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Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in…

Numerical Analysis · Mathematics 2016-12-21 Simon Arridge , Paul Beard , Marta Betcke , Ben Cox , Nam Huynh , Felix Lucka , Olumide Ogunlade , Edward Zhang

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. If the object…

Medical Physics · Physics 2017-09-08 Joemini Poudel , Thomas P. Matthews , Lei Li , Mark A. Anastasio , Lihong V. Wang

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

Photoacoustic computed tomography (PACT) is emerging as a new technique for functional brain imaging, primarily due to its capabilities in label-free hemodynamic imaging. Despite its potential, the transcranial application of PACT has…

Multispectral photoacoustic tomography (PAT) is an imaging modality that utilizes the photoacoustic effect to achieve non-invasive and high-contrast imaging of internal tissues. However, the hardware cost and computational demand of a…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yutian Zhong , Xiaoming Zhang , Zongxin Mo , Shuangyang Zhang , Wufan Chen , Li Qi

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…

Medical Physics · Physics 2016-11-15 Qiwei Sheng , Kun Wang , Thomas P. Matthews , Jun Xia , Liren Zhu , Lihong V. Wang , Mark A. Anastasio

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging modality that has great potential for a wide range of biomedical imaging applications. In this Note, we derive a hybrid reconstruction…

Analysis of PDEs · Mathematics 2015-06-11 Kun Wang , Mark A. Anastasio

Photoacoustic computed tomography (PACT) is a promising imaging modality that combines the advantages of optical contrast with ultrasound detection. Utilizing ultrasound transducers with larger surface areas can improve detection…

Photoacoustic (PA) computed tomography (PACT) shows great potentials in various preclinical and clinical applications. A great number of measurements are the premise that obtains a high-quality image, which implies a low imaging rate or a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Hengrong Lan , Juze Zhang , Changchun Yang , Fei Gao

A crucial limitation of current high-resolution 3D photoacoustic tomography (PAT) devices that employ sequential scanning is their long acquisition time. In previous work, we demonstrated how to use compressed sensing techniques to improve…

Numerical Analysis · Mathematics 2020-09-07 Felix Lucka , Nam Huynh , Marta Betcke , Edward Zhang , Paul Beard , Ben Cox , Simon Arridge

Photoacoustic Computed Tomography (PACT) is a major configuration of photoacoustic imaging, a hybrid noninvasive modality for both functional and molecular imaging. PACT has rapidly gained importance in the field of biomedical imaging due…

To obtain the initial pressure from the collected data on a planar sensor arrangement in Photoacoustic tomography, there exists an exact analytic frequency domain reconstruction formula. An efficient realization of this formula needs to…

Numerical Analysis · Mathematics 2015-01-14 Julian Schmid , Thomas Glatz , Behrooz Zabihian , Mengyang Liu , Wolfgang Drexler , Otmar Scherzer

Photoacoustic computed tomography (PACT) is a hybrid imaging modality, which combines the high optical contrast of pure optical imaging and the high penetration depth of ultrasound imaging. However, photoacoustic image dataset with good…

Medical Physics · Physics 2022-05-24 Tengbo Lyu , Changchun Yang , Jiadong Zhang , Shanshan Guo , Feng Gao , Fei Gao

Transcranial photoacoustic computed tomography (PACT) is an emerging neuroimaging modality, but skull-induced aberrations can result in severe image artifacts if not compensated for during image reconstruction. The development of advanced…

Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…

As an emerging medical diagnostic technology, photoacoustic imaging has been implemented for both preclinical and clinical applications. For clinical convenience, a handheld free scan photoacoustic tomography (PAT) system providing 3D…

Medical Physics · Physics 2022-03-18 Daohuai Jiang , Hongbo Chen , Yuting Shen , Yifan Zhang , Feng Gao , Rui Zheng , Fei Gao

Photoacoustic computed tomography (PACT) is a non-invasive imaging modality, similar to ultrasound, with wide-ranging medical applications. Conventional PACT images are degraded by wavefront distortion caused by the heterogeneous speed of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Tianao Li , Manxiu Cui , Cheng Ma , Emma Alexander

Photo-acoustic tomography (PAT) aims to leverage the photo-acoustic coupling between optical absorption of light sources and ultrasound (US) emission to obtain high contrast reconstructions of optical parameters with the high resolution of…

Analysis of PDEs · Mathematics 2016-09-21 Guillaume Bal , Amir Moradifam

In certain three-dimensional (3D) applications of photoacoustic computed tomography (PACT), including \textit{in vivo} breast imaging, hemispherical measurement apertures that enclose the object within their convex hull are employed for…

In photoacoustic computed tomography (PACT) with short-pulsed laser excitation, wideband acoustic signals are generated in biological tissues with frequencies related to the effective shapes and sizes of the optically absorbing targets.…

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