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Previous research has shown that humans are more receptive towards language models that that exhibit empathetic behavior. While empathy is essential for developing helpful dialogue agents, very few large corpora containing empathetic…
The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic…
As large language models (LLMs) are increasingly deployed as interactive agents, open-ended human-AI interactions can involve deceptive behaviors with serious real-world consequences, yet existing evaluations remain largely…
Large Language Model (LLM) personas with explicit specifications of attributes, background, and behavioural tendencies are increasingly used to simulate human conversations for tasks such as user modeling, social reasoning, and behavioural…
The deployment of Large Language Models (LLMs) in interactive systems necessitates a deep alignment with the nuanced and dynamic preferences of individual users. Current alignment techniques predominantly address universal human values or…
Foundation models (FMs) are driving a prominent shift in biomedical imaging from task-specific models to unified backbone models for diverse tasks. This opens an avenue to integrate imaging, pathology, clinical records, and genomics data…
In order to build self-consistent personalized dialogue agents, previous research has mostly focused on textual persona that delivers personal facts or personalities. However, to fully describe the multi-faceted nature of persona, image…
Mental health assessment is crucial for early intervention and effective treatment, yet traditional clinician-based approaches are limited by the shortage of qualified professionals. Recent advances in artificial intelligence have sparked…
Current works in the generation of personalized dialogue primarily contribute to the agent presenting a consistent personality and driving a more informative response. However, we found that the generated responses from most previous models…
For software interacting directly with real-world end-users, it is common practice to script scenario tests validating the system's compliance with a number of its features. However, these do not accommodate the replication of the type of…
Advancements in foundation models have catalyzed research in Embodied AI to develop interactive agents capable of environmental reasoning and interaction. Developing such agents requires diverse, large-scale datasets. Prior frameworks…
Despite the growing development of long-context large language models (LLMs), data-centric approaches relying on synthetic data have been hindered by issues related to faithfulness, which limit their effectiveness in enhancing model…
Patient-controlled data-sharing systems are increasingly promoted as a way to empower patients with greater autonomy over their health data. Yet it remains unclear how different stakeholders, especially patients and health system leaders,…
The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…
Counterfactual simulation - exploring hypothetical consequences under alternative clinical scenarios - holds promise for transformative applications such as personalized medicine and in silico trials. However, it remains challenging due to…
Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…
Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…
Psychiatric comorbidity is clinically significant yet challenging due to the complexity of multiple co-occurring disorders. To address this, we develop a novel approach integrating synthetic patient electronic medical record (EMR)…
User simulation is increasingly vital to develop and evaluate recommender systems (RSs). While Large Language Models (LLMs) offer promising avenues to simulate user behavior, they often struggle with the absence of specific task alignment…
Large language models (LLMs) are increasingly used as simulated participants in social science experiments, but their behavior is often unstable and highly sensitive to design choices. Prior evaluations frequently conflate base-model…