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We study the problem of synthetic generation of samples of environmental features for autonomous vehicle navigation. These features are described by a spatiotemporally varying scalar field that we refer to as a threat field. The threat…

Machine Learning · Computer Science 2025-03-11 Nachiket U. Bapat , Randy C. Paffenroth , Raghvendra V. Cowlagi

Synthetic data offers a scalable solution for vision-language pre-training, yet current state-of-the-art methods typically rely on scaling up a single generative backbone, which introduces generator-specific spectral biases and limits…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Leonardo Brusini , Cristian Sbrolli , Eugenio Lomurno , Toshihiko Yamasaki , Matteo Matteucci

The difficulty of anonymizing text data hinders the development and deployment of NLP in high-stakes domains that involve private data, such as healthcare and social services. Poorly anonymized sensitive data cannot be easily shared with…

Computation and Language · Computer Science 2024-10-14 Krithika Ramesh , Nupoor Gandhi , Pulkit Madaan , Lisa Bauer , Charith Peris , Anjalie Field

Generative adversarial networks (GANs) have attracted intense interest in the field of generative models. However, few investigations focusing either on the theoretical analysis or on algorithm design for the approximation ability of the…

Machine Learning · Computer Science 2020-07-14 Xuejiao Liu , Yao Xu , Xueshuang Xiang

Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic…

The US Decennial Census provides valuable data for both research and policy purposes. Census data are subject to a variety of disclosure avoidance techniques prior to release in order to preserve respondent confidentiality. While many are…

Computers and Society · Computer Science 2025-10-02 Cynthia Dwork , Kristjan Greenewald , Manish Raghavan

Synthetic data is emerging as a promising solution to the scalability issue of supervised deep learning, especially when real data are difficult to acquire or hard to annotate. Synthetic data generation, however, can itself be prohibitively…

Computer Vision and Pattern Recognition · Computer Science 2021-08-20 Aayush Prakash , Shoubhik Debnath , Jean-Francois Lafleche , Eric Cameracci , Gavriel State , Stan Birchfield , Marc T. Law

Genome Wide Association Studies (GWAS) are used to identify statistically significant genetic variants in case-control studies. GWAS typically use a p-value threshold of 5 x 10-8 to identify highly ranked single nucleotide polymorphisms…

Computational Engineering, Finance, and Science · Computer Science 2018-01-10 Paul Fergus , Casimiro Curbelo Montanez , Basma Abdulaimma , Paulo Lisboa , Carl Chalmers

Multimodal self-supervised representation learning has consistently proven to be a highly effective method in medical image analysis, offering strong task performance and producing biologically informed insights. However, these methods…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Lucas Farndale , Chris Walsh , Robert Insall , Ke Yuan

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Growing privacy concerns and regulations like GDPR and CCPA necessitate pseudonymization techniques that protect identity in image datasets. However, retaining utility is also essential. Traditional methods like masking and blurring degrade…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Kartik Patwari , David Schneider , Xiaoxiao Sun , Chen-Nee Chuah , Lingjuan Lyu , Vivek Sharma

Genome-wide association studies, in which as many as a million single nucleotide polymorphisms (SNP) are measured on several thousand samples, are quickly becoming a common type of study for identifying genetic factors associated with many…

Methodology · Statistics 2010-10-25 Charles Kooperberg , Michael LeBlanc , James Y. Dai , Indika Rajapakse

Score-based generative models (SGMs) have recently emerged as a promising class of generative models. However, a fundamental limitation is that their inference is very slow due to a need for many (e.g., 2000) iterations of sequential…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Hengyuan Ma , Li Zhang , Xiatian Zhu , Jianfeng Feng

Generative modeling of single-cell RNA-seq data is crucial for tasks like trajectory inference, batch effect removal, and simulation of realistic cellular data. However, recent deep generative models simulating synthetic single cells from…

Quantitative Methods · Quantitative Biology 2025-03-04 Alessandro Palma , Till Richter , Hanyi Zhang , Manuel Lubetzki , Alexander Tong , Andrea Dittadi , Fabian Theis

Polygenic risk scores (PRS) developed from genome-wide association studies (GWAS) can be used for risk stratification by quantifying the genetic contribution to disease, and many clinical applications have been proposed. Bayesian methods…

Methodology · Statistics 2026-03-11 Yuzheng Dun , Nilanjan Chatterjee , Jin Jin , Akihiko Nishimura

We propose RareGraph-Synth, a knowledge-guided, continuous-time diffusion framework that generates realistic yet privacy-preserving synthetic electronic-health-record (EHR) trajectories for ultra-rare diseases. RareGraph-Synth unifies five…

Machine Learning · Computer Science 2025-10-09 Khartik Uppalapati , Shakeel Abdulkareem , Bora Yimenicioglu

Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within…

Methodology · Statistics 2013-02-26 M. Silver , P. Chen , L. Ruoying , C. Y. Cheng , T. Y. Wong , E. Tai , Y. Y. Teo , G. Montana

The objective of privacy-preserving synthetic graph publishing is to safeguard individuals' privacy while retaining the utility of original data. Most existing methods focus on graph neural networks under differential privacy (DP), and yet…

Databases · Computer Science 2025-01-07 Sen Zhang , Haibo Hu , Qingqing Ye , Jianliang Xu

The widespread adoption of wearable sensors has the potential to provide massive and heterogeneous time series data, driving the use of Artificial Intelligence in human sensing applications. However, data collection remains limited due to…

Machine Learning · Computer Science 2025-12-04 Flavio Di Martino , Franca Delmastro

Children with rare genetic diseases often exhibit distinctive facial phenotypes, yet developing computer vision systems for early diagnosis remains challenging due to extreme data scarcity, privacy constraints, and limited data sharing in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Ganlin Feng , Yuxi Long , Erin Lou , Lianghong Chen , Zihao Jing , Pingzhao Hu , Wei Xu
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