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In the near future, massively parallel computing systems will be necessary to solve computation intensive applications. The key bottleneck in massively parallel implementation of numerical algorithms is the synchronization of data across…

Systems and Control · Computer Science 2015-03-16 Kooktae Lee , Raktim Bhattacharya , Vijay Gupta

Finite-sum optimization has wide applications in machine learning, covering important problems such as support vector machines, regression, etc. In this paper, we initiate the study of solving finite-sum optimization problems by quantum…

Quantum Physics · Physics 2024-06-06 Yexin Zhang , Chenyi Zhang , Cong Fang , Liwei Wang , Tongyang Li

Accurately predicting protein-ligand binding free energies (BFEs) remains a central challenge in drug discovery, particularly because the most reliable methods, such as free energy perturbation (FEP), are computationally intensive and…

Chemical Physics · Physics 2025-12-09 Farzad Molani , Art E. Cho

The number of measurements demanded by hybrid quantum-classical algorithms such as the variational quantum eigensolver (VQE) is prohibitively high for many problems of practical value. For such problems, realizing quantum advantage will…

Quantum Physics · Physics 2021-03-24 Guoming Wang , Dax Enshan Koh , Peter D. Johnson , Yudong Cao

Simulating molecular systems on quantum processors has the potential to surpass classical methods in computational resource efficiency. The limited qubit connectivity, small processor size, and short coherence times of near-term quantum…

Quantum Physics · Physics 2025-04-08 Abhishek Sadhu , Aritra Sarkar , Akash Kundu

FPGAs have been shown to be a promising platform for deploying Quantised Neural Networks (QNNs) with high-speed, low-latency, and energy-efficient inference. However, the complexity of modern deep-learning models limits the performance on…

Hardware Architecture · Computer Science 2025-11-06 Changhong Li , Biswajit Basu , Shreejith Shanker

Performance tests and analyses are critical to effective HPC software development and are central components in the design and implementation of computational algorithms for achieving faster simulations on existing and future computing…

One of the major problems of most quantum computing applications is that the required number of qubits to solve a practical problem is much larger than that of today's quantum hardware. We propose an algorithm, called large-system sampling…

Quantum Physics · Physics 2022-08-08 Chen-Yu Liu , Hsi-Sheng Goan

Toward quantum machine learning deployed on imperfect near-term intermediate-scale quantum (NISQ) processors, the entire physical implementation of should include as less as possible hand-designed modules with only a few ad-hoc parameters…

Quantum Physics · Physics 2021-01-04 Re-Bing Wu , Xi Cao , Pinchen Xie , Yu-xi Liu

Quantum algorithms can deliver asymptotic speedups over their classical counterparts. However, there are few cases where a substantial quantum speedup has been worked out in detail for reasonably-sized problems, when compared with the best…

Quantum Physics · Physics 2019-07-24 Earl Campbell , Ankur Khurana , Ashley Montanaro

Quantum annealing offers a promising paradigm for solving NP-hard combinatorial optimization problems, but its practical application is severely hindered by two challenges: the complex, manual process of translating problem descriptions…

Machine Learning · Computer Science 2025-09-03 Huixiang Zhang , Mahzabeen Emu , Salimur Choudhury

Quantum approximate optimization algorithm (QAOA) is one of the popular quantum algorithms that are used to solve combinatorial optimization problems via approximations. QAOA is able to be evaluated on both physical and virtual quantum…

Quantum Physics · Physics 2023-12-07 Yu-Cheng Lin , Chuan-Chi Wang , Chia-Heng Tu , Shih-Hao Hung

We introduce CaLES, a GPU-accelerated finite-difference solver designed for large-eddy simulations (LES) of incompressible wall-bounded flows in massively parallel environments. Built upon the existing direct numerical simulation (DNS)…

Fluid Dynamics · Physics 2024-11-18 Maochao Xiao , Alessandro Ceci , Pedro Costa , Johan Larsson , Sergio Pirozzoli

Quantum error correction (QEC) is essential for achieving low error rates required for fault-tolerant quantum computation. In stabilizer-based codes such as the surface code, errors are inferred from repeated syndrome measurements and…

Variational quantum algorithm (VQA), which is comprised of a classical optimizer and a parameterized quantum circuit, emerges as one of the most promising approaches for harvesting the power of quantum computers in the noisy intermediate…

Quantum Physics · Physics 2021-12-01 Samuel Stein , Yufei Ding , Nathan Wiebe , Bo Peng , Karol Kowalski , Nathan Baker , James Ang , Ang Li

Modern machine learning workloads such as large language model training, fine-tuning jobs are highly distributed and span across hundreds of systems with multiple GPUs. Job completion time for these workloads is the artifact of the…

Networking and Internet Architecture · Computer Science 2025-07-08 Jit Gupta , Tarun Banka , Rahul Gupta , Mithun Dharmaraj , Jasleen Kaur

This paper presents a workflow for synthesizing near-optimal FPGA implementations for structured-mesh based stencil applications for explicit solvers. It leverages key characteristics of the application class, its computation-communication…

Hardware Architecture · Computer Science 2021-01-08 Kamalavasan Kamalakkannan , Gihan R. Mudalige , Istvan Z. Reguly , Suhaib A. Fahmy

The Quantum Approximate Optimization Algorithm (QAOA) is a leading approach for solving combinatorial optimization problems on near-term quantum processors. However, finding good variational parameters remains a significant challenge due to…

Quantum Physics · Physics 2025-12-05 Yu-Cheng Lin , Yu-Chao Hsu , Samuel Yen-Chi Chen

This research explores the integration of quantum data embedding techniques into classical machine learning (ML) algorithms, aiming to assess the performance enhancements and computational implications across a spectrum of models. We…

Quantum Physics · Physics 2023-11-20 Minati Rath , Hema Date

High-performance techniques to simulate quantum programs on classical hardware rely on exponentially large vectors to represent quantum states. When simulating quantum algorithms, the quantum states that occur are often sparse due to…

Quantum Physics · Physics 2021-05-05 Samuel Jaques , Thomas Häner
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