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Epigenetics is the study of how people's behavior and environments influence the way their genes are expressed, even though their DNA sequence is itself unchanged. By aggregating age-related epigenetic markers, epigenetic 'clocks' have…

General Economics · Economics 2025-09-19 Giorgia Menta , Pietro Biroli , Divya Mehta , Conchita D'Ambrosio , Deborah Cobb-Clark

Author's early work on aging is developed to yield a relationship between life spans and the velocity of aging. The mathematical analysis shows that the mean extent of the advancement of aging throughout one's life is conserved, or…

Populations and Evolution · Quantitative Biology 2007-05-23 Kazumi Suematsu

Most of today's wearable technology provides seamless cardiac activity monitoring. Specifically, the vast majority employ Photoplethysmography (PPG) sensors to acquire blood volume pulse information, which is further analysed to extract…

Human-Computer Interaction · Computer Science 2023-09-26 Jose A. Miranda , Celia López-Ongil , Javier Andreu-Perez

Older adults often experience increased difficulty in decision making due to age-related declines particularly in contexts that require information search or the generation of alternatives from memory. This study examined whether using…

Human-Computer Interaction · Computer Science 2025-12-05 Sayaka Ishibashi , Kou Tamura , Ayana Goma , Kenta Yamamoto , Kouhei Masumoto

The chronological age used in demography describes the linear evolution of the life of a living being. The chronological age cannot give precise information about the exact developmental stage or aging processes an organism has reached. On…

Analysis of PDEs · Mathematics 2023-10-02 Jacques Demongeot , Pierre Magal

Camera-based monitoring of vital signs, also known as imaging photoplethysmography (iPPG), has seen applications in driver-monitoring, perfusion assessment in surgical settings, affective computing, and more. iPPG involves sensing the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Vineet R Shenoy , Suhas Lohit , Hassan Mansour , Rama Chellappa , Tim K. Marks

EEG foundation models are typically pretrained on narrow-source clinical archives and evaluated on benchmarks from the same ecosystem, leaving unclear whether representations encode neural physiology or recording-distribution artifacts. We…

In computational neuroscience, there has been an increased interest in developing machine learning algorithms that leverage brain imaging data to provide estimates of "brain age" for an individual. Importantly, the discordance between brain…

Quantitative Methods · Quantitative Biology 2023-10-30 Saurabh Sihag , Gonzalo Mateos , Corey McMillan , Alejandro Ribeiro

Objective: fMRI and derived measures such as functional connectivity (FC) have been used to predict brain age, general fluid intelligence, psychiatric disease status, and preclinical neurodegenerative disease. However, it is not always…

Quantitative Methods · Quantitative Biology 2024-05-14 Anton Orlichenko , Gang Qu , Ziyu Zhou , Anqi Liu , Hong-Wen Deng , Zhengming Ding , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Age is an essential factor in modern diagnostic procedures. However, assessment of the true biological age (BA) remains a daunting task due to the lack of reference ground-truth labels. Current BA estimation approaches are either restricted…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Tobias Hepp , Sergios Gatidis , Bin Yang

Early detection of surgical complications allows for timely therapy and proactive risk mitigation. Machine learning (ML) can be leveraged to identify and predict patient risks for postoperative complications. We developed and validated the…

Machine Learning · Computer Science 2024-12-31 Junbo Shen , Bing Xue , Thomas Kannampallil , Chenyang Lu , Joanna Abraham

Predictive modeling using structural magnetic resonance imaging (MRI) data is a prominent approach to study brain-aging. Machine learning algorithms and feature extraction methods have been employed to improve predictions and explore…

Machine Learning · Computer Science 2025-01-20 Georgios Antonopoulos , Shammi More , Simon B. Eickhoff , Federico Raimondo , Kaustubh R. Patil

Fetal ultrasounds are an essential part of prenatal care and can be used to estimate gestational age (GA). Accurate GA assessment is important for providing appropriate prenatal care throughout pregnancy and identifying complications such…

In order to develop infocommunications devices so that the capabilities of the human brain may interact with the capabilities of any artificially cognitive system a deeper knowledge of aging is necessary. Especially if society does not want…

Human-Computer Interaction · Computer Science 2022-03-09 Marcos Faundez-Zanuy , Enric Sesa-Nogueras , Josep Roure-Alcobé , Anna Esposito , Jiri Mekyska , Karmele López-de-Ipiña

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Machine learning has been widely used in healthcare applications to approximate complex models, for clinical diagnosis, prognosis, and treatment. As deep learning has the outstanding ability to extract information from time series, its true…

Machine Learning · Computer Science 2022-11-14 Ke Liao , Wei Wang , Armagan Elibol , Lingzhong Meng , Xu Zhao , Nak Young Chong

Will the United Kingdom's ageing population be fit and independent, or suffer from greater chronic ill health? Healthy life expectancy is commonly used to assess this: it is an estimate of how many years are lived in good health over the…

Statistics Theory · Mathematics 2007-06-13 Ehsan Khoman , Martin Weale

In the Performance-Based Engineering (PBE) framework, uncertainties in system parameters, or modelling uncertainties, have been shown to have significant effects on capacity fragilities and annual collapse rates of buildings. Yet, since…

Optimization and Control · Mathematics 2022-10-17 Andre T. Beck , Rubia M. Bosse , Isabela D. Rodrigues

Heartbeat rhythm and heart rate (HR) are important physiological parameters of the human body. This study presents an efficient multi-hierarchical spatio-temporal convolutional network that can quickly estimate remote physiological (rPPG)…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Bin Li , Panpan Zhang , Jinye Peng , Hong Fu

Much of the information of breathing is contained within the photoplethysmography (PPG) signal, through changes in venous blood flow, heart rate and stroke volume. We aim to leverage this fact, by employing a novel deep learning framework…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Harry J. Davies , Danilo P. Mandic
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