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With the growing prevalence of diabetes and the associated public health burden, it is crucial to identify modifiable factors that could improve patients' glycemic control. In this work, we seek to examine associations between medication…

Applications · Statistics 2025-12-22 Alexander Coulter , Rashmi N. Aurora , Naresh M. Punjabi , Irina Gaynanova

This paper deals with Gibbs samplers that include high dimensional conditional Gaussian distributions. It proposes an efficient algorithm that avoids the high dimensional Gaussian sampling and relies on a random excursion along a small set…

Computation · Statistics 2016-04-20 Olivier Féron , François Orieux , Jean-François Giovannelli

Lossy compression, widely used by scientists to reduce data from simulations, experiments, and observations, can distort features of interest even under bounded error. Such distortions may compromise downstream analyses and lead to…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-06 Yuxiao Li , Mingze Xia , Xin Liang , Bei Wang , Robert Underwood , Sheng Di , Hemant Sharma , Dishant Beniwal , Franck Cappello , Hanqi Guo

In practical domains, high-dimensional data are usually associated with diverse semantic labels, whereas traditional feature selection methods are designed for single-label data. Moreover, existing multi-label methods encounter two main…

Machine Learning · Computer Science 2025-05-26 Yan Zhong , Xingyu Wu , Xinping Zhao , Li Zhang , Xinyuan Song , Lei Shi , Bingbing Jiang

Analysis of high-dimensional data has led to increased interest in both single index models (SIMs) and the best-subset selection. SIMs provide an interpretable and flexible modeling framework for high-dimensional data, while the best-subset…

Machine Learning · Statistics 2025-08-19 Borui Tang , Jin Zhu , Junxian Zhu , Xueqin Wang , Heping Zhang

Sparse prediction with categorical data is challenging even for a moderate number of variables, because one parameter is roughly needed to encode one category or level. The Group Lasso is a well known efficient algorithm for selection…

Methodology · Statistics 2021-12-22 Szymon Nowakowski , Piotr Pokarowski , Wojciech Rejchel

Bayesian optimization (BO) is an effective technique for black-box optimization. However, its applicability is typically limited to moderate-budget problems due to the cubic complexity of fitting the Gaussian process (GP) surrogate model.…

Machine Learning · Statistics 2025-10-13 Qiyu Wei , Haowei Wang , Zirui Cao , Songhao Wang , Richard Allmendinger , Mauricio A Álvarez

Sparse Bayesian learning is a state-of-the-art supervised learning algorithm that can choose a subset of relevant samples from the input data and make reliable probabilistic predictions. However, in the presence of high-dimensional data…

Machine Learning · Computer Science 2020-01-10 Bingbing Jiang , Chang Li , Maarten de Rijke , Xin Yao , Huanhuan Chen

The validity of estimation and smoothing parameter selection for the wide class of generalized additive models for location, scale and shape (GAMLSS) relies on the correct specification of a likelihood function. Deviations from such…

Methodology · Statistics 2019-11-14 William H. Aeberhard , Eva Cantoni , Giampiero Marra , Rosalba Radice

In genomic studies, identifying biomarkers associated with a variable of interest is a major concern in biomedical research. Regularized approaches are classically used to perform variable selection in high-dimensional linear models.…

Methodology · Statistics 2020-07-22 Wencan Zhu , Céline Lévy-Leduc , Nils Ternès

We propose a new method for high-dimensional semi-supervised learning problems based on the careful aggregation of the results of a low-dimensional procedure applied to many axis-aligned random projections of the data. Our primary goal is…

Methodology · Statistics 2023-04-19 Tengyao Wang , Edgar Dobriban , Milana Gataric , Richard J. Samworth

In many applications, linear models fit the data poorly. This article studies an appealing alternative, the generalized regression model. This model only assumes that there exists an unknown monotonically increasing link function connecting…

Methodology · Statistics 2017-07-24 Fang Han , Hongkai Ji , Zhicheng Ji , Honglang Wang

Generalized linear models (GLMs) are routinely used for modeling relationships between a response variable and a set of covariates. The simple form of a GLM comes with easy interpretability, but also leads to concerns about model…

Methodology · Statistics 2023-11-10 Davide Agnoletto , Tommaso Rigon , David B. Dunson

It is common practice to use Laplace approximations to compute marginal likelihoods in Bayesian versions of generalised linear models (GLM). Marginal likelihoods combined with model priors are then used in different search algorithms to…

Methodology · Statistics 2022-02-01 Jon Lachmann , Geir Storvik , Florian Frommlet , Aliaksadr Hubin

We propose a nonparametric procedure to achieve fast inference in generative graphical models when the number of latent states is very large. The approach is based on iterative latent variable preselection, where we alternate between…

Machine Learning · Statistics 2021-10-06 Jacquelyn A. Shelton , Jan Gasthaus , Zhenwen Dai , Joerg Luecke , Arthur Gretton

Low-rank and sparse composite approximation is a natural idea to compress Large Language Models (LLMs). However, such an idea faces two primary challenges that adversely affect the performance of existing methods. The first challenge…

Machine Learning · Computer Science 2026-02-27 Changhai Zhou , Qian Qiao , Yuhua Zhou , Yuxin Wu , Shichao Weng , Weizhong Zhang , Cheng Jin

We introduce a generalized additive model for location, scale, and shape (GAMLSS) next of kin aiming at distribution-free and parsimonious regression modelling for arbitrary outcomes. We replace the strict parametric distribution…

Methodology · Statistics 2023-12-21 Sandra Siegfried , Lucas Kook , Torsten Hothorn

P-splines provide a flexible setting for modeling nonlinear model components based on a discretized penalty structure with a relatively simple computational backbone. Under a Bayesian inferential framework based on Markov chain Monte Carlo,…

Methodology · Statistics 2025-11-03 Oswaldo Gressani , Paul H. C. Eilers

Finite Gaussian mixture models are widely used for model-based clustering of continuous data. Nevertheless, since the number of model parameters scales quadratically with the number of variables, these models can be easily…

Methodology · Statistics 2018-09-25 Michael Fop , Thomas Brendan Murphy , Luca Scrucca

Feature selection has been widely used to alleviate compute requirements during training, elucidate model interpretability, and improve model generalizability. We propose SLM -- Sparse Learnable Masks -- a canonical approach for end-to-end…

Machine Learning · Computer Science 2023-04-07 Yihe Dong , Sercan O. Arik
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