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Intelligent metasurfaces may be harnessed for realizing efficient holographic multiple-input and multiple-output (MIMO) systems, at a low hardware-cost and high energy-efficiency. As part of this family, we propose a hybrid beamforming…

Information Theory · Computer Science 2025-02-18 Qingchao Li , Mohammed El-Hajjar , Chao Xu , Jiancheng An , Chau Yuen , Lajos Hanzo

Virtual staining has emerged as a powerful alternative to traditional histopathological staining techniques, enabling rapid, reagent-free image transformations. However, existing evaluation methods predominantly rely on full-reference image…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Qiankai Wang , James E. D. Tweel , Parsin Haji Reza , Anita Layton

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

Multi-modal medical image fusion (MMIF) is increasingly recognized as an essential technique for enhancing diagnostic precision and facilitating effective clinical decision-making within computer-aided diagnosis systems. MMIF combines data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Muhammad Zubair , Muzammil Hussai , Mousa Ahmad Al-Bashrawi , Malika Bendechache , Muhammad Owais

Modern histopathology relies on the microscopic examination of thin tissue sections stained with histochemical techniques, typically using brightfield or fluorescence microscopy. However, the staining of samples can permanently alter their…

Here, we present a diffusion transformer (DiT)-based pixel super-resolution virtual staining approach to transform low-resolution FTIR microspectroscopic images of the unstained tissues into corresponding high-resolution H&E-stained images.…

Optics · Physics 2026-03-10 Yudong Tian , Xiangyu Zhao , Yuqing Liu , Bofei Yang , Chongzhao Wu

Multimodal image fusion enables precise lesion localization and characterization for accurate diagnosis, thereby strengthening clinical decision-making and driving its growing prominence in medical imaging research. A powerful multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Jie Song , Jun Jia , Wei Sun , Wangqiu Zhou , Tao Tan , Guangtao Zhai

Quantitative image analysis often depends on accurate classification of pixels through a segmentation process. However, imaging artifacts such as the partial volume effect and sensor noise complicate the classification process. These…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Brendan A. West , Taylor S. Hodgdon , Matthew D. Parno , Arnold J. Song

Three-dimensional X-ray histology techniques offer a non-invasive alternative to conventional 2D histology, enabling volumetric imaging of biological tissues without the need for physical sectioning or chemical staining. However, the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Sarah C. Irvine , Christian Lucas , Diana Krüger , Bianca Guedert , Julian Moosmann , Berit Zeller-Plumhoff

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

Deep learning has shown promising contributions in medical image segmentation with powerful learning and feature representation abilities. However, it has limitations for reasoning with and combining imperfect (imprecise, uncertain, and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Ling Huang

Immunohistochemistry is a valuable diagnostic tool for cancer pathology. However, it requires specialist labs and equipment, is time-intensive, and is difficult to reproduce. Consequently, a long term aim is to provide a digital method of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Christopher D. Walsh , Joanne Edwards , Robert H. Insall

Fluorescence Lifetime Imaging (FLI) is a critical molecular imaging modality that provides unique information about the tissue microenvironment, which is invaluable for biomedical applications. FLI operates by acquiring and analyzing photon…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Ismail Erbas , Vikas Pandey , Navid Ibtehaj Nizam , Nanxue Yuan , Amit Verma , Margarida Barosso , Xavier Intes

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Widely adopted medical image segmentation methods, although efficient, are primarily deterministic and remain poorly amenable to natural language prompts. Thus, they lack the capability to estimate multiple proposals, human interaction, and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Yuan Lin , Murong Xu , Marc Hölle , Chinmay Prabhakar , Andreas Maier , Vasileios Belagiannis , Bjoern Menze , Suprosanna Shit

In clinical practice, full imaging is not always feasible, often due to complex acquisition protocols, stringent privacy regulations, or specific clinical needs. However, missing MR modalities pose significant challenges for tasks like…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

The integrity of the reconstructed human epidermis generated in vitro could be assessed using histological analyses combined with immunohistochemical staining of keratinocyte differentiation markers. Computer-based analysis of scanned…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Dawid Zamojski , Agnieszka Gogler , Dorota Scieglinska , Michal Marczyk

Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Muyi Sun , Zeyi Yao , Guanhong Zhang

Synthesizing medical images while preserving their structural information is crucial in medical research. In such scenarios, the preservation of anatomical content becomes especially important. Although recent advances have been made by…

Image and Video Processing · Electrical Eng. & Systems 2024-11-14 Ziqi Yu , Botao Zhao , Shengjie Zhang , Xiang Chen , Jianfeng Feng , Tingying Peng , Xiao-Yong Zhang

Multi-modal image fusion (MMIF) maps useful information from various modalities into the same representation space, thereby producing an informative fused image. However, the existing fusion algorithms tend to symmetrically fuse the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Jingxue Huang , Xilai Li , Tianshu Tan , Xiaosong Li , Tao Ye