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The hemocompatibility of blood-contacting medical devices remains one of the major challenges in biomedical engineering and makes research in the field of new and improved materials inevitable. However, current in-vitro test and analysis…

Quantitative Methods · Quantitative Biology 2020-10-14 Johanna C. Clauser , Judith Maas , Jutta Arens , Thomas Schmitz-Rode , Ulrich Steinseifer , Benjamin Berkels

The complementary information found in different modalities of patient data can aid in more accurate modelling of a patient's disease state and a better understanding of the underlying biological processes of a disease. However, the…

Machine Learning · Computer Science 2025-04-18 Annette Spooner , Mohammad Karimi Moridani , Azadeh Safarchi , Salim Maher , Fatemeh Vafaee , Amany Zekry , Arcot Sowmya

Gastrointestinal (GI) bleeding is a serious medical condition that presents significant diagnostic challenges, particularly in settings with limited access to healthcare resources. Wireless Capsule Endoscopy (WCE) has emerged as a powerful…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 S. Balasubramanian , Ammu Abhishek , Yedu Krishna , Darshan Gera

We design an efficient algorithm that outputs tests for identifying predominantly homogeneous subcohorts of patients from large in-homogeneous datasets. Our theoretical contribution is a rounding technique, similar to that of Goemans and…

Quantitative Methods · Quantitative Biology 2025-11-25 Pratik Worah

Learning on small data is a challenge frequently encountered in many real-world applications. In this work we study how effective quantum ensemble models are when trained on small data problems in healthcare and life sciences. We…

Machine learning (ML) technologies are known to be riddled with ethical and operational problems, however, we are witnessing an increasing thrust by businesses to deploy them in sensitive applications. One major issue among many is that ML…

Machine Learning · Computer Science 2023-11-01 Preetam Prabhu Srikar Dammu , Yunhe Feng , Chirag Shah

Biomedical data are widely accepted in developing prediction models for identifying a specific tumor, drug discovery and classification of human cancers. However, previous studies usually focused on different classifiers, and overlook the…

Quantitative Methods · Quantitative Biology 2019-11-05 Shigang Liu , Jun Zhang , Yang Xiang , Wanlei Zhou , Dongxi Xiang

We consider the problem of image classification for the purpose of aiding doctors in dermatological diagnosis. Dermatological diagnosis poses two major challenges for standard off-the-shelf techniques: First, the data distribution is…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Viraj Prabhu , Anitha Kannan , Murali Ravuri , Manish Chablani , David Sontag , Xavier Amatriain

Gastric cancer is the fifth most common cancer in the world. At the same time, it is also the fourth most deadly cancer. Early detection of cancer exists as a guide for the treatment of gastric cancer. Nowadays, computer technology has…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Weiming Hu , Haoyuan Chen , Wanli Liu , Xiaoyan Li , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek , Chen Li

Woody Breast (WB) and Spaghetti Meat (SM) myopathies significantly impact poultry meat quality, yet current detection methods rely either on subjective manual evaluation or costly laboratory-grade imaging systems. We address the problem of…

Machine Learning · Computer Science 2026-04-16 Chaitanya Pallerla , Siavash Mahmoudi , Dongyi Wang

Imbalanced datasets in medical imaging are characterized by skewed class proportions and scarcity of abnormal cases. When trained using such data, models tend to assign higher probabilities to normal cases, leading to biased performance.…

Machine Learning · Computer Science 2023-11-14 Yumnah Hasan , Fatemeh Amerehi , Patrick Healy , Conor Ryan

To address the challenges of imbalanced multi-class datasets typically used for rare event detection in critical cyber-physical systems, we propose an optimal, efficient, and adaptable mixed integer programming (MIP) ensemble weighting…

Machine Learning · Computer Science 2025-04-16 Georgios Tertytchny , Georgios L. Stavrinides , Maria K. Michael

The dynamic ensemble selection of classifiers is an effective approach for processing label-imbalanced data classifications. However, such a technique is prone to overfitting, owing to the lack of regularization methods and the dependence…

Machine Learning · Computer Science 2020-11-09 Chen Wang , Chengyuan Deng , Zhoulu Yu , Dafeng Hui , Xiaofeng Gong , Ruisen Luo

Diagnosing hematological malignancies requires identification and classification of white blood cells in peripheral blood smears. Domain shifts caused by different lab procedures, staining, illumination, and microscope settings hamper the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Raheleh Salehi , Ario Sadafi , Armin Gruber , Peter Lienemann , Nassir Navab , Shadi Albarqouni , Carsten Marr

Sickle cell anemia, which is characterized by abnormal erythrocyte morphology, can be detected using microscopic images. Computational techniques in medicine enhance the diagnosis and treatment efficiency. However, many computational…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Victor Júnio Alcântara Cardoso , Rodrigo Moreira , João Fernando Mari , Larissa Ferreira Rodrigues Moreira

Imbalanced class distribution is a common problem in a number of fields including medical diagnostics, fraud detection, and others. It causes bias in classification algorithms leading to poor performance on the minority class data. In this…

Machine Learning · Computer Science 2020-09-23 Firuz Kamalov , Dmitry Denisov

Image classification technology and performance based on Deep Learning have already achieved high standards. Nevertheless, many efforts have conducted to improve the stability of classification via ensembling. However, the existing ensemble…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 YeongHyeon Park , JoonSung Lee , Wonseok Park

The huge amount of data acquired by high-throughput sequencing requires data reduction for effective analysis. Here we give a clustering algorithm for genome-wide open chromatin data using a new data reduction method. This method regards…

Genomics · Quantitative Biology 2024-10-14 Azusa Tanaka , Yasuhiro Ishitsuka , Hiroki Ohta , Akihiro Fujimoto , Jun-ichirou Yasunaga , Masao Matsuoka

In many real-world pattern recognition scenarios, such as in medical applications, the corresponding classification tasks can be of an imbalanced nature. In the current study, we focus on binary, imbalanced classification tasks, i.e.~binary…

Machine Learning · Computer Science 2020-12-01 Peter Bellmann , Heinke Hihn , Daniel A. Braun , Friedhelm Schwenker

Background: Understanding the relationship between the Omics and the phenotype is a central problem in precision medicine. The high dimensionality of metabolomics data challenges learning algorithms in terms of scalability and…

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