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Ensuring the generalisability of clinical machine learning (ML) models across diverse healthcare settings remains a significant challenge due to variability in patient demographics, disease prevalence, and institutional practices. Existing…

Machine Learning · Computer Science 2025-04-30 Bradley Segal , Joshua Fieggen , David Clifton , Lei Clifton

Machine learning methods can be unreliable when deployed in domains that differ from the domains on which they were trained. There are a wide range of proposals for mitigating this problem by learning representations that are ``invariant''…

Machine Learning · Statistics 2023-02-09 Zihao Wang , Victor Veitch

For time series arising from latent dynamical systems, existing cross-domain generalization methods commonly assume that samples are comparably meaningful within a shared representation space. In real-world settings, however, different…

Machine Learning · Computer Science 2026-03-04 Jinyang Li , Shuhao Mei , Xiaoyu Xiao , Shuhang Li , Ruoxi Yun , Jinbo Sun

The distribution shifts between training and test data typically undermine the performance of models. In recent years, lots of work pays attention to domain generalization (DG) where distribution shifts exist, and target data are unseen.…

Machine Learning · Computer Science 2024-01-05 Wang Lu , Jindong Wang , Yidong Wang , Xing Xie

In medical image analysis, model predictions can be affected by sensitive attributes, such as race and gender, leading to fairness concerns and potential biases in diagnostic outcomes. To mitigate this, we present a causal modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Bowei Tian , Yexiao He , Meng Liu , Yucong Dai , Ziyao Wang , Shwai He , Guoheng Sun , Zheyu Shen , Wanghao Ye , Yongkai Wu , Ang Li

The absence of well-structured large datasets in medical computer vision results in decreased performance of automated systems and, especially, of deep learning models. Domain generalization techniques aim to approach unknown domains from a…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Nikolaos Spanos , Anastasios Arsenos , Paraskevi-Antonia Theofilou , Paraskevi Tzouveli , Athanasios Voulodimos , Stefanos Kollias

Causal theory is now widely developed with many applications to medicine and public health. However within the discipline of reliability, although causation is a key concept in this field, there has been much less theoretical attention. In…

Artificial Intelligence · Computer Science 2020-02-17 Xuewen Yu , Jim Q. Smith , Linda Nichols

In this work, we propose a domain generalization (DG) approach to learn on several labeled source domains and transfer knowledge to a target domain that is inaccessible in training. Considering the inherent conditional and label shifts, we…

Machine Learning · Computer Science 2021-07-26 Xiaofeng Liu , Bo Hu , Linghao Jin , Xu Han , Fangxu Xing , Jinsong Ouyang , Jun Lu , Georges EL Fakhri , Jonghye Woo

A major challenge in research involving artificial intelligence (AI) is the development of algorithms that can find solutions to problems that can generalize to different environments and tasks. Unlike AI, humans are adept at finding…

Artificial Intelligence · Computer Science 2021-10-12 Semir Tatlidil , Yanqi Liu , Emily Sheetz , R. Iris Bahar , Steven Sloman

Domain generalization aims to apply knowledge gained from multiple labeled source domains to unseen target domains. The main difficulty comes from the dataset bias: training data and test data have different distributions, and the training…

Machine Learning · Computer Science 2018-07-24 Ya Li , Mingming Gong , Xinmei Tian , Tongliang Liu , Dacheng Tao

Causal inference is a science with multi-disciplinary evolution and applications. On the one hand, it measures effects of treatments in observational data based on experimental designs and rigorous statistical inference to draw causal…

Methodology · Statistics 2022-09-05 Jingying Zeng , Run Wang

In application domains such as healthcare, we want accurate predictive models that are also causally interpretable. In pursuit of such models, we propose a causal regularizer to steer predictive models towards causally-interpretable…

Machine Learning · Computer Science 2017-02-24 Mohammad Taha Bahadori , Krzysztof Chalupka , Edward Choi , Robert Chen , Walter F. Stewart , Jimeng Sun

Current approaches which are mainly based on the extraction of low-level relations among individual events are limited by the shortage of publicly available labelled data. Therefore, the resulting models perform poorly when applied to a…

Computation and Language · Computer Science 2020-11-30 Farhad Moghimifar , Gholamreza Haffari , Mahsa Baktashmotlagh

Reward modelling from preference data is a crucial step in aligning large language models (LLMs) with human values, requiring robust generalisation to novel prompt-response pairs. In this work, we propose to frame this problem in a causal…

Artificial Intelligence · Computer Science 2026-05-12 Katarzyna Kobalczyk , Mihaela van der Schaar

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

Ensuring trustworthiness in machine learning (ML) systems is crucial as they become increasingly embedded in high-stakes domains. This paper advocates for integrating causal methods into machine learning to navigate the trade-offs among key…

Machine Learning · Computer Science 2026-03-16 Ruta Binkyte , Ivaxi Sheth , Zhijing Jin , Mohammad Havaei , Bernhard Schölkopf , Mario Fritz

Real-world classification problems must contend with domain shift, the (potential) mismatch between the domain where a model is deployed and the domain(s) where the training data was gathered. Methods to handle such problems must specify…

Machine Learning · Computer Science 2022-07-05 Yibo Jiang , Victor Veitch

Domain generalization refers to the problem where we aim to train a model on data from a set of source domains so that the model can generalize to unseen target domains. Naively training a model on the aggregate set of data (pooled from all…

Machine Learning · Computer Science 2022-02-16 A. Tuan Nguyen , Toan Tran , Yarin Gal , Atılım Güneş Baydin

Mathematical models are fundamental building blocks in the design of dynamical control systems. As control systems are becoming increasingly complex and networked, approaches for obtaining such models based on first principles reach their…

Machine Learning · Computer Science 2022-07-19 Dominik Baumann , Friedrich Solowjow , Karl H. Johansson , Sebastian Trimpe

Causal inference is a central goal across many scientific disciplines. Over the past several decades, three major frameworks have emerged to formalize causal questions and guide their analysis: the potential outcomes framework, structural…

Statistics Theory · Mathematics 2026-02-12 Linbo Wang , Thomas Richardson , James Robins