial intelligence systems. This paper…

Neural and Evolutionary Computing · Computer Science 2024-08-23 Jiahao Qin , Feng Liu

This paper introduces Bio-Inspired Mamba (BIM), a novel online learning framework for selective state space models that integrates biological learning principles with the Mamba architecture. BIM combines Real-Time Recurrent Learning (RTRL)…

Neural and Evolutionary Computing · Computer Science 2024-09-18 Jiahao Qin

Image generation models have encountered challenges related to scalability and quadratic complexity, primarily due to the reliance on Transformer-based backbones. In this study, we introduce MaskMamba, a novel hybrid model that combines…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Wenchao Chen , Liqiang Niu , Ziyao Lu , Fandong Meng , Jie Zhou

Protein function prediction is a pivotal task in drug discovery, significantly impacting the development of effective and safe therapeutics. Traditional machine learning models often struggle with the complexity and variability inherent in…

Machine Learning · Computer Science 2024-09-24 Bohao Xu , Yingzhou Lu , Yoshitaka Inoue , Namkyeong Lee , Tianfan Fu , Jintai Chen

Recent advances in multimodal learning have significantly improved cancer survival risk prediction. However, the joint prognostic potential of protein markers and histopathology images remains underexplored, largely due to the high cost and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Jing Dai , Chen Wu , Ming Wu , Qibin Zhang , Zexi Wu , Jingdong Zhang , Hongming Xu

The typical Selective State-Space Model (SSM) used in Mamba addresses several limitations of Transformers, such as the quadratic computational complexity with respect to sequence length and the significant memory requirements during…

Computation and Language · Computer Science 2025-10-24 Shengkun Tang , Liqun Ma , Haonan Li , Mingjie Sun , Zhiqiang Shen

We introduce a generative model for protein backbone design utilizing geometric products and higher order message passing. In particular, we propose Clifford Frame Attention (CFA), an extension of the invariant point attention (IPA)…

Machine Learning · Computer Science 2024-11-11 Simon Wagner , Leif Seute , Vsevolod Viliuga , Nicolas Wolf , Frauke Gräter , Jan Stühmer

Foundation models, now powering most of the exciting applications in deep learning, are almost universally based on the Transformer architecture and its core attention module. Many subquadratic-time architectures such as linear attention,…

Machine Learning · Computer Science 2024-06-03 Albert Gu , Tri Dao

Accurate chemical kinetics modeling is essential for combustion simulations, as it governs the evolution of complex reaction pathways and thermochemical states. In this work, we introduce Kinetic-Mamba, a Mamba-based neural operator…

Machine Learning · Computer Science 2026-04-07 Additi Pandey , Liang Wei , Hessam Babaee , George Em Karniadakis

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yanhua Zhang , Ke Zhang , Jingyu Wang , Gabriella Balestra , Samanta Rosati , Yulin Wu , Wuwei Wang , Valentina Giannini

Physical field reconstruction (PFR) aims to predict the state distribution of physical quantities (e.g., velocity, pressure, and temperature) based on limited sensor measurements. It plays a critical role in domains such as fluid dynamics…

Machine Learning · Computer Science 2025-05-23 Jiahuan Long , Wenzhe Zhang , Ning Wang , Tingsong Jiang , Wen Yao

With the evolution of large language models, traditional Transformer models become computationally demanding for lengthy sequences due to the quadratic growth in computation with respect to the sequence length. Mamba, emerging as a…

Machine Learning · Computer Science 2024-08-22 Haoran Xu , Ziqian Liu , Rong Fu , Zhongling Su , Zerui Wang , Zheng Cai , Zhilin Pei , Xingcheng Zhang

Infrared Image Super-Resolution (IRSR) is challenged by the low contrast and sparse textures of infrared data, requiring robust long-range modeling to maintain global coherence. While State-Space Models like Mamba offer proficiency in…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Yongsong Huang , Tomo Miyazaki , Xiaofeng Liu , Shinichiro Omachi

Recent advancements in unified multimodal understanding and visual generation (or multimodal generation) models have been hindered by their quadratic computational complexity and dependence on large-scale training data. We present…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Jialv Zou , Bencheng Liao , Qian Zhang , Wenyu Liu , Xinggang Wang

Protein-protein docking tools help in studying interactions between proteins, and are essential for drug, vaccine, and therapeutic development. However, the accuracy of a docking tool depends on a robust scoring function that can reliably…

Machine Learning · Computer Science 2025-10-21 Azam Shirali , Giri Narasimhan

Mamba, a recently proposed linear-time sequence model, has attracted significant attention for its computational efficiency and strong empirical performance. However, a rigorous theoretical understanding of its underlying mechanisms remains…

Machine Learning · Computer Science 2026-02-13 Junsoo Oh , Wei Huang , Taiji Suzuki

Reconstructing high-fidelity MR images from undersampled k-space data remains a challenging problem in MRI. While Mamba variants for vision tasks offer promising long-range modeling capabilities with linear-time complexity, their direct…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Hongli Chen , Pengcheng Fang , Yuxia Chen , Yingxuan Ren , Jing Hao , Fangfang Tang , Xiaohao Cai , Shanshan Shan , Feng Liu

Meta-learning facilitates few-shot hyperspectral target detection (HTD), but adapting deep backbones remains challenging. Full-parameter fine-tuning is inefficient and prone to overfitting, and existing methods largely ignore the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Luqi Gong , Qixin Xie , Yue Chen , Ziqiang Chen , Fanda Fan , Shuai Zhao , Chao Li

Human-human interaction generation has garnered significant attention in motion synthesis due to its vital role in understanding humans as social beings. However, existing methods typically rely on transformer-based architectures, which…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Zizhao Wu , Yingying Sun , Yiming Chen , Xiaoling Gu , Ruyu Liu , Jiazhou Chen

Mamba has recently gained widespread attention as a backbone model for point cloud modeling, leveraging a state-space architecture that enables efficient global sequence modeling with linear complexity. However, its lack of local inductive…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Xuanyu Lin , Xiaona Zeng , Xianwei Zheng , Xutao Li
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