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Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error, making multi-objective optimization both time-consuming…

Biomolecules · Quantitative Biology 2025-03-06 Jiajun Yu , Yizhen Zheng , Huan Yee Koh , Shirui Pan , Tianyue Wang , Haishuai Wang

Human-AI planning for complex goals remains challenging with current large language models (LLMs), which rely on linear chat histories and simplistic memory mechanisms. Despite advances in long-context prompting, users still manually manage…

Human-Computer Interaction · Computer Science 2025-05-26 Xuanming Zhang , Sitong Wang , Jenny Ma , Alyssa Hwang , Zhou Yu , Lydia B. Chilton

Enhancing fuel efficiency in public transportation requires the integration of complex multimodal data into interpretable, decision-relevant insights. However, traditional analytics and visualization methods often yield fragmented outputs…

Artificial Intelligence · Computer Science 2025-11-18 Zhipeng Ma , Ali Rida Bahja , Andreas Burgdorf , André Pomp , Tobias Meisen , Bo Nørregaard Jørgensen , Zheng Grace Ma

This paper introduces a methodology based on agentic workflows for economic research that leverages Large Language Models (LLMs) and multimodal AI to enhance research efficiency and reproducibility. Our approach features autonomous and…

General Economics · Economics 2025-04-15 Herbert Dawid , Philipp Harting , Hankui Wang , Zhongli Wang , Jiachen Yi

Large Action Models (LAMs) for AI Agents offer incredible potential but face challenges due to the need for high-quality training data, especially for multi-steps tasks that involve planning, executing tool calls, and responding to…

Traditional in-person psychological counseling remains primarily niche, often chosen by individuals with psychological issues, while online automated counseling offers a potential solution for those hesitant to seek help due to feelings of…

Solving different types of optimization models (including parameters fitting) for support vector machines on large-scale training data is often an expensive computational task. This paper proposes a multilevel algorithmic framework that…

Machine Learning · Statistics 2014-10-14 Talayeh Razzaghi , Ilya Safro

We present Adaptive Minds, an agentic system that treats LoRA adapters as domain-specific tools. Instead of relying on a single fine-tuned model or rigid rule-based routing, our approach empowers the base LLM itself to act as a semantic…

Artificial Intelligence · Computer Science 2025-10-20 Pavan C Shekar , Ashwanth Krishnan

To accelerate mechanical design and enhance design quality and innovation, we present a Multidisciplinary Design and Optimization (MDO) Agent driven by Large Language Models (LLMs). The agent semi-automates the end-to-end workflow by…

Human-Computer Interaction · Computer Science 2025-11-25 Bingkun Guo , Wentian Li , Xiaojian Liu , Jiaqi Luo , Zibin Yu , Dalong Dong , Shuyou Zhang , Yiming Zhang

Procedural activity assistants potentially support humans in a variety of settings, from our daily lives, e.g., cooking or assembling flat-pack furniture, to professional situations, e.g., manufacturing or biological experiments. Despite…

Computation and Language · Computer Science 2025-10-02 Kimihiro Hasegawa , Wiradee Imrattanatrai , Masaki Asada , Ken Fukuda , Teruko Mitamura

As Large Language Models increasingly automate complex, long-horizon tasks such as \emph{vibe coding}, a supervision gap has emerged. While models excel at execution, users often struggle to guide them effectively due to insufficient domain…

Artificial Intelligence · Computer Science 2026-02-09 Enyu Zhou , Zhiheng Xi , Long Ma , Zhihao Zhang , Shihan Dou , Zhikai Lei , Guoteng Wang , Rui Zheng , Hang Yan , Tao Gui , Qi Zhang , Xuanjing Huang

Task-oriented communications are an important element in future intelligent IoT systems. Existing IoT systems, however, are limited in their capacity to handle complex tasks, particularly in their interactions with humans to accomplish…

Information Theory · Computer Science 2024-08-12 Hongwei Cui , Yuyang Du , Qun Yang , Yulin Shao , Soung Chang Liew

Software development is a complex, multi-phase process traditionally requiring collaboration among individuals with diverse expertise. We propose AgentMesh, a Python-based framework that uses multiple cooperating LLM-powered agents to…

Software Engineering · Computer Science 2025-07-29 Sourena Khanzadeh

Recent multimodal systems often rely on separate expert modality encoders which cause linearly scaling complexity and computational overhead with added modalities. While unified Omni-models address this via Mixture-of-Expert (MoE)…

Multimedia · Computer Science 2026-03-09 Kin Wai Lau , Yasar Abbas Ur Rehman , Lai-Man Po , Pedro Porto Buarque de Gusmão

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address…

Artificial Intelligence · Computer Science 2025-07-16 Junde Wu , Jiayuan Zhu , Yuyuan Liu , Min Xu , Yueming Jin

Large language models (LLMs) are rapidly evolving from passive engines of text generation into agentic entities that can plan, remember, invoke external tools, and co-operate with one another. This perspective paper investigates how such…

Information Retrieval · Computer Science 2025-07-11 Reza Yousefi Maragheh , Yashar Deldjoo

Generative AI (GenAI) has transformed applications in natural language processing and content creation, yet centralized inference remains hindered by high latency, limited customizability, and privacy concerns. Deploying large models (LMs)…

Systems and Control · Electrical Eng. & Systems 2026-02-10 Haiyuan Li , Hari Madhukumar , Shuangyi Yan , Yulei Wu , Dimitra Simeonidou

Large Language Models (LLMs) in agentic workflows combine multi-step reasoning, heterogeneous tool use, and collaboration across multiple specialized agents. Existing LLM serving engines optimize individual calls in isolation, while…

Databases · Computer Science 2026-01-21 Junyi Shen , Noppanat Wadlom , Yao Lu

Human-AI collaboration faces growing challenges as AI systems increasingly outperform humans on complex tasks, while humans remain responsible for orchestration, validation, and decision oversight. To address this imbalance, we introduce…

Human-Computer Interaction · Computer Science 2026-02-16 Yuanrong Tang , Huiling Peng , Bingxi Zhao , Hengyang Ding , Hanchao Song , Tianhong Wang , Chen Zhong , Jiangtao Gong

Artificial intelligence requires deliberate reasoning, temporal awareness, and effective constraint management, capabilities traditional LLMs often lack due to their reliance on pattern matching, limited self-verification, and inconsistent…

Artificial Intelligence · Computer Science 2025-01-30 Edward Y. Chang
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