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FRET-based approaches are a unique tool for sensing the immediate surroundings and interactions of (bio)molecules. FRET imaging and FLIM (Fluorescence Lifetime Imaging Microscopy) enable the visualization of the spatial distribution of…

Typical attempts to improve the capability of visual place recognition techniques include the use of multi-sensor fusion and integration of information over time from image sequences. These approaches can improve performance but have…

Robotics · Computer Science 2019-03-11 Stephen Hausler , Adam Jacobson , Michael Milford

3D object detection is a core component of automated driving systems. State-of-the-art methods fuse RGB imagery and LiDAR point cloud data frame-by-frame for 3D bounding box regression. However, frame-by-frame 3D object detection suffers…

Computer Vision and Pattern Recognition · Computer Science 2021-05-24 Emeç Erçelik , Ekim Yurtsever , Alois Knoll

Imaging of rapidly occurring events in biology requires high temporal resolution. In this review article, I have tried to investigate an approximate estimate to quantify temporal resolution limit of a fluorescence imaging system. It was…

Medical Physics · Physics 2014-07-25 Partha Pratim Mondal

Fast neuromorphic event-based vision sensors (Dynamic Vision Sensor, DVS) can be combined with slower conventional frame-based sensors to enable higher-quality inter-frame interpolation than traditional methods relying on fixed motion…

Computer Vision and Pattern Recognition · Computer Science 2021-12-20 Adam Radomski , Andreas Georgiou , Thomas Debrunner , Chenghan Li , Luca Longinotti , Minwon Seo , Moosung Kwak , Chang-Woo Shin , Paul K. J. Park , Hyunsurk Eric Ryu , Kynan Eng

FRET measurements can provide dynamic spatial information on length scales smaller than the diffraction limit of light. Several methods exist to measure FRET between fluorophores, including Fluorescence Lifetime Imaging Microscopy (FLIM),…

Quantitative Methods · Quantitative Biology 2017-01-09 Bryan Kaye , Peter J. Foster , Tae Yeon Yoo , Daniel J. Needleman

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller

Unlike conventional frame-based sensors, event-based visual sensors output information through spikes at a high temporal resolution. By only encoding changes in pixel intensity, they showcase a low-power consuming, low-latency approach to…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Rohan Ghosh , Anupam Gupta , Siyi Tang , Alcimar Soares , Nitish Thakor

Strong turbulence conditions create amplitude aberrations through the effects of near-field diffraction. When integrated over long optical path lengths, amplitude aberrations (seen as scintillation) can nullify local areas in the recorded…

Instrumentation and Methods for Astrophysics · Physics 2020-12-30 Justin R. Crepp , Stanimir O. Letchev , Sam J. Potier , Joshua H. Follansbee , Nicholas T. Tusay

An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…

Optics · Physics 2009-11-11 C. Vinegoni , T. Ralston , W. Tan , W. Luo , D. L. Marks , S. A. Boppart

We present a rapid-scanning approach to fluorescence-detected two-dimensional electronic spectroscopy that combines acousto-optic phase-modulation with digital lock-in detection. The approach shifts the signal detection window to suppress…

Analog computing at the edge is an emerging strategy to limit data storage and transmission requirements, as well as energy consumption, and its practical implementation is in its initial stages of development. Translating properties of…

Signal Processing · Electrical Eng. & Systems 2025-12-09 Giuseppe Leo , Paolo Gibertini , Irem Ilter , Erika Covi , Ole Richter , Elisabetta Chicca

Event cameras are bio-inspired vision sensors that output pixel-level brightness changes instead of standard intensity frames. They offer significant advantages over standard cameras, namely a very high dynamic range, no motion blur, and a…

Robotics · Computer Science 2019-01-21 Elias Mueggler , Guillermo Gallego , Henri Rebecq , Davide Scaramuzza

Tracking any point based on image frames is constrained by frame rates, leading to instability in high-speed scenarios and limited generalization in real-world applications. To overcome these limitations, we propose an image-event fusion…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Jiaxiong Liu , Bo Wang , Zhen Tan , Jinpu Zhang , Hui Shen , Dewen Hu

Scalable atom-based quantum platforms for simulation, computing, and metrology require fast high-fidelity, low-loss imaging of individual atoms. Standard fluorescence detection methods rely on continuous cooling, limiting the detection…

Effective feature fusion of multispectral images plays a crucial role in multi-spectral object detection. Previous studies have demonstrated the effectiveness of feature fusion using convolutional neural networks, but these methods are…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Jifeng Shen , Yifei Chen , Yue Liu , Xin Zuo , Heng Fan , Wankou Yang

Current Event Stream Super-Resolution (ESR) methods overlook the redundant and complementary information present in positive and negative events within the event stream, employing a direct mixing approach for super-resolution, which may…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Quanmin Liang , Zhilin Huang , Xiawu Zheng , Feidiao Yang , Jun Peng , Kai Huang , Yonghong Tian

Structured illumination microscopy (SIM) reconstructs a super-resolved image from multiple raw images captured with different illumination patterns; hence, acquisition speed is limited, making it unsuitable for dynamic scenes. We propose a…

Optics · Physics 2025-06-17 Ruiming Cao , Fanglin Linda Liu , Li-Hao Yeh , Laura Waller

Optical spectroscopy plays an essential role across scientific research and industry for non-contact materials analysis1-3, increasingly through in-situ or portable platforms4-6. However, when considering low-light-level applications,…

In this paper we propose a very efficient method to fuse the unregistered multi-focus microscopical images based on the speed-up robust features (SURF). Our method follows the pipeline of first registration and then fusion. However, instead…

Computer Vision and Pattern Recognition · Computer Science 2020-01-20 Yixiong Liang , Yuan Mao , Zhihong Tang , Meng Yan , Yuqian Zhao , Jianfeng Liu
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