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The Quadratic Unconstrained Binary Optimization problem (QUBO) has become a unifying model for representing a wide range of combinatorial optimization problems, and for linking a variety of disciplines that face these problems. A new class…

Artificial Intelligence · Computer Science 2017-05-30 Mark Lewis , Fred Glover

Solving combinatorial optimization problems on current noisy quantum devices is currently being advocated for (and restricted to) binary polynomial optimization with equality constraints via quantum heuristic approaches. This is achieved…

Quantum Physics · Physics 2021-02-04 Claudio Gambella , Andrea Simonetto

In black-box combinatorial optimization, objective evaluations are often expensive, so high quality solutions must be found under a limited budget. Factorization machine with quantum annealing (FMQA) builds a quadratic surrogate model from…

Machine Learning · Computer Science 2026-02-11 Tetsuro Abe , Masashi Yamashita , Shu Tanaka

Quantum computing is developing fast. Real world applications are within reach in the coming years. One of the most promising areas is combinatorial optimisation, where the Quadratic Unconstrained Binary Optimisation (QUBO) problem…

Quantum Physics · Physics 2020-07-06 Frank Phillipson , Irina Chiscop

Quantum annealers offer a promising approach to solve Quadratic Unconstrained Binary Optimization (QUBO) problems, which have a wide range of applications. However, when a user submits its QUBO problem to a third-party quantum annealer, the…

Cryptography and Security · Computer Science 2024-09-30 Moyang Xie , Yuan Zhang , Sheng Zhong , Qun Li

Quantization of the parameters of machine learning models, such as deep neural networks, requires solving constrained optimization problems, where the constraint set is formed by the Cartesian product of many simple discrete sets. For such…

Optimization and Control · Mathematics 2021-03-02 Tianjian Huang , Prajwal Singhania , Maziar Sanjabi , Pabitra Mitra , Meisam Razaviyayn

Quantum annealing may provide advantages over simulated annealing on solving some problems such as Kth order binary optimization problem. No feasible architecture exists to implement the high-order optimization problem (K > 2) on current…

Quantum Physics · Physics 2016-05-13 Yong-Chao Tang , Guo-Xing Miao

Quantum annealing provides a practical realization of adiabatic quantum computation and has emerged as a promising approach for solving large-scale combinatorial optimization problems. However, current devices remain constrained by sparse…

Quantum Physics · Physics 2025-10-09 Seon-Geun Jeong , Mai Dinh Cong , Dae-Il Noh , Quoc-Viet Pham , Won-Joo Hwang

In the quest to reboot computing, quantum annealing (QA) is an interesting candidate for a new capability. While it has not demonstrated an advantage over classical computing on a real-world application, many important regions of the QA…

Discovering the low-energy conformations of a molecule is of great interest to computational chemists, with applications in {\em in silico} materials design and drug discovery. In this paper, we propose a variable neighbourhood search…

Quantum Physics · Physics 2019-06-25 D. J. J. Marchand , M. Noori , A. Roberts , G. Rosenberg , B. Woods , U. Yildiz , M. Coons , D. Devore , P. Margl

Quantum computing has emerged as a powerful potential accelerator for computational fluid dynamics (CFD), but whether this promise can be realized in practice depends on how fluid information is encoded on quantum hardware. This review…

Quantum Physics · Physics 2026-04-28 Omer Rathore , Alastair Basden , Nicholas Chancellor , Halim Kusumaatmaja

The performance of Quantum Autoencoders (QAEs) in anomaly detection tasks is critically dependent on the choice of data embedding and ansatz design. This study explores the effects of three data embedding techniques, data re-uploading,…

Quantum Physics · Physics 2024-09-10 Jack Y. Araz , Michael Spannowsky

In recent years, Variational Quantum Algorithms (VQAs) have emerged as a promising approach for solving optimization problems on quantum computers in the NISQ era. However, one limitation of VQAs is their reliance on fixed-structure…

Quantum Physics · Physics 2026-03-03 Gloria Turati , Maurizio Ferrari Dacrema , Paolo Cremonesi

Objective: Despite recent advancements in quantum computing, the limited number of available qubits has hindered progress in CT reconstruction. This study investigates the feasibility of utilizing quantum annealing-based computed tomography…

Quantum Physics · Physics 2024-02-12 Akihiro Haga

Constrained combinatorial optimization with strict linear constraints underpins applications in drug discovery, power grids, logistics, and finance, yet remains computationally demanding for classical algorithms, especially at large scales.…

Quantum Physics · Physics 2026-04-07 Yajie Hao , Qiming Ding , Xiao Yuan , Xiaoting Wang

Quantum adiabatic optimization seeks to solve combinatorial problems using quantum dynamics, requiring the Hamiltonian of the system to align with the problem of interest. However, these Hamiltonians are often incompatible with the native…

Quantum optimization is the most mature quantum computing technology to date, providing a promising approach towards efficiently solving complex combinatorial problems. Methods such as adiabatic quantum computing (AQC) have been employed in…

This study proposes a novel structural optimization framework based on quantum variational circuits, in which the multiplier acting on the cross-sectional area of each rod in a truss structure as an updater is used as a design variable.…

Quantum Physics · Physics 2025-02-25 Junsen Xiao , Naruethep Sukulthanasorn , Reika Nomura , Shuji Moriguchi , Kenjiro Terada

Solving optimisation problems is a promising near-term application of quantum computers. Quantum variational algorithms leverage quantum superposition and entanglement to optimise over exponentially large solution spaces using an…

Quantum Physics · Physics 2022-10-13 Edric Matwiejew , Jason Pye , Jingbo B. Wang

Several combinatorial optimization problems can be solved with NISQ devices once that a corresponding quadratic unconstrained binary optimization (QUBO) form is derived. The aim of this work is to drastically reduce the variables needed for…

Quantum Physics · Physics 2026-02-25 Dario De Santis , Salvatore Tirone , Stefano Marmi , Vittorio Giovannetti