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Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with…

Artificial Intelligence · Computer Science 2025-11-21 Deepthi Potluri , Aby Mammen Mathew , Jeffrey B DeWitt , Alexander L. Rasgon , Yide Hao , Junyuan Hong , Ying Ding

Biomedical question-answering (QA) systems require effective retrieval and generation components to ensure accuracy, efficiency, and scalability. This study systematically examines a Retrieval-Augmented Generation (RAG) system for…

Information Retrieval · Computer Science 2026-01-14 Linus Stuhlmann , Michael Alexander Saxer , Jonathan Fürst

Retrieval-Augmented Generation enhances language models by retrieving external knowledge to support informed and grounded responses. However, traditional RAG methods rely on fragment-level retrieval, limiting their ability to address…

Information Retrieval · Computer Science 2026-05-05 Wenbiao Tao , Xinyuan Li , Yunshi Lan , Weining Qian

We present a comprehensive framework for enhancing Retrieval-Augmented Generation (RAG) systems through dynamic retrieval strategies and reinforcement fine-tuning. This approach significantly improves large language models on…

Machine Learning · Computer Science 2025-05-21 Sakhinana Sagar Srinivas , Akash Das , Shivam Gupta , Venkataramana Runkana

Regulatory compliance in the pharmaceutical industry entails navigating through complex and voluminous guidelines, often requiring significant human resources. To address these challenges, our study introduces a chatbot model that utilizes…

Computation and Language · Computer Science 2024-02-07 Jaewoong Kim , Moohong Min

Visual retrieval-augmented generation (VRAG) augments vision-language models (VLMs) with external visual knowledge to ground reasoning and reduce hallucinations. Yet current VRAG systems often fail to reliably perceive and integrate…

Computation and Language · Computer Science 2025-10-14 Yubo Sun , Chunyi Peng , Yukun Yan , Shi Yu , Zhenghao Liu , Chi Chen , Zhiyuan Liu , Maosong Sun

Retrieval-Augmented Generation (RAG) has become a core paradigm for enhancing factual grounding and multi-hop reasoning in Large Language Models (LLMs). Traditional text-based RAG often retrieves logically irrelevant pseudo-evidence, while…

Artificial Intelligence · Computer Science 2026-05-08 Jiarui Zhong , Hong Cai Chen

We present HiRMed (Hierarchical RAG-enhanced Medical Test Recommendation), a novel tree-structured recommendation system that leverages Retrieval-Augmented Generation (RAG) for intelligent medical test recommendations. Unlike traditional…

Information Retrieval · Computer Science 2025-01-07 Yahe Yang , Chengyue Huang

Retrieval-Augmented Generation (RAG) has demonstrated considerable effectiveness in open-domain question answering. However, when applied to heterogeneous documents, comprising both textual and tabular components, existing RAG approaches…

Computation and Language · Computer Science 2025-10-01 Xiaohan Yu , Pu Jian , Chong Chen

Identifying the appropriate regulatory standard applicability remains a critical yet understudied challenge in medical device compliance, frequently necessitating expert interpretation of fragmented and heterogeneous documentation across…

Artificial Intelligence · Computer Science 2025-06-24 Yu Han , Aaron Ceross , Jeroen H. M. Bergmann

Large language models (LLMs) inevitably exhibit hallucinations since the accuracy of generated texts cannot be secured solely by the parametric knowledge they encapsulate. Although retrieval-augmented generation (RAG) is a practicable…

Computation and Language · Computer Science 2024-10-08 Shi-Qi Yan , Jia-Chen Gu , Yun Zhu , Zhen-Hua Ling

This paper introduces an approach for training o1-like RAG models that retrieve and reason over relevant information step by step before generating the final answer. Conventional RAG methods usually perform a single retrieval step before…

Information Retrieval · Computer Science 2025-10-13 Liang Wang , Haonan Chen , Nan Yang , Xiaolong Huang , Zhicheng Dou , Furu Wei

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

Automated question-answering (QA) systems increasingly rely on retrieval-augmented generation (RAG) to ground large language models (LLMs) in authoritative medical knowledge, ensuring clinical accuracy and patient safety in Artificial…

Computation and Language · Computer Science 2026-03-05 Aswini Sivakumar , Vijayan Sugumaran , Yao Qiang

Chronic osteomyelitis presents substantial prognostic challenges due to its high recurrence risk and complex postoperative recovery trajectories. Traditional assessment often relies on manual scoring systems, which limit scalability,…

Information Retrieval · Computer Science 2026-05-25 Daqian Shi , Pei Han , Jishizhan Chen , Yang Wang , Xiaolei Diao , Xianyou Zheng , Pengfei Cheng

Retrieval-augmented generation (RAG) enhances the text generation capabilities of large language models (LLMs) by integrating external knowledge and up-to-date information. However, traditional RAG systems are limited by static workflows…

Diabetic Retinopathy (DR) is a leading cause of preventable blindness among working-age adults worldwide, yet most automated screening systems are limited to image-level classification and lack clinically structured reporting. We propose…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Abdelrahman Zaian , Sheethal Bhat , Mohamed Abdalkader , Andreas Maier

Retrieval-Augmented Generation (RAG) integrates non-parametric knowledge into Large Language Models (LLMs), typically from unstructured texts and structured graphs. While recent progress has advanced text-based RAG to multi-turn reasoning…

Computation and Language · Computer Science 2025-12-11 Yucan Guo , Miao Su , Saiping Guan , Zihao Sun , Xiaolong Jin , Jiafeng Guo , Xueqi Cheng
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