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To obtain the initial pressure from the collected data on a planar sensor arrangement in photoacoustic tomography, there exists an exact analytic frequency domain reconstruction formula. An efficient realization of this formula needs to…

Highly multiplexed microscopy enables rich spatial characterization of tissues at single-cell resolution, yet most analyses rely on two-dimensional sections despite inherently three-dimensional tissue organization. Acquiring dense…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Ido Harlev , Tamar Oukhanov , Raz Ben-Uri , Leeat Keren , Shai Bagon

Photoacoustic computed tomography (PACT) detects light-induced ultrasound waves to reconstruct the optical absorption contrast of the biological tissues. Due to its relatively deep penetration (several centimeters in soft tissue), high…

Medical Physics · Physics 2020-07-17 Yuqi Tang , Junjie Yao

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Photoacoustic imaging can achieve high-resolution three-dimensional visualization of optical absorbers at penetration depths ~ 1 cm in biological tissues by detecting optically-induced high ultrasound frequencies. Tomographic acquisition…

Optics · Physics 2015-05-15 Jérôme Gateau , Marc Gesnik , Jean-Marie Chassot , Emmanuel Bossy

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

Photoacoustic tomography (PAT) combines the advantages of the spectroscopic optical absorption contrast and acoustic resolution with deep penetration, and becomes an important novel biomedical imaging technology for scientific research and…

Instrumentation and Detectors · Physics 2021-12-23 Daohuai Jiang , Yifei Xu , Hengrong Lan , Feng Gao , Fei Gao

Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements…

Image and Video Processing · Electrical Eng. & Systems 2021-05-10 Hengrong Lan , Daohuai Jiang , Feng Gao , Fei Gao

In ultrasound nondestructive testing, a widespread approach is to take synthetic aperture measurements from the surface of a specimen to detect and locate defects within it. Based on these measurements, imaging is usually performed using…

Signal Processing · Electrical Eng. & Systems 2020-12-09 Jan Kirchhof , Sebastian Semper , Christoph W. Wagner , Eduardo Pérez , Florian Römer , Giovanni Del Galdo

Active incoherent millimeter-wave (AIM) imaging is a recently developed technique that has been shown to generate fast millimeter-wave imaging using sparse apertures and Fourier domain sampling. In these systems, spatial frequency sampling…

Signal Processing · Electrical Eng. & Systems 2026-03-26 Jorge R. Colon-Berrios , Derek Luzano , Daniel Chen , Jeffrey A. Nanzer

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

Photoacoustic tomography (PAT) is an emerging imaging modality that aims at measuring the high-contrast optical properties of tissues by means of high-resolution ultrasonic measurements. The interaction between these two types of waves is…

Analysis of PDEs · Mathematics 2021-07-27 Giovanni S. Alberti , Paolo Campodonico , Matteo Santacesaria

Spherical harmonics are a favorable technique for 3D representation, employing a frequency-based approach through the spherical harmonic transform (SHT). Typically, SHT is performed using equiangular sampling grids. However, these grids are…

Graphics · Computer Science 2025-02-28 Zikuan Li , Anyi Huang , Wenru Jia , Qiaoyun Wu , Mingqiang Wei , Jun Wang

Increasing the imaging speed is a central aim in photoacoustic tomography. This issue is especially important in the case of sequential scanning approaches as applied for most existing optical detection schemes. In this work we address this…

Numerical Analysis · Mathematics 2016-11-23 Markus Haltmeier , Thomas Berer , Sunghwan Moon , Peter Burgholzer

Accurate image reconstruction is crucial for photoacoustic (PA) computed tomography (PACT). Recently, deep learning has been used to reconstruct the PA image with a supervised scheme, which requires high-quality images as ground truth…

Image and Video Processing · Electrical Eng. & Systems 2023-09-22 Hengrong Lan , Lijie Huang , Zhiqiang Li , Jing Lv , Jianwen Luo

Purpose: Quasi-random Sobol-based sampling schemes exhibit deterministic structural artifacts when aggressively undersampled, particularly at low encoding densities required for accelerated 2D SPI/CSI. To address these limitations, two…

Medical Physics · Physics 2026-04-22 Fabian Bschorr , Pia Gebhard , Tobias Speidel , Volker Rasche

High-quality imaging in photoacoustic computed tomography (PACT) usually requires a high-channel count system for dense spatial sampling around the object to avoid aliasing-related artefacts. To reduce system complexity, various image…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Bowei Yao , Shilong Cui , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Jingyi Yu , Yuyao Zhang , Xiran Cai

Photoacoustic microscopy (PAM) is a novel implementation of photoacoustic imaging (PAI) for visualizing the 3D bio-structure, which is realized by raster scanning of the tissue. However, as three involved critical imaging parameters,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhengyuan Zhang , Haoran Jin , Zesheng Zheng , Wenwen Zhang , Wenhao Lu , Feng Qin , Arunima Sharma , Manojit Pramanik , Yuanjin Zheng