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Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

Today's strongest video-language models (VLMs) remain proprietary. The strongest open-weight models either rely on synthetic data from proprietary VLMs, effectively distilling from them, or do not disclose their training data or recipe. As…

Recently, histopathology vision-language foundation models (VLMs) have gained popularity due to their enhanced performance and generalizability across different downstream tasks. However, most existing histopathology benchmarks are either…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Roba Al Majzoub , Hashmat Malik , Muzammal Naseer , Zaigham Zaheer , Tariq Mahmood , Salman Khan , Fahad Khan

Large Vision-Language Models (LVLMs) have recently played a dominant role in multimodal vision-language learning. Despite the great success, it lacks a holistic evaluation of their efficacy. This paper presents a comprehensive evaluation of…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Peng Xu , Wenqi Shao , Kaipeng Zhang , Peng Gao , Shuo Liu , Meng Lei , Fanqing Meng , Siyuan Huang , Yu Qiao , Ping Luo

Recent advancements in Vision Language Models (VLMs) have demonstrated remarkable promise in generating visually grounded responses. However, their application in the medical domain is hindered by unique challenges. For instance, most VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Lingxiao Luo , Bingda Tang , Xuanzhong Chen , Rong Han , Ting Chen

Vision-language models (VLMs) have demonstrated remarkable performance across a wide range of computer-vision tasks, sparking interest in their potential for digital health applications. Here, we apply VLMs to two fundamental challenges in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Victor Li , Naveenraj Kamalakannan , Avinash Parnandi , Heidi Schambra , Carlos Fernandez-Granda

Multimodal Large Language Models (MLLMs) have become a powerful tool for integrating visual and textual information. Despite their exceptional performance on visual understanding benchmarks, measuring their ability to reason abstractly…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Nilay Yilmaz , Maitreya Patel , Yiran Lawrence Luo , Tejas Gokhale , Chitta Baral , Suren Jayasuriya , Yezhou Yang

Real-world clinical decision-making requires integrating heterogeneous data, including medical text, 2D images, 3D volumes, and videos, while existing AI systems fail to unify all these signals, limiting their utility. In this paper, we…

Several recent works seek to develop foundation models specifically for medical applications, adapting general-purpose large language models (LLMs) and vision-language models (VLMs) via continued pretraining on publicly available biomedical…

Computation and Language · Computer Science 2024-11-21 Daniel P. Jeong , Saurabh Garg , Zachary C. Lipton , Michael Oberst

Modular vision-language models (Vision-LLMs) align pretrained image encoders with (frozen) large language models (LLMs) and post-hoc condition LLMs to `understand' the image input. With the abundance of readily available high-quality…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Gregor Geigle , Abhay Jain , Radu Timofte , Goran Glavaš

Vision-language modeling (VLM) aims to bridge the information gap between images and natural language. Under the new paradigm of first pre-training on massive image-text pairs and then fine-tuning on task-specific data, VLM in the remote…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Xingxing Weng , Chao Pang , Gui-Song Xia

Existing Medical Large Vision-Language Models (Med-LVLMs), encapsulating extensive medical knowledge, demonstrate excellent capabilities in understanding medical images. However, there remain challenges in visual localization in medical…

Computation and Language · Computer Science 2025-06-03 Yucheng Zhou , Lingran Song , Jianbing Shen

Instruction tuned Large Vision Language Models (LVLMs) have significantly advanced in generalizing across a diverse set of multi-modal tasks, especially for Visual Question Answering (VQA). However, generating detailed responses that are…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Anisha Gunjal , Jihan Yin , Erhan Bas

Writing radiology reports from medical images requires a high level of domain expertise. It is time-consuming even for trained radiologists and can be error-prone for inexperienced radiologists. It would be appealing to automate this task…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yuzhe Lu , Sungmin Hong , Yash Shah , Panpan Xu

Large Vision-Language Models offer a new paradigm for AI-driven image understanding, enabling models to perform tasks without task-specific training. This flexibility holds particular promise across medicine, where expert-annotated data is…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Anita Rau , Mark Endo , Josiah Aklilu , Jaewoo Heo , Khaled Saab , Alberto Paderno , Jeffrey Jopling , F. Christopher Holsinger , Serena Yeung-Levy

Accurate disease interpretation from radiology remains challenging due to imaging heterogeneity. Achieving expert-level diagnostic decisions requires integration of subtle image features with clinical knowledge. Yet major vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Difei Gu , Yunhe Gao , Mu Zhou , Dimitris Metaxas

Vision Language Models (VLMs) achieved rapid progress in the recent years. However, despite their growth, VLMs development is heavily grounded on English, leading to two main limitations: (i) the lack of multilingual and multimodal datasets…

Computation and Language · Computer Science 2026-04-21 Daniela Baiamonte , Elena Fano , Matteo Gabburo , Stefano Simonazzi , Leonardo Rigutini , Andrea Zugarini

Achieving deep alignment between vision and language remains a central challenge for Multimodal Large Language Models (MLLMs). These models often fail to fully leverage visual input, defaulting to strong language priors. Our approach first…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Aarti Ghatkesar , Ganesh Venkatesh

The development of Large Vision-Language Models (LVLMs) is striving to catch up with the success of Large Language Models (LLMs), yet it faces more challenges to be resolved. Very recent works enable LVLMs to localize object-level visual…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Zhipeng Huang , Zhizheng Zhang , Zheng-Jun Zha , Yan Lu , Baining Guo

The rapid development of large language models (LLMs) has spurred extensive research into their domain-specific capabilities, particularly mathematical reasoning. However, most open-source LLMs focus solely on mathematical reasoning,…

Computation and Language · Computer Science 2024-09-04 Shuai Peng , Di Fu , Liangcai Gao , Xiuqin Zhong , Hongguang Fu , Zhi Tang