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Evaluating quantum algorithms at utility-scale - involving more than 100 qubits - is a key step toward advancing real-world applications of quantum computing. In this study, we benchmark seven state-of-the-art quantum emulators employing…

We study large-scale applications using a GPU-accelerated version of the massively parallel J\"ulich universal quantum computer simulator (JUQCS--G). First, we benchmark JUWELS Booster, a GPU cluster with 3744 NVIDIA A100 Tensor Core GPUs.…

Quantum Physics · Physics 2022-05-17 Dennis Willsch , Madita Willsch , Fengping Jin , Kristel Michielsen , Hans De Raedt

Combinatorial optimization on near-term quantum devices is a promising path to demonstrating quantum advantage. However, the capabilities of these devices are constrained by high noise or error rates. In this paper, we propose an iterative…

Quantum Physics · Physics 2022-05-12 Xiaoyuan Liu , Anthony Angone , Ruslan Shaydulin , Ilya Safro , Yuri Alexeev , Lukasz Cincio

We present a framework for effectively simulating the execution of quantum circuits originally designed to demonstrate quantum supremacy using accessible high-performance computing (HPC) infrastructure. Building on prior CPU-only…

Quantum Physics · Physics 2025-12-09 Bob Wold , Venkateswaran Kasirajan

Quantum computers offer a promising route to tackling problems that are classically intractable such as in prime-factorization, solving large-scale linear algebra and simulating complex quantum systems, but potentially require…

As quantum hardware advances toward fault-tolerant operation, an intermediate stage known as early fault-tolerant quantum computing (EFTQC) is emerging, where partial error correction enables meaningful computation. In this regime, the…

Quantum Physics · Physics 2025-11-14 Yanbing Zhou , Athena Caesura , Corneliu Buda , Xavier Jackson , Clena M. Abuan , Shangjie Guo

Recent hardware acceleration advances have enabled powerful specialized accelerators for finite element computations, spiking neural network inference, and sparse tensor operations. However, existing approaches face fundamental limitations:…

Hardware Architecture · Computer Science 2026-01-09 Chuanzhen Wang , Leo Zhang , Eric Liu

Cloud-accessible quantum processors enable direct execution of quantum algorithms on heterogeneous hardware platforms. Unlike classical systems, however, identical quantum circuits may exhibit substantially different behavior across devices…

Quantum Physics · Physics 2026-01-12 Askar Oralkhan , Temirlan Zhaxalykov

FPGAs offer high performance, low latency, and energy efficiency for accelerated computing, yet adoption in scientific and edge settings is limited by the specialized hardware expertise required. High-level synthesis (HLS) boosts…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-09 Maxim Moraru , Kamalavasan Kamalakkannan , Jered Dominguez-Trujillo , Patrick Diehl , Atanu Barai , Julien Loiseau , Zachary Kent Baker , Howard Pritchard , Galen M Shipman

AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

We present a framework that utilizes quantum algorithms, an architecture aware quantum noise model and an ideal simulator to benchmark quantum computers. The benchmark metrics highlight the difference between the quantum computer evolution…

Quantum Physics · Physics 2021-12-20 Konstantinos Georgopoulos , Clive Emary , Paolo Zuliani

This paper describes the main features of a pioneering unsteady solver for simulating ideal two-fluid plasmas on unstructured grids, taking profit of GPGPU (General-purpose computing on graphics processing units). The code, which has been…

We present a comprehensive end-to-end quantum algorithm for tensor problems, including tensor PCA and planted kXOR, that achieves potential superquadratic quantum speedups over classical methods. We build upon prior works by…

Simulating dynamics of physical systems is a key application of quantum computing, with potential impact in fields such as condensed matter physics and quantum chemistry. However, current quantum algorithms for Hamiltonian simulation yield…

The Quantum Approximate Optimization Algorithm (QAOA) is a prominent quantum algorithm designed to find approximate solutions to combinatorial optimization problems, which are challenging for classical computers. In the current era, where…

Important computational physics problems are often large-scale in nature, and it is highly desirable to have robust and high performing computational frameworks that can quickly address these problems. However, it is no trivial task to…

Mathematical Software · Computer Science 2017-09-18 J. Chang , K. B. Nakshatrala , M. G. Knepley , L. Johnsson

To harness the potential of advanced computing technologies, efficient (real time) analysis of large amounts of data is as essential as are front-line simulations. In order to optimise this process, experts need to be supported by…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-03 Jovana Knežević , Ralf-Peter Mundani , Ernst Rank

Quantum computing algorithms have been shown to produce performant quantum kernels for machine-learning classification problems. Here, we examine the performance of quantum kernels for regression problems of practical interest. For an…

Quantum Physics · Physics 2024-09-30 Xuyang Guo , Jun Dai , Roman V. Krems

State-of-the-art noisy intermediate-scale quantum devices (NISQ), although imperfect, enable computational tasks that are manifestly beyond the capabilities of modern classical supercomputers. However, present quantum computations are…

Advances in quantum simulator technology is increasingly required because research on quantum algorithms is becoming more sophisticated and complex. State vector simulation utilizes CPU and memory resources in computing nodes exponentially…

Quantum Physics · Physics 2024-09-04 Mikio Morita , Yoshinori Tomita , Junpei Koyama , Koichi Kimura
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