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As dermatological conditions become increasingly common and the availability of dermatologists remains limited, there is a growing need for intelligent tools to support both patients and clinicians in the timely and accurate diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Ali Anaissi , Ali Braytee , Weidong Huang , Junaid Akram , Alaa Farhat , Jie Hua

Clinical decision-making agents can benefit from reusing prior decision experience. However, many memory-augmented methods store experiences as independent records without explicit relational structure, which may introduce noisy retrieval,…

Artificial Intelligence · Computer Science 2026-03-24 Xiao Han , Yuzheng Fan , Sendong Zhao , Haochun Wang , Bing Qin

Accurate and interpretable image-based diagnosis remains a fundamental challenge in medical AI, particularly under domain shifts and rare-class conditions. Deep learning models often struggle with real-world distribution changes, exhibit…

Machine Learning · Computer Science 2025-12-13 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

As Large Multimodal Models (LMMs) scale up and reinforcement learning (RL) methods mature, LMMs have made notable progress in complex reasoning and decision making. Yet training still relies on static data and fixed recipes, making it…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Hongrui Jia , Chaoya Jiang , Yongrui Heng , Shikun Zhang , Wei Ye

Although deep learning-based computer-aided diagnosis systems have recently achieved expert-level performance, developing a robust deep learning model requires large, high-quality data with manual annotation, which is expensive to obtain.…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Sangjoon Park , Gwanghyun Kim , Yujin Oh , Joon Beom Seo , Sang Min Lee , Jin Hwan Kim , Sungjun Moon , Jae-Kwang Lim , Chang Min Park , Jong Chul Ye

Developing AI models that are useful in clinical practice, requires efficient collaboration between clinicians and AI developers. This poses a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Zihao Zhao , Frederik Hauke , Juliana De Castilhos , Mathis Bode , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

Data Darwinism (Part I) established a ten-level hierarchy for data processing, showing that stronger processing can unlock greater data value. However, that work relied on manually designed strategies for a single category. Modern…

Artificial Intelligence · Computer Science 2026-03-17 Tiantian Mi , Dongming Shan , Zhen Huang , Yiwei Qin , Muhang Xie , Yuxuan Qiao , Yixiu Liu , Chenyang Zhou , Pengfei Liu

In contemporary biomedical research, the efficiency of data-driven approaches is hindered by large data volumes, tool selection complexity, and human resource limitations, necessitating the development of fully autonomous research systems…

Quantitative Methods · Quantitative Biology 2024-08-13 Luojia Deng , Yijie Wu , Yongyong Ren , Hui Lu

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Xiang Li , Aoxiao Zhong , Ming Lin , Ning Guo , Mu Sun , Arkadiusz Sitek , Jieping Ye , James Thrall , Quanzheng Li

Clinical decision support systems (CDSS) are widely used to assist with medical decision making. However, CDSS typically require manually curated rules and other data which are difficult to maintain and keep up-to-date. Recent systems…

Human-Computer Interaction · Computer Science 2020-11-20 Zhuochen Jin , Jingshun Yang , Shuyuan Cui , David Gotz , Jimeng Sun , Nan Cao

The increasing inclusion of Deep Learning (DL) models in safety-critical systems such as autonomous vehicles have led to the development of multiple model-based DL testing techniques. One common denominator of these testing techniques is…

Machine Learning · Computer Science 2019-09-09 Houssem Ben Braiek , Foutse khomh

In this work, we introduce MedAgentSim, an open-source simulated clinical environment with doctor, patient, and measurement agents designed to evaluate and enhance LLM performance in dynamic diagnostic settings. Unlike prior approaches, our…

Computation and Language · Computer Science 2025-10-02 Mohammad Almansoori , Komal Kumar , Hisham Cholakkal

Full-process clinical diagnosis in the real world encompasses the entire diagnostic workflow that begins with only an ambiguous chief complaint. While artificial intelligence (AI), particularly large language models (LLMs), is transforming…

Artificial Intelligence · Computer Science 2025-08-15 Shicheng Xu , Xin Huang , Zihao Wei , Liang Pang , Huawei Shen , Xueqi Cheng

Accurate medical diagnosis often involves progressive visual focusing and iterative reasoning, characteristics commonly observed in clinical workflows. While recent vision-language models demonstrate promising chain-of-thought (CoT)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Chunzheng Zhu , Yangfang Lin , Shen Chen , Yijun Wang , Jianxin Lin

Differential diagnosis is an iterative process that integrates patient information with broader medical knowledge. Clinical case series such as the NEJM Clinicopathologic Conferences (CPCs), published continuously since 1923, feature expert…

This research presents an innovative approach to cancer diagnosis and prediction using explainable Artificial Intelligence (XAI) and deep learning techniques. With cancer causing nearly 10 million deaths globally in 2020, early and accurate…

Artificial Intelligence · Computer Science 2024-12-24 Badaru I. Olumuyiwa , The Anh Han , Zia U. Shamszaman

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis…

Artificial Intelligence · Computer Science 2025-03-24 Sihan Wang , Suiyang Jiang , Yibo Gao , Boming Wang , Shangqi Gao , Xiahai Zhuang

While deep learning models have demonstrated remarkable success in numerous domains, their black-box nature remains a significant limitation, especially in critical fields such as medical image analysis and inference. Existing…

Machine Learning · Computer Science 2025-05-13 David Zucker

Self-evolving memory systems are unprecedentedly reshaping the evolutionary paradigm of large language model (LLM)-based agents. Prior work has predominantly relied on manually engineered memory architectures to store trajectories, distill…

Computation and Language · Computer Science 2025-12-23 Guibin Zhang , Haotian Ren , Chong Zhan , Zhenhong Zhou , Junhao Wang , He Zhu , Wangchunshu Zhou , Shuicheng Yan