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This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Retrieval-augmented generation combined with reinforcement learning has shown promise for grounding large language models in trustworthy medical evidence. However, existing methods rely on exact-match binary rewards, which in clinical…

Artificial Intelligence · Computer Science 2026-05-28 Yuwei Miao , Gen Li , Yunsheng Zeng , Xiandong Li , Yujin Wang , Siyu Chen , Luning Wang , Yunhao Qiao , Junfeng Wang , Jianwei Lv , Bo Yuan

Vision-language retrieval-augmented generation (RAG) has become an effective approach for tackling Knowledge-Based Visual Question Answering (KB-VQA), which requires external knowledge beyond the visual content presented in images. The…

Information Retrieval · Computer Science 2025-09-15 Wei Yang , Jingjing Fu , Rui Wang , Jinyu Wang , Lei Song , Jiang Bian

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Retrieval-augmented generation (RAG) improves large language model reliability by grounding generated responses in external evidence. However, RAG performance depends on the relevance of retrieved passages, the quality of evidence ranking,…

Information Retrieval · Computer Science 2026-05-05 Fariba Afrin Irany , Sampson Akwafuo

Retrieval-augmented generation (RAG) has been widely adopted to ground large language models (LLMs) in external knowledge, yet it remains largely underexplored for improving reasoning. Existing methods either rely on online exploration…

Artificial Intelligence · Computer Science 2026-02-10 Jiaxiang Chen , Zhuo Wang , Mingxi Zou , Qifan Wang , Zenglin Xu

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Medical retrieval-augmented generation (RAG) systems typically operate on text chunks extracted from biomedical literature, discarding the rich visual content (tables, figures, structured layouts) of original document pages. We propose…

Artificial Intelligence · Computer Science 2026-05-01 Xupeng Chen , Binbin Shi , Chenqian Le , Jiaqi Zhang , Kewen Wang , Ran Gong , Jinhan Zhang , Chihang Wang

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Large Vision-Language Models (LVLMs) have made remarkable strides in multimodal tasks such as visual question answering, visual grounding, and complex reasoning. However, they remain limited by static training data, susceptibility to…

Artificial Intelligence · Computer Science 2025-08-27 Chan-Wei Hu , Yueqi Wang , Shuo Xing , Chia-Ju Chen , Suofei Feng , Ryan Rossi , Zhengzhong Tu

As AI chatbots gain adoption in clinical medicine, developing effective frameworks for complex, emerging diseases presents significant challenges. We developed and evaluated six Retrieval-Augmented Generation (RAG) corpus configurations for…

Artificial Intelligence · Computer Science 2025-10-20 Philip DiGiacomo , Haoyang Wang , Jinrui Fang , Yan Leng , W Michael Brode , Ying Ding

Retrieval-augmented generation (RAG) is a well-suited technique for retrieving privacy-sensitive Electronic Health Records (EHR). It can serve as a key module of the healthcare copilot, helping reduce misdiagnosis for healthcare…

Computation and Language · Computer Science 2025-06-30 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

Automated radiology report generation has gained increasing attention with the rise of deep learning and large language models. However, fully generative approaches often suffer from hallucinations and lack clinical grounding, limiting…

Quantitative Methods · Quantitative Biology 2026-05-01 Himadri S Samanta

Retrieval-Augmented Generation (RAG) aims to reduce hallucination by grounding answers in retrieved evidence, yet hallucinated answers remain common even when relevant documents are available. Existing evaluations focus on answer-level or…

Computation and Language · Computer Science 2026-05-21 Passant Elchafei , Monorama Swain , Shahed Masoudian , Markus Schedl

Retrieval-Augmented Generation (RAG) has emerged as a powerful paradigm for enhancing the capabilities of large language models. However, existing RAG evaluation predominantly focuses on text retrieval and relies on opaque, end-to-end…

Information Retrieval · Computer Science 2025-05-19 Chuan Xu , Qiaosheng Chen , Yutong Feng , Gong Cheng

Retrieval-Augmented Generation (RAG) significantly improves the factuality of Large Language Models (LLMs), yet standard pipelines often lack mechanisms to verify inter- mediate reasoning, leaving them vulnerable to hallucinations in…

Computation and Language · Computer Science 2026-03-12 Eeham Khan , Luis Rodriguez , Marc Queudot

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…

Computation and Language · Computer Science 2025-10-21 Yingpeng Ning , Yuanyuan Sun , Ling Luo , Yanhua Wang , Yuchen Pan , Hongfei Lin

Document Visual Question Answering (Document VQA) must cope with documents that span dozens of pages, yet leading systems still concatenate every page or rely on very large vision-language models, both of which are memory-hungry.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Eric López , Artemis Llabrés , Ernest Valveny

Retrieval-Augmented Generation (RAG) improves generation quality by incorporating evidence retrieved from large external corpora. However, most existing methods rely on statically selecting top-k passages based on individual relevance,…

Artificial Intelligence · Computer Science 2026-01-09 Yi Jiang , Sendong Zhao , Jianbo Li , Bairui Hu , Yanrui Du , Haochun Wang , Bing Qin
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