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While analytics of sleep electroencephalography (EEG) holds certain advantages over other methods in clinical applications, high variability across subjects poses a significant challenge when it comes to deploying machine learning models…

Machine Learning · Computer Science 2023-10-05 Manoj Vishwanath , Steven Cao , Nikil Dutt , Amir M. Rahmani , Miranda M. Lim , Hung Cao

Deep learning has proven to successfully learn variations in tissue and cell morphology. Training of such models typically relies on expensive manual annotations. Here we conjecture that spatially resolved gene expression, e.i., the…

Quantitative Methods · Quantitative Biology 2023-12-11 Axel Andersson , Gabriele Partel , Leslie Solorzano , Carolina Wählby

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

Neurons and Cognition · Quantitative Biology 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

When it comes to the classification of brain signals in real-life applications, the training and the prediction data are often described by different distributions. Furthermore, diverse data sets, e.g., recorded from various subjects or…

Instance segmentation in electron microscopy (EM) volumes is tough due to complex shapes and sparse annotations. Self-supervised learning helps but still struggles with intricate visual patterns in EM. To address this, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Yinda Chen , Wei Huang , Xiaoyu Liu , Shiyu Deng , Qi Chen , Zhiwei Xiong

The pattern of Electroencephalogram (EEG) signal differs significantly across different subjects, and poses challenge for EEG classifiers in terms of 1) effectively adapting a learned classifier onto a new subject, 2) retaining knowledge of…

Machine Learning · Computer Science 2021-03-02 Tiehang Duan , Mihir Chauhan , Mohammad Abuzar Shaikh , Jun Chu , Sargur Srihari

Epilepsy is a chronic neurological condition characterized by recurrent seizures, with global prevalence estimated at 50 million people worldwide. While progress in high-throughput sequencing has allowed for broad-based transcriptomic…

Genomics · Quantitative Biology 2025-10-02 Muhammad Omer Latif , Hayat Ullah , Muhammad Ali Shafique , Zhihua Dong

We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

Does the relationship between learning rules and brain alignment generalize across species? We extend our prior finding that untrained CNNs match backpropagation at human V1 by testing the same five learning rules against macaque…

Machine Learning · Computer Science 2026-05-22 Nils Leutenegger

The introduction of deep learning and transfer learning techniques in fields such as computer vision allowed a leap forward in the accuracy of image classification tasks. Currently there is only limited use of such techniques in…

Machine Learning · Computer Science 2019-07-03 Axel Uran , Coert van Gemeren , Rosanne van Diepen , Ricardo Chavarriaga , José del R. Millán

Human motion taxonomies serve as high-level hierarchical abstractions that classify how humans move and interact with their environment. They have proven useful to analyse grasps, manipulation skills, and whole-body support poses. Despite…

Pathology diagnosis based on EEG signals and decoding brain activity holds immense importance in understanding neurological disorders. With the advancement of artificial intelligence methods and machine learning techniques, the potential…

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

In electromyogram (EMG)-based motion recognition, a subject-specific classifier is typically trained with sufficient labeled data. However, this process demands extensive data collection over extended periods, burdening the subject. To…

Signal Processing · Electrical Eng. & Systems 2025-05-22 Seitaro Yoneda , Akira Furui

Reconstructing the intricate local morphology of neurons and their long-range projecting axons can address many connectivity related questions in neuroscience. The main bottleneck in connectomics pipelines is correcting topological errors,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Anna Grim , Jayaram Chandrashekar , Uygar Sumbul

Self-supervised speech models have demonstrated impressive performance in speech processing, but their effectiveness on non-speech data remains underexplored. We study the transfer learning capabilities of such models on bioacoustic…

Machine Learning · Computer Science 2025-12-10 Jules Cauzinille , Marius Miron , Olivier Pietquin , Masato Hagiwara , Ricard Marxer , Arnaud Rey , Benoit Favre

Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system whose molecular mechanisms remain incompletely understood. In this study, we developed an end-to-end machine learning pipeline to analyze transcriptomic…

Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense…

Neurons and Cognition · Quantitative Biology 2019-11-14 Rohan Gala , Nathan Gouwens , Zizhen Yao , Agata Budzillo , Osnat Penn , Bosiljka Tasic , Gabe Murphy , Hongkui Zeng , Uygar Sümbül

Multi-Electrode Arrays (MEAs) have been widely used to record neuronal activities, which could be used in the diagnosis of gene defects and drug effects. In this paper, we address the problem of classifying in vitro MEA recordings of mouse…

Neurons and Cognition · Quantitative Biology 2019-06-07 Yun Zhao , Elmer Guzman , Morgane Audouard , Zhuowei Cheng , PaulK. Hansma , Kenneth S. Kosik , Linda Petzold

Lengthy subject- or session-specific data acquisition and calibration remain a key barrier to deploying electroencephalography (EEG)-based brain-computer interfaces (BCIs) outside the laboratory. Previous work has shown that cross subject,…

Quantitative Methods · Quantitative Biology 2025-06-18 Ziheng Chen , Po T. Wang , Mina Ibrahim , Shivali Baveja , Rong Mu , An H. Do , Zoran Nenadic
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