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Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Various imaging modalities are used in patient diagnosis, each offering unique advantages and valuable insights into anatomy and pathology. Computed Tomography (CT) is crucial in diagnostics, providing high-resolution images for precise…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Rabeya Tus Sadia , Jie Zhang , Jin Chen

With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 Yuang Shi , Chen Zu , Mei Hong , Luping Zhou , Lei Wang , Xi Wu , Jiliu Zhou , Daoqiang Zhang , Yan Wang

Lung ultrasound (LUS) is a safe and portable imaging modality, but the scarcity of data limits the development of machine learning methods for image interpretation and disease monitoring. Existing generative augmentation methods, such as…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Maryam Heidari , Nantheera Anantrasirichai , Steven Walker , Rahul Bhatnagar , Alin Achim

Multimodal neuroimaging provides complementary structural and functional insights into both human brain organization and disease-related dynamics. Recent studies demonstrate enhanced diagnostic sensitivity for Alzheimer's disease (AD)…

Multimedia · Computer Science 2025-04-24 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

Positron emission tomography (PET) image denoising, along with lesion and organ segmentation, are critical steps in PET-aided diagnosis. However, existing methods typically treat these tasks independently, overlooking inherent synergies…

MRI synthesis promises to mitigate the challenge of missing MRI modality in clinical practice. Diffusion model has emerged as an effective technique for image synthesis by modelling complex and variable data distributions. However, most…

Image and Video Processing · Electrical Eng. & Systems 2023-03-27 Lan Jiang , Ye Mao , Xi Chen , Xiangfeng Wang , Chao Li

The current clinical diagnosis framework of Alzheimer's disease (AD) involves multiple modalities acquired from multiple diagnosis stages, each with distinct usage and cost. Previous AD diagnosis research has predominantly focused on how to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 Yuxiao Liu , Mianxin Liu , Yuanwang Zhang , Kaicong Sun , Dinggang Shen

Multimodal MR image synthesis aims to generate missing modality images by effectively fusing and mapping from a subset of available MRI modalities. Most existing methods adopt an image-to-image translation paradigm, treating multiple…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Tao Song , Yicheng Wu , Minhao Hu , Xiangde Luo , Linda Wei , Guotai Wang , Yi Guo , Feng Xu , Shaoting Zhang

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline as its main symptom. In the research field of deep learning-assisted diagnosis of AD, traditional convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Yang Ming , Jiang Shi Zhong , Zhou Su Juan

Multi-modal images play a crucial role in comprehensive evaluations in medical image analysis providing complementary information for identifying clinically important biomarkers. However, in clinical practice, acquiring multiple modalities…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Hyunjin Park

Skin lesion classification is essential for early dermatological diagnosis, yet many existing computer-aided systems rely primarily on dermoscopic images and underutilize the multimodal evidence routinely available in clinical practice. To…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Phan Nguyen , Dat Cao , Quang Hien Kha , Hien Chu , Minh H. N. Le , Trang Quoc Thao Pham , Nguyen Quoc Khanh Le

The joint analysis of biomedical data in Alzheimer's Disease (AD) is important for better clinical diagnosis and to understand the relationship between biomarkers. However, jointly accounting for heterogeneous measures poses important…

Methodology · Statistics 2018-08-14 Luigi Antelmi , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Alzheimer's disease (AD) progresses heterogeneously across individuals, motivating subject-specific synthesis of follow-up magnetic resonance imaging (MRI) to support progression assessment. While Diffusion Transformers (DiT), an emerging…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Juneyong Lee , Geonwoo Baek , Ikbeom Jang

Both functional and structural magnetic resonance imaging (fMRI and sMRI) are widely used for the diagnosis of mental disorder. However, combining complementary information from these two modalities is challenging due to their…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Ziyu Zhou , Anton Orlichenko , Gang Qu , Zening Fu , Vince D Calhoun , Zhengming Ding , Yu-Ping Wang

Cross-modal fusion of different types of neuroimaging data has shown great promise for predicting the progression of Alzheimer's Disease(AD). However, most existing methods applied in neuroimaging can not efficiently fuse the functional and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Junren Pan , Shuqiang Wang

Alzheimer's disease (AD) is a prevalent and debilitating neurodegenerative disorder impacting a large aging population. Detecting AD in all its presymptomatic and symptomatic stages is crucial for early intervention and treatment. An active…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Yasmine Mustafa , Tie Luo

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

Machine Learning · Computer Science 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang