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Conformal prediction provides a powerful framework for constructing distribution-free prediction regions with finite-sample coverage guarantees. While extensively studied in univariate settings, its extension to multi-output problems…

Machine Learning · Statistics 2025-02-04 Victor Dheur , Matteo Fontana , Yorick Estievenart , Naomi Desobry , Souhaib Ben Taieb

We introduce a comprehensive framework for modeling single cell transcriptomic responses to perturbations, aimed at standardizing benchmarking in this rapidly evolving field. Our approach includes a modular and user-friendly model…

This manuscript presents the following: (1) an improved version of the Binary Simultaneous Perturbation Stochastic Approximation (SPSA) Method for feature selection in machine learning (Aksakalli and Malekipirbazari, Pattern Recognition…

The rapid release of both language models and benchmarks makes it increasingly costly to evaluate every model on every dataset. In practice, models are often evaluated on different samples, making scores difficult to compare across studies.…

Computation and Language · Computer Science 2026-04-16 Eliya Habba , Itay Itzhak , Asaf Yehudai , Yotam Perlitz , Elron Bandel , Michal Shmueli-Scheuer , Leshem Choshen , Gabriel Stanovsky

Statistical methods for identifying harmful chemicals in a correlated mixture often assume linearity in exposure-response relationships. Non-monotonic relationships are increasingly recognised (e.g., for endocrine-disrupting chemicals);…

Applications · Statistics 2020-11-11 Nina Lazarevic , Luke D. Knibbs , Peter D. Sly , Adrian G. Barnett

In the era of increasingly complex AI models for time series forecasting, progress is often measured by marginal improvements on benchmark leaderboards. However, this approach suffers from a fundamental flaw: standard evaluation metrics…

Machine Learning · Computer Science 2026-05-28 Wanjin Feng , Yuan Yuan , Jingtao Ding , Yong Li

Computational biomarkers (CBs) are histopathology-derived patterns extracted from hematoxylin-eosin (H&E) whole-slide images (WSIs) using artificial intelligence (AI) to predict therapeutic response or prognosis. Recently, slide-level…

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…

Machine learning applications frequently come with multiple diverse objectives and constraints that can change over time. Accordingly, trained models can be tuned with sets of hyper-parameters that affect their predictive behavior (e.g.,…

Machine Learning · Computer Science 2022-10-17 Bracha Laufer-Goldshtein , Adam Fisch , Regina Barzilay , Tommi Jaakkola

Selection bias can hinder accurate estimation of association parameters in binary disease risk models using non-probability samples like electronic health records (EHRs). The issue is compounded when participants are recruited from multiple…

Using 286 research papers collected from Web of Science, ScienceDirect, SpringerLink, arXiv, and Google Scholar databases, a systematic review methodology was adopted to review and summarize the current challenges and potential future…

Information Retrieval · Computer Science 2024-07-30 Xin Ma , Mingyue Li , Xuguang Liu

There is a critical need for standard approaches to assess, report, and compare the technical performance of genome-scale differential gene expression experiments. We assess technical performance with a proposed "standard" dashboard of…

Most Performance-based Research Funding Systems (PRFS) draw on peer review and bibliometric indicators, two different methodologies which are sometimes combined. A common argument against the use of indicators in such research evaluation…

Digital Libraries · Computer Science 2018-05-23 David Pride , Petr Knoth

Fairness research in machine learning often centers on ensuring equitable performance of individual models. However, real-world recommendation systems are built on multiple models and even multiple stages, from candidate retrieval to…

Artificial Intelligence · Computer Science 2025-01-03 Brian Hsu , Cyrus DiCiccio , Natesh Sivasubramoniapillai , Hongseok Namkoong

Progress in hardware model checking depends critically on high-quality benchmarks. However, the community faces a significant benchmark gap: existing suites are limited in number, often distributed only in representations such as BTOR2…

Hardware Architecture · Computer Science 2026-02-27 Guangyu Hu , Xiaofeng Zhou , Wei Zhang , Hongce Zhang

Benchmarking is crucial for testing and validating any system, even more so in real-time systems. Typical real-time applications adhere to well-understood abstractions: they exhibit a periodic behavior, operate on a well-defined working…

Software Engineering · Computer Science 2022-08-02 Mattia Nicolella , Shahin Roozkhosh , Denis Hoornaert , Andrea Bastoni , Renato Mancuso

We propose a distributional framework for benchmarking socio-technical risks of foundation models with quantified statistical significance. Our approach hinges on a new statistical relative testing based on first and second order stochastic…

Environments with procedurally generated content serve as important benchmarks for testing systematic generalization in deep reinforcement learning. In this setting, each level is an algorithmically created environment instance with a…

Machine Learning · Computer Science 2021-06-15 Minqi Jiang , Edward Grefenstette , Tim Rocktäschel

Propensity scores are commonly used to reduce the confounding bias in non-randomized observational studies for estimating the average treatment effect. An important assumption underlying this approach is that all confounders that are…

Methodology · Statistics 2022-08-02 Youfei Yu , Jiacong Du , Min Zhang , Zhenke Wu , Andrew M. Ryan , Bhramar Mukherjee

In recent era prediction of enzyme class from an unknown protein is one of the challenging tasks in bioinformatics. Day to day the number of proteins is increases as result the prediction of enzyme class gives a new opportunity to…

Machine Learning · Computer Science 2019-01-21 Chhote Lal Prasad Gupta , Anand Bihari , Sudhakar Tripathi
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