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Brain age gap estimation (BrainAGE) is a promising imaging-derived biomarker of neurobiological aging and disease risk, yet current approaches rely predominantly on T1-weighted structural MRI (T1w), overlooking functional vascular changes…

Image and Video Processing · Electrical Eng. & Systems 2025-12-10 Jordan Jomsky , Kay C. Igwe , Zongyu Li , Yiren Zhang , Max Lashley , Tal Nuriel , Andrew Laine , Jia Guo

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…

Machine Learning · Computer Science 2025-01-06 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

The unprecedented extension of the human lifespan necessitates a parallel evolution in how we quantify the quality of aging and its socioeconomic impact. Traditional metrics focusing on Healthspan (years free of disease) overlook the…

Quantitative Methods · Quantitative Biology 2026-03-19 Alex Zhavoronkov , Dominika Wilczok

Achieving high performance for facial age estimation with subjects in the borderline between adulthood and non-adulthood has always been a challenge. Several studies have used different approaches from the age of a baby to an elder adult…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Felix Anda , David Lillis , Aikaterini Kanta , Brett A. Becker , Elias Bou-Harb , Nhien-An Le-Khac , Mark Scanlon

Photolethysmographic imaging (PPGI) is a widefield non-contact biophotonic technology able to remotely monitor cardiovascular function over anatomical areas. Though spatial context can provide increased physiological insight, existing PPGI…

Quantitative Methods · Quantitative Biology 2016-12-21 Robert Amelard , David A Clausi , Alexander Wong

Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability…

Neurons and Cognition · Quantitative Biology 2024-04-04 James K Ruffle , Robert J Gray , Samia Mohinta , Guilherme Pombo , Chaitanya Kaul , Harpreet Hyare , Geraint Rees , Parashkev Nachev

As we gain access to a greater depth and range of health-related information about individuals, three questions arise: (1) Can we build better models to predict individual-level risk of ill health? (2) How much data do we need to…

Machine Learning · Statistics 2021-04-27 Mark Green

Modern wearable devices can conveniently record various biosignals in the many different environments of daily living, enabling a rich view of individual health. However, not all biosignals are the same: high-fidelity biosignals, such as…

Machine Learning · Computer Science 2025-02-03 Salar Abbaspourazad , Anshuman Mishra , Joseph Futoma , Andrew C. Miller , Ian Shapiro

Tracking biosignals is crucial for monitoring wellness and preempting the development of severe medical conditions. Today, wearable devices can conveniently record various biosignals, creating the opportunity to monitor health status…

Machine Learning · Computer Science 2024-03-07 Salar Abbaspourazad , Oussama Elachqar , Andrew C. Miller , Saba Emrani , Udhyakumar Nallasamy , Ian Shapiro

Bone age assessment (BAA) is a standard method for determining the age difference between skeletal and chronological age. Manual processes are complicated and necessitate the expertise of experts. This is where deep learning comes into…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Aravinda Raman , Sameena Pathan , Tanweer Ali

High-frequency physiological waveform modality offers deep, real-time insights into patient status. Recently, physiological foundation models based on Photoplethysmography (PPG), such as PPG-GPT, have been shown to predict critical events,…

Machine Learning · Computer Science 2025-09-29 Saurabh Kataria , Davood Fattahi , Minxiao Wang , Ran Xiao , Matthew Clark , Timothy Ruchti , Mark Mai , Xiao Hu

Blood Pressure (BP) is one of the four primary vital signs indicating the status of the body's vital (life-sustaining) functions. BP is difficult to continuously monitor using a sphygmomanometer (i.e. a blood pressure cuff), especially in…

Machine Learning · Computer Science 2021-08-03 Ali Tazarv , Marco Levorato

Self-supervised foundation models have recently been successfully extended to encode three-dimensional (3D) computed tomography (CT) images, with excellent performance across several downstream tasks, such as intracranial hemorrhage…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Guangyao Zheng , Michael A. Jacobs , Vishwa S. Parekh

Biometric authentication prospered because of its convenient use and security. Early generations of biometric mechanisms suffer from spoofing attacks. Recently, unobservable physiological signals (e.g., Electroencephalogram,…

Cryptography and Security · Computer Science 2024-01-29 Lin Li , Chao Chen , Lei Pan , Leo Yu Zhang , Zhifeng Wang , Jun Zhang , Yang Xiang

This study developed an accurate artificial intelligence model for predicting future height in children and adolescents using anthropometric and body composition data from the GP Cohort Study (588,546 measurements from 96,485 children aged…

Quantitative Methods · Quantitative Biology 2025-04-10 Dohyun Chun , Hae Woon Jung , Jongho Kang , Woo Young Jang , Jihun Kim

Photoplethysmography (PPG) is a non-invasive technology that measures changes in blood volume in the microvascular bed of tissue. It is commonly used in medical devices such as pulse oximeters and wrist worn heart rate monitors to monitor…

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Benjamin Gutierrez Becker , Tassilo Klein , Christian Wachinger

Radiologists and doctors make use of X-ray images of the non-dominant hands of children and infants to assess the possibility of genetic conditions and growth abnormalities. This is done by assessing the difference between the actual extent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Nandavardhan R. , Somanathan R. , Vikram Suresh , Savaridassan P

Face-based age estimation has attracted enormous attention due to wide applications to public security surveillance, human-computer interaction, etc. With vigorous development of deep learning, age estimation based on deep neural network…

Computer Vision and Pattern Recognition · Computer Science 2022-05-23 Zhicheng Cao , Kaituo Zhang , Liaojun Pang , Heng Zhao

In order to obtain insights into the feasibility of replacing ECG-guided triggering in magnetic resonance imaging (MRI) by a system based on video photoplethysmography (PPG), PPG and ECG data were collected from volunteers in an MRI…

Signal Processing · Electrical Eng. & Systems 2023-06-19 A. C. den Brinker , H. H. Der Sarkissian , J. H. Wülbern , B. Balmaekers , M. Padalko , J. Sénégas , R. Springorum , C. Possanzini