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Spatial transcriptomics enables gene expression profiling with spatial context, offering unprecedented insights into the tissue microenvironment. However, most computational models treat genes as isolated numerical features, ignoring the…

Machine Learning · Computer Science 2025-11-17 Jiangkai Long , Yanran Zhu , Chang Tang , Kun Sun , Yuanyuan Liu , Xuesong Yan

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

Advances in spatial transcriptomics (ST) technologies enable systematic molecular characterization of tumor microenvironment, tumor gradients and gene regulatory networks. Cancer progression is known to vary along pathological gradients,…

Self-supervised pretraining has become the mainstream approach for learning MRI representations from unlabeled scans. However, most existing objectives still treat each scan primarily as static aggregations of slices, patches or volumes. We…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Yu Wang , Qingchao Chen

Spatial transcriptomics clustering is pivotal for identifying cell subpopulations by leveraging spatial location information. While recent graph-based methods modeling cell-cell interactions have improved clustering accuracy, they remain…

Machine Learning · Computer Science 2026-01-21 Chenkai Guo , Yikai Zhu , Renxiang Guan , Jinli Ma , Siwei Wang , Ke Liang , Guangdun Peng , Dayu Hu

We present streaming self-training (SST) that aims to democratize the process of learning visual recognition models such that a non-expert user can define a new task depending on their needs via a few labeled examples and minimal domain…

Computer Vision and Pattern Recognition · Computer Science 2021-04-08 Zhiqiu Lin , Deva Ramanan , Aayush Bansal

Spatial transcriptomics provides a molecularly rich description of tissue organization, enabling unsupervised discovery of tissue niches -- spatially coherent regions of distinct cell-type composition and function that are relevant to both…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Arbel Hizmi , Artemii Bakulin , Shai Bagon , Nir Yosef

Spatial transcriptomics (ST) enables spatially resolved gene profiling but remains expensive and low-throughput, limiting large-cohort studies and routine clinical use. Predicting spatial gene expression from routine hematoxylin and eosin…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Changfan Wang , Xinran Wang , Donghai Liu , Fei Su , Lulu Sun , Zhicheng Zhao , Zhu Meng

We introduce SPECTRE, a fully transformer-based foundation model for volumetric computed tomography (CT). Our Self-Supervised & Cross-Modal Pretraining for CT Representation Extraction (SPECTRE) approach utilizes scalable 3D Vision…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Cris Claessens , Christiaan Viviers , Giacomo D'Amicantonio , Egor Bondarev , Fons van der Sommen

Hyperspectral image super-resolution has attained widespread prominence to enhance the spatial resolution of hyperspectral images. However, convolution-based methods have encountered challenges in harnessing the global spatial-spectral…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Shi Chen , Lefei Zhang , Liangpei Zhang

Pre-training on large-scale video data has become a common recipe for learning transferable spatiotemporal representations in recent years. Despite some progress, existing methods are mostly limited to highly curated datasets (e.g., K400)…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Ziyun Zeng , Yuying Ge , Xihui Liu , Bin Chen , Ping Luo , Shu-Tao Xia , Yixiao Ge

In recent years, there has been a rapid development of spatio-temporal prediction techniques in response to the increasing demands of traffic management and travel planning. While advanced end-to-end models have achieved notable success in…

Machine Learning · Computer Science 2023-11-09 Zhonghang Li , Lianghao Xia , Yong Xu , Chao Huang

Self-supervised learning (SSL) methods have become a dominant paradigm for creating general purpose models whose capabilities can be transferred to downstream supervised learning tasks. However, most such methods rely on vast amounts of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Lakshay Sharma , Alex Marin

Spatial-temporal (ST) graph modeling, such as traffic speed forecasting and taxi demand prediction, is an important task in deep learning area. However, for the nodes in graph, their ST patterns can vary greatly in difficulties for…

Machine Learning · Computer Science 2022-11-29 Hongjun Wang , Jiyuan Chen , Tong Pan , Zipei Fan , Boyuan Zhang , Renhe Jiang , Lingyu Zhang , Yi Xie , Zhongyi Wang , Xuan Song

Achieving 3D spatial awareness is crucial for surgical robotic manipulation, where precise and delicate operations are required. Existing methods either explicitly reconstruct the surgical scene prior to manipulation, or enhance multi-view…

Robotics · Computer Science 2026-03-05 Yu Sheng , Lidian Wang , Xiaomeng Chu , Jiajun Deng , Min Cheng , Yanyong Zhang , Bei Hua , Houqiang Li , Jianmin Ji

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

Spatio-Temporal predictive Learning is a self-supervised learning paradigm that enables models to identify spatial and temporal patterns by predicting future frames based on past frames. Traditional methods, which use recurrent neural…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Andrea Alfarano , Alberto Alfarano , Linda Friso , Andrea Bacciu , Irene Amerini , Fabrizio Silvestri

Spatio-temporal forecasting is fundamental to intelligent systems in transportation, climate science, and urban planning. However, training deep learning models on the massive, often redundant, datasets from these domains presents a…

Machine Learning · Computer Science 2026-03-03 Wei Chen , Junle Chen , Yuqian Wu , Yuxuan Liang , Xiaofang Zhou

As the field of deep learning steadily transitions from the realm of academic research to practical application, the significance of self-supervised pretraining methods has become increasingly prominent. These methods, particularly in the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Toni Albert , Bjoern Eskofier , Dario Zanca

Large-scale models pre-trained on large-scale datasets have profoundly advanced the development of deep learning. However, the state-of-the-art models for medical image segmentation are still small-scale, with their parameters only in the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Ziyan Huang , Haoyu Wang , Zhongying Deng , Jin Ye , Yanzhou Su , Hui Sun , Junjun He , Yun Gu , Lixu Gu , Shaoting Zhang , Yu Qiao