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Human-vehicle interaction in safety-critical traffic environments increasingly incorporates neural sensing to infer user intent and cognitive state, yet most existing approaches either treat electroencephalography (EEG) as a static…

Neural and Evolutionary Computing · Computer Science 2026-03-10 Xiaoshan Zhou , Carol C. Menassa , Vineet R. Kamat

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

Progress in neuroscience has provided unprecedented opportunities to advance our understanding of brain alterations and their correspondence to phenotypic profiles. With data collected from various imaging techniques, studies have…

Methodology · Statistics 2024-08-01 Zhe Sun , Wanwan Xu , Tianxi Li , Jian Kang , Gregorio Alanis-Lobato , Yize Zhao

Identification and manipulation of different GABAergic interneuron classes in the behaving animal are important to understand their role in circuit dynamics and behavior. The combination of optogenetics and large-scale neuronal recordings…

Neurons and Cognition · Quantitative Biology 2023-11-20 Lisa Roux , Eran Stark , Lucas Sjulson , György Buzsáki

Electrophysiological observation plays a major role in epilepsy evaluation. However, human interpretation of brain signals is subjective and prone to misdiagnosis. Automating this process, especially seizure detection relying on scalp-based…

Machine Learning · Computer Science 2018-07-06 David Ahmedt-Aristizabal , Clinton Fookes , Kien Nguyen , Sridha Sridharan

Automated seizure detection and classification from electroencephalography (EEG) can greatly improve seizure diagnosis and treatment. However, several modeling challenges remain unaddressed in prior automated seizure detection and…

Signal Processing · Electrical Eng. & Systems 2022-03-15 Siyi Tang , Jared A. Dunnmon , Khaled Saab , Xuan Zhang , Qianying Huang , Florian Dubost , Daniel L. Rubin , Christopher Lee-Messer

Biological signals, such as electroencephalograms (EEG), play a crucial role in numerous clinical applications, exhibiting diverse data formats and quality profiles. Current deep learning models for biosignals are typically specialized for…

Signal Processing · Electrical Eng. & Systems 2023-05-18 Chaoqi Yang , M. Brandon Westover , Jimeng Sun

Brain connectivity analysis based on magnetic resonance imaging is crucial for understanding neurological mechanisms. However, edge-based connectivity inference faces significant challenges, particularly the curse of dimensionality when…

Methodology · Statistics 2025-12-23 Zijing Li , Chenhao Zeng , Shufei Ge

Investigation of human brain states through electroencephalograph (EEG) signals is a crucial step in human-machine communications. However, classifying and analyzing EEG signals are challenging due to their noisy, nonlinear and…

Machine Learning · Statistics 2019-12-19 Farzana Nasrin , Christopher Oballe , David L. Boothe , Vasileios Maroulas

Human emotions are difficult to convey through words and are often abstracted in the process; however, electroencephalogram (EEG) signals can offer a more direct lens into emotional brain activity. Recent studies show that deep learning…

Neurons and Cognition · Quantitative Biology 2025-11-19 Nilay Kumar , Priyansh Bhandari , G. Maragatham

Cognitive load, the amount of mental effort required for task completion, plays an important role in performance and decision-making outcomes, making its classification and analysis essential in various sensitive domains. In this paper, we…

Machine Learning · Computer Science 2023-08-02 Dustin Pulver , Prithila Angkan , Paul Hungler , Ali Etemad

Motivation. Cancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches to link organ- and tissue-level information from diagnostic images and…

Quantitative Methods · Quantitative Biology 2020-05-19 Nova F. Smedley , Suzie El-Saden , William Hsu

Analyzing and reconstructing visual stimuli from brain signals effectively advances the understanding of human visual system. However, the EEG signals are complex and contain significant noise. This leads to substantial limitations in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Honghao Fu , Zhiqi Shen , Jing Jih Chin , Hao Wang

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

Machine Learning · Computer Science 2019-10-17 Tristan Bepler , Bonnie Berger

Prior highly-tuned image parsing models are usually studied in a certain domain with a specific set of semantic labels and can hardly be adapted into other scenarios (e.g., sharing discrepant label granularity) without extensive…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Liang Lin , Yiming Gao , Ke Gong , Meng Wang , Xiaodan Liang

Transfer learning from supervised ImageNet models has been frequently used in medical image analysis. Yet, no large-scale evaluation has been conducted to benchmark the efficacy of newly-developed pre-training techniques for medical image…

Computer Vision and Pattern Recognition · Computer Science 2021-08-16 Mohammad Reza Hosseinzadeh Taher , Fatemeh Haghighi , Ruibin Feng , Michael B. Gotway , Jianming Liang

Connectomics is an emerging field in neuroscience that aims to reconstruct the 3-dimensional morphology of neurons from electron microscopy (EM) images. Recent studies have successfully demonstrated the use of convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-02-27 Shibani Santurkar , David Budden , Alexander Matveev , Heather Berlin , Hayk Saribekyan , Yaron Meirovitch , Nir Shavit

Transfer learning makes use of data or knowledge in one problem to help solve a different, yet related, problem. It is particularly useful in brain-computer interfaces (BCIs), for coping with variations among different subjects and/or…

Human-Computer Interaction · Computer Science 2020-05-12 Wen Zhang , Dongrui Wu