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In a world where artificial intelligence and data science become omnipresent, data sharing is increasingly locking horns with data-privacy concerns. Differential privacy has emerged as a rigorous framework for protecting individual privacy…

Cryptography and Security · Computer Science 2022-06-06 March Boedihardjo , Thomas Strohmer , Roman Vershynin

For most diseases, building large databases of labeled genetic data is an expensive and time-demanding task. To address this, we introduce genetic Generative Adversarial Networks (gGAN), a semi-supervised approach based on an innovative GAN…

Machine Learning · Computer Science 2020-07-03 Caio Davi , Ulisses Braga-Neto

Synthetic data generation is a key technique in modern artificial intelligence, addressing data scarcity, privacy constraints, and the need for diverse datasets in training robust models. In this work, we propose a method for generating…

The biomedical field is among the sectors most impacted by the increasing regulation of Artificial Intelligence (AI) and data protection legislation, given the sensitivity of patient information. However, the rise of synthetic data…

Machine Learning · Computer Science 2024-04-26 Eric Macias-Fassio , Aythami Morales , Cristina Pruenza , Julian Fierrez

Synthetic data has recently reached a level of visual fidelity that makes it nearly indistinguishable from real data, offering great promise for privacy-preserving data sharing in medical imaging. However, fully synthetic datasets still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Mischa Dombrowski , Bernhard Kainz

This paper introduces provGen, a generator aimed at producing large synthetic provenance graphs with predictable properties and of arbitrary size. Synthetic provenance graphs serve two main purposes. Firstly, they provide a variety of…

Databases · Computer Science 2014-06-11 Hugo Firth , Paolo Missier

Generative Adversarial Network (GAN) and its variants serve as a perfect representation of the data generation model, providing researchers with a large amount of high-quality generated data. They illustrate a promising direction for…

Machine Learning · Computer Science 2020-04-21 Yi Liu , Jialiang Peng , James J. Q Yu , Yi Wu

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Machine Learning · Computer Science 2018-01-18 Romain Lopez , Jeffrey Regier , Michael Cole , Michael Jordan , Nir Yosef

Generative modeling has been used frequently in synthetic data generation. Fairness and privacy are two big concerns for synthetic data. Although Recent GAN [\cite{goodfellow2014generative}] based methods show good results in preserving…

Machine Learning · Computer Science 2023-07-04 Weijie Xu , Jinjin Zhao , Francis Iannacci , Bo Wang

We propose a new framework of synthesizing data using deep generative models in a differentially private manner. Within our framework, sensitive data are sanitized with rigorous privacy guarantees in a one-shot fashion, such that training…

Machine Learning · Computer Science 2022-03-09 Seng Pei Liew , Tsubasa Takahashi , Michihiko Ueno

We revisit the problem of generating synthetic data under differential privacy. To address the core limitations of marginal-based methods, we propose the Private Adaptive Generative Adversarial Network with Bayes Network Structure…

Machine Learning · Statistics 2025-11-12 Ke Jia , Yuheng Ma , Yang Li , Feifei Wang

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

In the social sciences, small- to medium-scale datasets are common, and linear regression is canonical. In privacy-aware settings, much work has focused on differentially private (DP) linear regression, but mostly on point estimation with…

Machine Learning · Computer Science 2026-03-31 Shurong Lin , Aleksandra Slavković , Deekshith Reddy Bhoomireddy

Kinship face synthesis is a challenging problem due to the scarcity and low quality of the available kinship data. Existing methods often struggle to generate descendants with both high diversity and fidelity while precisely controlling…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Pin-Yen Chiu , Dai-Jie Wu , Po-Hsun Chu , Chia-Hsuan Hsu , Hsiang-Chen Chiu , Chih-Yu Wang , Jun-Cheng Chen

Genetic interaction measures how different genes collectively contribute to a phenotype, and can reveal functional compensation and buffering between pathways under genetic perturbations. Recently, genome-wide screening for genetic…

Molecular Networks · Quantitative Biology 2015-03-17 Gang Fang , Wen Wang , Vanja Paunic , Benjamin Oately , Majda Haznadar , Michael Steinbach , Brian Van Ness , Chad L. Myers , Vipin Kumar

Synthetic tabular data enables sharing and analysis of sensitive records, but its practical deployment requires balancing distributional fidelity, downstream utility, and privacy protection. We study a simple, model agnostic post processing…

Machine Learning · Computer Science 2026-02-09 David Yavo , Richard Khoury , Christophe Pere , Sadoune Ait Kaci Azzou

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Shortage of labeled seismic field data poses a significant challenge for deep-learning related applications in seismology. One approach to mitigate this issue is to use synthetic waveforms as a complement to field data. However, traditional…

Geophysics · Physics 2023-10-03 Guoyi Chen , Junlun Li , Hao Guo

Deep generative models are often trained on sensitive data, such as genetic sequences, health data, or more broadly, any copyrighted, licensed or protected content. This raises critical concerns around privacy-preserving synthetic data, and…

Synthetic network data generators (SynNetGens) are increasingly used to share realistic traffic traces without exposing sensitive raw data. While substantial effort has gone into improving fidelity, privacy is either assumed to be a…

Cryptography and Security · Computer Science 2026-05-11 Minhao Jin , Hongyu Hè , Maria Apostolaki