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Mixed-integer linear programs (MILPs) are widely used in artificial intelligence and operations research to model complex decision problems like scheduling and routing. Designing such programs however requires both domain and modelling…

Artificial Intelligence · Computer Science 2021-07-16 Mohit Kumar , Samuel Kolb , Luc De Raedt , Stefano Teso

We consider {\em Mixed Linear Regression (MLR)}, where training data have been generated from a mixture of distinct linear models (or clusters) and we seek to identify the corresponding coefficient vectors. We introduce a {\em Mixed Integer…

Machine Learning · Statistics 2019-09-10 Taiyao Wang , Ioannis Ch. Paschalidis

This paper presents an algorithmic study of a class of covering mixed-integer linear programming problems which encompasses classic cover problems, including multidimensional knapsack, facility location and supplier selection problems. We…

Data Structures and Algorithms · Computer Science 2026-02-12 Kobe Grobben , Phablo F. S. Moura , Hande Yaman

Mixed-integer linear programming (MILP), a widely used modeling framework for combinatorial optimization, are central to many scientific and engineering applications, yet remains computationally challenging at scale. Recent advances in deep…

Artificial Intelligence · Computer Science 2026-01-09 Peixin Huang , Yaoxin Wu , Yining Ma , Cathy Wu , Wen Song , Wei Zhang

In this paper, we describe a comprehensive algorithmic framework for solving mixed integer bilevel linear optimization problems (MIBLPs) using a generalized branch-and-cut approach. The framework presented merges features from existing…

Optimization and Control · Mathematics 2021-04-20 Sahar Tahernejad , Ted K. Ralphs , Scott T. DeNegre

Over the past few decades, neuroscience experiments have become increasingly complex and naturalistic. Experimental design has in turn become more challenging, as experiments must conform to an ever-increasing diversity of design…

Neurons and Cognition · Quantitative Biology 2020-12-07 Storm Slivkoff , Jack L. Gallant

We consider the problem of learning optimal binary classification trees. Literature on the topic has burgeoned in recent years, motivated both by the empirical suboptimality of heuristic approaches and the tremendous improvements in…

Machine Learning · Statistics 2020-05-14 Sina Aghaei , Andres Gomez , Phebe Vayanos

While mixed-integer linear programming and convex programming solvers have advanced significantly over the past several decades, solution technologies for general mixed-integer nonlinear programs (MINLPs) have yet to reach the same level of…

Optimization and Control · Mathematics 2026-04-07 Danial Davarnia , Mohammadreza Kiaghadi , Junyuan Qiu

In this work, multi-step traffic predictions are leveraged to enable multi-period planning in reconfigurable optical networks. The proposed framework aims to achieve spectrum savings by adapting the network to predicted time-varying…

Networking and Internet Architecture · Computer Science 2026-05-26 Giannis Savva , Hafsa Maryam , Venkatesh Chebolu , Tania Panayiotou , Georgios Ellinas

Mixed integer convex and nonlinear programs, MICP and MINLP, are expressive but require long solving times. Recent work that combines data-driven methods on solver heuristics has shown potential to overcome this issue allowing for…

Optimization and Control · Mathematics 2022-08-30 Xuan Lin , Gabriel I. Fernandez , Dennis W. Hong

We establish a broad methodological foundation for mixed-integer optimization with learned constraints. We propose an end-to-end pipeline for data-driven decision making in which constraints and objectives are directly learned from data…

Optimization and Control · Mathematics 2023-10-30 Donato Maragno , Holly Wiberg , Dimitris Bertsimas , S. Ilker Birbil , Dick den Hertog , Adejuyigbe Fajemisin

Recent advances in mathematical programming have made Mixed Integer Optimization a competitive alternative to popular regularization methods for selecting features in regression problems. The approach exhibits unquestionable foundational…

Methodology · Statistics 2019-10-01 Ana Kenney , Francesca Chiaromonte , Giovanni Felici

Strategic bidding problems in electricity markets are widely studied in power systems, often by formulating complex bi-level optimization problems that are hard to solve. The state-of-the-art approach to solve such problems is to…

Optimization and Control · Mathematics 2016-06-21 Mahdi Ghamkhari , Ashkan Sadeghi-Mobarakeh , Hamed Mohsenian-Rad

In B2B markets, value-based pricing and selling has become an important alternative to discounting. This study outlines a modeling method that uses customer data (product offers made to each current or potential customer, features,…

Econometrics · Economics 2023-08-16 John V. Colias , Stella Park , Elizabeth Horn

Mixed-Integer Linear Programming (MILP) is a powerful framework used to address a wide range of NP-hard combinatorial optimization problems, often solved by Branch and Bound (B&B). A key factor influencing the performance of B&B solvers is…

Machine Learning · Computer Science 2025-10-23 Paul Strang , Zacharie Alès , Côme Bissuel , Olivier Juan , Safia Kedad-Sidhoum , Emmanuel Rachelson

The use of Mixed-Integer Linear Programming (MILP) models to represent neural networks with Rectified Linear Unit (ReLU) activations has become increasingly widespread in the last decade. This has enabled the use of MILP technology to…

Optimization and Control · Mathematics 2024-02-01 Fabian Badilla , Marcos Goycoolea , Gonzalo Muñoz , Thiago Serra

In many operational contexts, solutions to NP-hard combinatorial optimization problems, modeled by means of Mixed-Integer Linear Programming (MILP), may become infeasible due to unpredictable disruptions. Typically, reoptimizing by solving…

Optimization and Control · Mathematics 2026-05-27 Mathieu Lerouge , Andrea Lodi , Enrico Malaguti , Michele Monaci , Filippo Focacci

Mixed integer linear programming (MILP) solvers expose hundreds of parameters that have an outsized impact on performance but are difficult to configure for all but expert users. Existing machine learning (ML) approaches require training on…

Machine Learning · Computer Science 2025-09-25 Connor Lawless , Yingxi Li , Anders Wikum , Madeleine Udell , Ellen Vitercik

The analysis of infeasible subproblems plays an import role in solving mixed integer programs (MIPs) and is implemented in most major MIP solvers. There are two fundamentally different concepts to generate valid global constraints from…

Optimization and Control · Mathematics 2016-11-24 Jakob Witzig , Timo Berthold , Stefan Heinz

In this paper we provide a computation algorithm to get a global solution for the maximum rank correlation estimator using the mixed integer programming (MIP) approach. We construct a new constrained optimization problem by transforming all…

Econometrics · Economics 2022-08-11 Youngki Shin , Zvezdomir Todorov