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Skin cancer is a major concern to public health, accounting for one-third of the reported cancers. If not detected early, the cancer has the potential for severe consequences. Recognizing the critical need for effective skin cancer…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Niful Islam , Khan Md Hasib , Fahmida Akter Joti , Asif Karim , Sami Azam

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Background. RGB-trained capsule-endoscopy classifiers underperform on small-vessel vascular findings by conflating hemoglobin contrast with bile and illumination falloff. Thus, here we test whether a Monte Carlo-inspired analytic model can…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Chengshuai Yang , Lei Xing , Gregory Entin , Roopa Vemulapalli , Lisa Casey , Raiyan Tripti Zaman

A mutation in the DNA of a single cell that compromises its function initiates leukemia,leading to the overproduction of immature white blood cells that encroach upon the space required for the generation of healthy blood cells.Leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Md. Abu Ahnaf Mollick , Md. Mahfujur Rahman , D. M. Asadujjaman , Abdullah Tamim , Nosin Anjum Dristi , Md. Takbir Hossen

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Circulating blood cell clusters (CCCs) containing red blood cells (RBCs), white blood cells(WBCs), and platelets are significant biomarkers linked to conditions like thrombosis, infection, and inflammation. Flow cytometry, paired with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Suqiang Ma , Subhadeep Sengupta , Yao Lee , Beikang Gu , Xianyan Chen , Xianqiao Wang , Yang Liu , Mengjia Xu , Galit H. Frydman , He Li

Human blood primarily comprises plasma, red blood cells, white blood cells, and platelets. It plays a vital role in transporting nutrients to different organs, where it stores essential health-related data about the human body. Blood cells…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Rabia Asghar , Sanjay Kumar , Paul Hynds , Abeera Mahfooz

The aim of this work is to propose an ensemble of descriptors for Melanoma Classification, whose performance has been evaluated on validation and test datasets of the melanoma challenge 2018. The system proposed here achieves a strong…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Loris Nanni , Alessandra Lumini , Stefano Ghidoni

Language models are strong few-shot learners and achieve good overall accuracy in text classification tasks, masking the fact that their results suffer from great class accuracy imbalance. We believe that the pursuit of overall accuracy…

Computation and Language · Computer Science 2025-07-28 Ruixi Lin , Ziqiao Wang , Yang You

Many real-world applications reveal difficulties in learning classifiers from imbalanced data. The rising big data era has been witnessing more classification tasks with large-scale but extremely imbalance and low-quality datasets. Most of…

Machine Learning · Computer Science 2020-10-20 Zhining Liu , Wei Cao , Zhifeng Gao , Jiang Bian , Hechang Chen , Yi Chang , Tie-Yan Liu

Accurate classification of blood cells plays a key role in improving automated blood analysis for both medical and veterinary applications. This work presents a two-stage deep clustering method for classifying blood cells from…

Quantitative Methods · Quantitative Biology 2025-09-25 Mihaela Macarie-Ancau , Adrian Groza

Recognizing the types of white blood cells (WBCs) in microscopic images of human blood smears is a fundamental task in the fields of pathology and hematology. Although previous studies have made significant contributions to the development…

Image and Video Processing · Electrical Eng. & Systems 2023-05-22 Satoshi Tsutsui , Zhengyang Su , Bihan Wen

We present a foundation modeling framework that leverages deep learning to uncover latent genetic signatures across the hematopoietic hierarchy. Our approach trains a fully connected autoencoder on multipotent progenitor cells, reducing…

Machine Learning · Computer Science 2025-03-27 Gabriel Bo , Justin Gu , Christopher Sun

The objective of the study is to evaluate the efficiency of a multi layer neural network models built by combining Recurrent Neural Network(RNN) and Convolutional Neural Network(CNN) for solving the problem of classifying different types of…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Indraneel Ghosh , Siddhant Kundu

Ensemble technique and under-sampling technique are both effective tools used for imbalanced dataset classification problems. In this paper, a novel ensemble method combining the advantages of both ensemble learning for biasing classifiers…

Machine Learning · Computer Science 2025-02-05 Jinyan Li , Yaoyang Wu , Simon Fong , Antonio J. Tallón-Ballesteros , Xin-she Yang , Sabah Mohammed , Feng Wu

Computer-aided methods for analyzing white blood cells (WBC) have become widely popular due to the complexity of the manual process. Recent works have shown highly accurate segmentation and detection of white blood cells from microscopic…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Changhun Jung , Mohammed Abuhamad , Jumabek Alikhanov , Aziz Mohaisen , Kyungja Han , DaeHun Nyang

Mass cytometry technology enables the simultaneous measurement of over 40 proteins on single cells. This has helped immunologists to increase their understanding of heterogeneity, complexity, and lineage relationships of white blood cells.…

One of the most significant current discussions in the field of data mining is classifying imbalanced data. In recent years, several ways are proposed such as algorithm level (internal) approaches, data level (external) techniques, and…

Machine Learning · Computer Science 2021-06-03 Maliheh Roknizadeh , Hossein Monshizadeh Naeen

Highly imbalanced datasets are ubiquitous in medical image classification problems. In such problems, it is often the case that rare classes associated to less prevalent diseases are severely under-represented in labeled databases,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Adrian Galdran , Gustavo Carneiro , Miguel A. González Ballester

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Daiki Nishiyama , Hiroaki Miyoshi , Noriaki Hashimoto , Koichi Ohshima , Hidekata Hontani , Ichiro Takeuchi , Jun Sakuma