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Linear mixed models (LMMs) are instrumental for regression analysis with structured dependence, such as grouped, clustered, or multilevel data. However, selection among the covariates--while accounting for this structured…
Linear mixed models (LMM) are widely adopted in genome-wide association studies (GWAS) to account for population stratification and cryptic relatedness. However, the parameter estimation of LMMs imposes substantial computational burdens due…
Background: Understanding the relationship between the Omics and the phenotype is a central problem in precision medicine. The high dimensionality of metabolomics data challenges learning algorithms in terms of scalability and…
We develop a framework to study posterior contraction rates in sparse high dimensional generalized linear models (GLM). We introduce a new family of GLMs, denoted by clipped GLM, which subsumes many standard GLMs and makes minor…
The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from existing approaches are not necessarily…
Bayesian variable selection methods are powerful techniques for fitting and inferring on sparse high-dimensional linear regression models. However, many are computationally intensive or require restrictive prior distributions on model…
Feature selection is a crucial step in machine learning, especially for high-dimensional datasets, where irrelevant and redundant features can degrade model performance and increase computational costs. This paper proposes a novel…
Spatial generalized linear mixed models (SGLMMs) are popular and flexible models for non-Gaussian spatial data. They are useful for spatial interpolations as well as for fitting regression models that account for spatial dependence, and are…
With the improvement in the quantity and quality of remote sensing images, content-based remote sensing object retrieval (CBRSOR) has become an increasingly important topic. However, existing CBRSOR methods neglect the utilization of global…
Strategic classification~(SC) explores how individuals or entities modify their features strategically to achieve favorable classification outcomes. However, existing SC methods, which are largely based on linear models or shallow neural…
Large language models deliver strong generative performance but at the cost of massive parameter counts, memory use, and decoding latency. Prior work has shown that pruning and structured sparsity can preserve accuracy under substantial…
Generalized additive models for location, scale and shape (GAMLSS) are a flexible class of regression models that allow to model multiple parameters of a distribution function, such as the mean and the standard deviation, simultaneously.…
Higher-order Markov chains are frequently used to model categorical time series. However, a major problem with fitting such models is the exponentially growing number of parameters in the model order. A popular approach to parsimonious…
The recovery of a low rank matrix from a subset of noisy low-precision quantized samples arises in several applications such as collaborative filtering, intelligent recommendation and millimeter wave channel estimation with few bit ADCs. In…
Uncovering genuine relationships between a response variable of interest and a large collection of covariates is a fundamental and practically important problem. In the context of Gaussian linear models, both the Bayesian and non-Bayesian…
Various Large Language Models~(LLMs) from the Generative Pretrained Transformer(GPT) family have achieved outstanding performances in a wide range of text generation tasks. However, the enormous model sizes have hindered their practical use…
The Constrained Minimal Supersymmetric Standard Model (CMSSM) is one of the simplest and most widely-studied supersymmetric extensions to the standard model of particle physics. Nevertheless, current data do not sufficiently constrain the…
We propose Dirichlet Process mixtures of Generalized Linear Models (DP-GLM), a new method of nonparametric regression that accommodates continuous and categorical inputs, and responses that can be modeled by a generalized linear model. We…
Region-of-Interest (ROI)-based image compression allocates bits unevenly according to the semantic importance of different regions. Such differentiated coding typically induces a sharp-peaked and heavy-tailed distribution. This distribution…
Large Language Models(LLMs) excel in general tasks but struggle in specialized domains like healthcare due to limited domain-specific knowledge.Supervised Fine-Tuning(SFT) data construction for domain adaptation often relies on heuristic…