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Protein-nucleic acid interactions play a very important role in a variety of biological activities. Accurate identification of nucleic acid-binding residues is a critical step in understanding the interaction mechanisms. Although many…

Quantitative Methods · Quantitative Biology 2024-01-23 Wenwu Zeng , Dafeng Lv , Wenjuan Liu , Shaoliang Peng

Grounded Multimodal Named Entity Recognition (GMNER) extends traditional NER by jointly detecting textual mentions and grounding them to visual regions. While existing supervised methods achieve strong performance, they rely on costly…

Information Retrieval · Computer Science 2025-11-13 Jielong Tang , Shuang Wang , Zhenxing Wang , Jianxing Yu , Jian Yin

Accurately annotating and controlling protein function from sequence data remains a major challenge, particularly within homologous families where annotated sequences are scarce and structural variation is minimal. We present a two-stage…

Quantitative Methods · Quantitative Biology 2025-07-22 Lorenzo Rosset , Martin Weigt , Francesco Zamponi

In continual time series analysis using neural networks, catastrophic forgetting (CF) of previously learned models when training on new data domains has always been a significant challenge. This problem is especially challenging in vehicle…

Machine Learning · Computer Science 2025-04-08 Arvin Hosseinzadeh , Ladan Khoshnevisan , Mohammad Pirani , Shojaeddin Chenouri , Amir Khajepour

Many edge devices employ Recurrent Neural Networks (RNN) to enhance their product intelligence. However, the increasing computation complexity poses challenges for performance, energy efficiency and product development time. In this paper,…

Neural and Evolutionary Computing · Computer Science 2020-10-27 Chao-Yang Kao , Huang-Chih Kuo , Jian-Wen Chen , Chiung-Liang Lin , Pin-Han Chen , Youn-Long Lin

The discovery of important biomarkers is a significant step towards understanding the molecular mechanisms of carcinogenesis; enabling accurate diagnosis for, and prognosis of, a certain cancer type. Before recommending any diagnosis,…

Quantitative Methods · Quantitative Biology 2019-09-11 Md. Rezaul Karim , Michael Cochez , Oya Beyan , Stefan Decker , Christoph Lange

Transformer-based encoder-decoder models have demonstrated impressive results in chemical reaction prediction tasks. However, these models typically rely on pretraining using tens of millions of unlabelled molecules, which can be…

Computation and Language · Computer Science 2024-05-20 Jiayun Pang , Ivan Vulić

Fine-grained action recognition is a challenging task in computer vision. As fine-grained datasets have small inter-class variations in spatial and temporal space, fine-grained action recognition model requires good temporal reasoning and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-04 Mei Chee Leong , Haosong Zhang , Hui Li Tan , Liyuan Li , Joo Hwee Lim

Recently, attention-based encoder-decoder (AED) models have shown high performance for end-to-end automatic speech recognition (ASR) across several tasks. Addressing overconfidence in such models, in this paper we introduce the concept of…

Audio and Speech Processing · Electrical Eng. & Systems 2021-12-16 Timo Lohrenz , Patrick Schwarz , Zhengyang Li , Tim Fingscheidt

Irregular sampling of time series in electronic health records (EHRs) is one of the main challenges for developing machine learning models. Additionally, the pattern of missing data in certain clinical variables is not at random but depends…

Machine Learning · Computer Science 2024-06-17 Hojjat Karami , David Atienza , Anisoara Ionescu

Chemical reaction prediction is pivotal for accelerating drug discovery and synthesis planning. Despite advances in data-driven models, current approaches are hindered by an overemphasis on parameter and dataset scaling. Some methods…

Machine Learning · Computer Science 2026-03-04 Ran Li , Shimin Di , Haowei LI , Luanshi Bu , Jiachuan Wang , Wangze Ni , Lei Chen

As an important and challenging problem in vision-language tasks, referring expression comprehension (REC) generally requires a large amount of multi-grained information of visual and linguistic modalities to realize accurate reasoning. In…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Peihan Miao , Wei Su , Gaoang Wang , Xuewei Li , Xi Li

Emotion recognition in conversation (ERC) aims to detect the emotion for each utterance in a given conversation. The newly proposed ERC models have leveraged pre-trained language models (PLMs) with the paradigm of pre-training and…

Computation and Language · Computer Science 2022-07-28 Jingjie Yi , Deqing Yang , Siyu Yuan , Caiyan Cao , Zhiyao Zhang , Yanghua Xiao

Developing robust and versatile deep-learning models is essential for enhancing diagnostic accuracy and guiding clinical interventions in medical imaging, but it requires a large amount of annotated data. The advancement of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Nahid Ul Islam , DongAo Ma , Jiaxuan Pang , Shivasakthi Senthil Velan , Michael Gotway , Jianming Liang

Generative recommendation systems have gained increasing attention as an innovative approach that directly generates item identifiers for recommendation tasks. Despite their potential, a major challenge is the effective construction of item…

Information Retrieval · Computer Science 2025-06-05 Enze Liu , Bowen Zheng , Cheng Ling , Lantao Hu , Han Li , Wayne Xin Zhao

This study demonstrates the effectiveness of XLNet, a transformer-based language model, for annotating argumentative elements in persuasive essays. XLNet's architecture incorporates a recurrent mechanism that allows it to model long-term…

Computation and Language · Computer Science 2023-11-13 Christopher Ormerod , Amy Burkhardt , Mackenzie Young , Sue Lottridge

Recurrent Neural Networks (RNNs) have had considerable success in classifying and predicting sequences. We demonstrate that RNNs can be effectively used in order to encode sequences and provide effective representations. The methodology we…

Computer Vision and Pattern Recognition · Computer Science 2015-12-15 Guy Lev , Gil Sadeh , Benjamin Klein , Lior Wolf

Accurate prediction of enzymatic activity from amino acid sequences could drastically accelerate enzyme engineering for applications such as bioremediation and therapeutics development. In recent years, Protein Language Model (PLM)…

Quantitative Methods · Quantitative Biology 2025-05-07 Duncan F. Muir , Parker Grosjean , Margaux M. Pinney , Michael J. Keiser

Regular expression is important for many natural language processing tasks especially when used to deal with unstructured and semi-structured data. This work focuses on automatically generating regular expressions and proposes a novel…

Neural and Evolutionary Computing · Computer Science 2020-06-25 Desheng Wang , Jiawei Liu , Xiang Qi , Baolin Sun , Peng Zhang

A coarse-grained computational procedure based on the Finite Element Method is proposed to calculate the normal modes and mechanical response of proteins and their supramolecular assemblies. Motivated by the elastic network model, proteins…

Biomolecules · Quantitative Biology 2007-05-23 Mark Bathe
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