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Graph representation learning in Euclidean space, despite its widespread adoption and proven utility in many domains, often struggles to effectively capture the inherent hierarchical and complex relational structures prevalent in real-world…
A comprehensive three-dimensional (3D) map of tissue architecture and gene expression is crucial for illuminating the complexity and heterogeneity of tissues across diverse biomedical applications. However, most spatial transcriptomics (ST)…
We introduce 3DShape2VecSet, a novel shape representation for neural fields designed for generative diffusion models. Our shape representation can encode 3D shapes given as surface models or point clouds, and represents them as neural…
This paper provides theoretical and computational developments in statistical shape analysis of shape graphs, and demonstrates them using analysis of complex data from retinal blood-vessel (RBV) networks. The shape graphs are represented by…
Motivated by the computational and storage challenges that dense embeddings pose, we introduce the problem of latent network summarization that aims to learn a compact, latent representation of the graph structure with dimensionality that…
The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…
The human brain displays a complex network topology, whose structural organization is widely studied using diffusion tensor imaging. The original geometry from which emerges the network topology is known, as well as the localization of the…
When created faithfully from real-world data, Digital 3D representations of objects can be useful for human or computer-assisted analysis. Such models can also serve for generating training data for machine learning approaches in settings…
Deep neural networks can be powerful tools, but require careful application-specific design to ensure that the most informative relationships in the data are learnable. In this paper, we apply deep neural networks to the nonlinear…
Neurons exhibit intricate geometries within their neurite networks, which play a crucial role in processes such as signaling and nutrient transport. Accurate simulation of material transport in the networks is essential for understanding…
Computational fluid dynamics (CFD) simulation provides valuable information on blood flow from the vascular geometry. However, it requires extracting precise models of arteries from low-resolution medical images, which remains challenging.…
We present DeepVesselNet, an architecture tailored to the challenges faced when extracting vessel networks or trees and corresponding features in 3-D angiographic volumes using deep learning. We discuss the problems of low execution speed…
Segmentation of lung tissue in computed tomography (CT) images is a precursor to most pulmonary image analysis applications. Semantic segmentation methods using deep learning have exhibited top-tier performance in recent years, however…
This paper introduces self-supervised neural network models to tackle several fundamental problems in the field of 3D human body analysis and processing. First, we propose VariShaPE (Varifold Shape Parameter Estimator), a novel architecture…
Representing and reasoning about 3D structures of macromolecules is emerging as a distinct challenge in machine learning. Here, we extend recent work on geometric vector perceptrons and apply equivariant graph neural networks to a wide…
Graph representation learning is a fundamental problem for modeling relational data and benefits a number of downstream applications. Traditional Bayesian-based graph models and recent deep learning based GNN either suffer from…
Graphs as a type of data structure have recently attracted significant attention. Representation learning of geometric graphs has achieved great success in many fields including molecular, social, and financial networks. It is natural to…
Image-based, patient-specific modelling of hemodynamics can improve diagnostic capabilities and provide complementary insights to better understand the hemodynamic treatment outcomes. However, computational fluid dynamics simulations remain…
Learning embeddings of entities and relations existing in knowledge bases allows the discovery of hidden patterns in data. In this work, we examine the geometrical space's contribution to the task of knowledge base completion. We focus on…
Graph-structured combinatorial challenges are inherently difficult due to their nonlinear and intricate nature, often rendering traditional computational methods ineffective or expensive. However, these challenges can be more naturally…