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Prevailing medical AI operates on an unrealistic ''one-shot'' model, diagnosing from a complete patient file. However, real-world diagnosis is an iterative inquiry where Clinicians sequentially ask questions and order tests to strategically…

Artificial Intelligence · Computer Science 2026-02-02 Yufei He , Juncheng Liu , Zhiyuan Hu , Yulin Chen , Yue Liu , Yuan Sui , Yibo Li , Nuo Chen , Jun Hu , Bryan Hooi , Xinxing Xu , Jiang Bian

Causal inference is central to scientific discovery, yet choosing appropriate methods remains challenging because of the complexity of both statistical methodology and real-world data. Inspired by the success of artificial intelligence in…

Artificial Intelligence · Computer Science 2026-04-07 Can Wang , Hongyu Zhao , Yiqun Chen

Large language models hold promise as scientific assistants, yet existing agents either rely solely on algorithm evolution or on deep research in isolation, both of which face critical limitations. Pure algorithm evolution, as in…

Artificial Intelligence · Computer Science 2025-10-08 Gang Liu , Yihan Zhu , Jie Chen , Meng Jiang

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

The efficacy of AI agents in healthcare research is hindered by their reliance on static, predefined strategies. This creates a critical limitation: agents can become better tool-users but cannot learn to become better strategic planners, a…

Artificial Intelligence · Computer Science 2025-08-08 Huiya Zhao , Yinghao Zhu , Zixiang Wang , Yasha Wang , Junyi Gao , Liantao Ma

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

External knowledge has played a crucial role in the recent development of computer use agents. We identify a critical knowledge-execution gap: retrieved knowledge often fails to translate into effective real-world task execution. Our…

Human-Computer Interaction · Computer Science 2025-11-04 Ziyun Zhang , Xinyi Liu , Xiaoyi Zhang , Jun Wang , Gang Chen , Yan Lu

The rapid proliferation of scientific knowledge presents a grand challenge: transforming this vast repository of information into an active engine for discovery, especially in high-stakes domains like healthcare. Current AI agents, however,…

Artificial Intelligence · Computer Science 2025-10-14 Yinghao Zhu , Yifan Qi , Zixiang Wang , Lei Gu , Dehao Sui , Haoran Hu , Xichen Zhang , Ziyi He , Junjun He , Liantao Ma , Lequan Yu

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Endoscopic diagnosis is an iterative process in which clinicians progressively acquire, compare, and verify local visual evidence before reaching a conclusion. Current AI systems do not adequately support this process because fine-grained…

Artificial Intelligence · Computer Science 2026-05-19 Yi Tang , Kai-Ni Wang , Yang Chen , Xiaopu He , Guangquan Zhou

Automatically extracting useful information from electronic medical records along with conducting disease diagnoses is a promising task for both clinical decision support(CDS) and neural language processing(NLP). Most of the existing…

Computation and Language · Computer Science 2018-04-24 Zhongliang Yang , Yongfeng Huang , Yiran Jiang , Yuxi Sun , Yu-Jin Zhan , Pengcheng Luo

The initial outpatient consultation is critical for clinical decision-making, yet it is often conducted by a single physician under time pressure, making it prone to cognitive biases and incomplete evidence capture. Although the…

Multiagent Systems · Computer Science 2026-04-24 Huangwei Chen , Wu Li , Junhao Jia , Yining Chen , Xiaotao Pang , YaLong Chen , Gonghui Li , Haishuai Wang , Jiajun Bu , Lei Wu

Scientific data processing often requires task-specific algorithms or AI models, creating a barrier for domain scientists who need to analyze their data but may not have extensive computing or image-processing expertise. This barrier is…

Artificial Intelligence · Computer Science 2026-05-26 Ming Du , Xiangyu Yin , Yanqi Luo , Dishant Beniwal , Songyuan Tang , Hemant Sharma , Mathew J. Cherukara

Recent advances in artificial intelligence (AI) agents are pushing AI beyond tools toward autonomous scientific discovery. We discuss two complementary agentic systems for cosmology: \texttt{CMBEvolve}, which targets tasks with explicit…

Instrumentation and Methods for Astrophysics · Physics 2026-05-15 Licong Xu , Thomas Borrett

As the field of artificial intelligence progresses, assistive technologies are becoming more widely used across all industries. The healthcare industry is no different, with numerous studies being done to develop assistive tools for…

Machine Learning · Computer Science 2024-08-29 Abu Adnan Sadi , Mohammad Ashrafuzzaman Khan , Lubaba Binte Saber

High-precision medical diagnosis relies not only on static imaging features but also on the implicit diagnostic memory experts instantly invoke during image interpretation. We pinpoint a fundamental cognitive misalignment in medical VLMs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Chunzheng Zhu , Jiaqi Zeng , Junyu Jiang , Jianxin Lin , Yijun Wang

We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a…

Computation and Language · Computer Science 2026-03-19 Zhongzhen Huang , Yan Ling , Hong Chen , Ye Feng , Li Wu , Linjie Mu , Shaoting Zhang , Xiaofan Zhang , Kun Qian , Xiaomu Li
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